2,693 papers found

The tenth Ebola outbreak in the Democratic Republic of Congo (DRC) that occurred from 2018 to 2020 was exacerbated by long-lasting conflicts and war in the region. We propose a deterministic model to investigate the impact of such disruptive events on the transmission dynamics of the Ebola virus disease. It is an exten…

Probiotics can be applied in therapy and mainly in prevention of many civilization disorders. Experimental studies in animal models and clinical trials of patients with inflammatory bowel disease (IBD) have consistently shown that the use of probiotic organisms may effectively down-modulate the severity of intestinal i…

PURPOSE: Gliomas are the commonest malignant brain tumours. Baseline characteristics on structural MRI, such as size, enhancement proportion and eloquent brain involvement inform grading and treatment planning. Currently, free-text imaging reports depend on the individual style and experience of the radiologist. Standa…

Pediatric cancer nursing is a deeply fulfilling yet highly stressful profession as nurses support families during times of intense emotional distress. This study examined the factors influencing job satisfaction among pediatric cancer nurses across Australia and their recommendations to address workplace challenges.A c…

BACKGROUND: Epithelial ovarian cancer kills about 1700 in the UK each year. Ten to fifteen percent of all cases are diagnosed early when there is still a good chance of cure. The treatment of early stage disease involves surgery to remove disease often followed by chemotherapy. The largest clinical trials of this adjuv…

To determine the reliability of knee joint sonography in the evaluation of gouty arthritis.A search of Google Scholar, PubMed, NCBI, MEDLINE, and Medscape databases, from 1988 up to 2020. The key search terms used were knee joint; knee joint ultrasound; gout; gouty arthritis, knee joint pain; sensitivity; specificity.…

Two Caucasian sisters, XZ and YZ, suffered from DH. However, the clinical course of their diseases was different; patient XZ, contrary to her sister YZ, suffered besides dermatitis herpetiformis (DH) also from coeliac disease (CD) and an autoimmune thyroid disease. The sisters were ordered to adhere to gluten-free diet…

We present a method and setup that provide complementary three-dimensional (3D) images of blood oxygenation (via quantitative photoacoustic imaging) and blood flow dynamics (via ultrasound Doppler). The proposed approach is label-free and exploits blood-induced fluctuations, and is implemented on a sparse array with on…

BACKGROUND AND AIM: We analyzed an inclusive gradient boosting model to predict hospital admission from the emergency department (ED) at different time points. We compared its results to multiple models built exclusively at each time point. METHODS: This retrospective multisite study utilized ED data from the Mount Si…

The objective of this focused narrative review is to summarize clinical and preclinical evidence on intracameral bimatoprost implants for adults with open-angle glaucoma (OAG) or ocular hypertension (OHT), focusing on comparative efficacy, safety, and adherence-related outcomes. PubMed/MEDLINE and Google Scholar w…

The front cover artwork is provided by Dr. Karabencheva-Christova's group at Michigan Technological University. The images show the initially formed and the catalytically productive conformations of MMP-1 complex with the Triple Helical Peptide (THP), the free energy profile connecting them as well as the coordination…

Background: Historically, primary care databases have been limited to subsets of the full electronic medical record (EMR) data to maintain privacy. With the progression of artificial intelligence (AI) techniques (i.e., machine learning, natural language processing, and deep learning), practice-based research networks (…

BACKGROUND: Electronic health records (EHR) contain large volumes of unstructured free-form text notes that richly describe a patient's health and medical comorbidities. It is unclear if perioperative risk stratification can be performed directly from these notes without manual data extraction. We conduct a feasibility…

Molecular docking is among the most widely used techniques in structure-based drug discovery and has become integral to natural-product research. Despite substantial advances in computational algorithms and artificial intelligence, the methodological quality of published docking studies on natural compounds remains hig…

Despite the benefits of physical activity and exercise, including high-intensity interval training (HIIT), few cancer survivors meet the exercise oncology guidelines. Emerging evidence suggests peer support (i.e., assistance from individuals with lived experiences trained in behavior change techniques) may improve exer…

The UK has a significant and growing population of older adults with frailty and complex healthcare needs, necessitating innovative care solutions. This study aimed to explore patients' and carers' experiences of a novel integrated service that was set up to address the increasing healthcare needs of older people livin…

Mid-infrared (IR) spectral region is of immense importance for astronomy, medical diagnosis, security and imaging due to the existence of the vibrational modes of many important molecules in this spectral range. Therefore, there is a particular interest in miniaturization and integration of IR optical components. To th…

The conjunctival nevus is one of the most common benign tumors of the ocular surface. Melanomas are rare; they can arise without a preexisting conjunctival nevus, or due to malignant transformation in case of PAM (primary acquired melanosis). The retrospective study analyzed 70 patients with pigmented lesion of the con…

We determine the equilibrium chain end probability density [Formula: see text] for a one-dimensional ideal chain of N monomers grafted to a planar surface. This distribution is also the distribution function of a three-dimensional chain where the tangential dimensions y, z are integrated out of the distribution. With a…

BACKGROUND: Diagnostic testing is overused in emergency departments, and clinical decision support may reduce unnecessary ordering. We examined the effects of nudge-based clinical decision support interventions on test ordering among emergency department clinicians. METHODS: This triple-blind four-arm parallel (1:1:1:…