381,523 papers found

The study of testosterone is likely to be prominent in future epidemiological work on endocrine function and the clinical treatment of age-related diseases. Thus, understanding the hormonal changes involved in the normal male aging process will be critical. Using techniques of meta-analysis, the authors examined 88 pub…

A theoretical basis for similar recurrence rates among H2-receptor antagonists exists based on recent concepts of ulcer recurrence, ulcer healing and suppression of nocturnal gastric acidity. In order to compare H2-receptor antagonists in the maintenance therapy of duodenal ulcer, a meta-analysis was carried out using…

BACKGROUND: Hallux valgus (HV) is a common foot deformity that causes pain and functional limitations. For mild-to-moderate cases, conservative treatment such as exercise therapy and external supports is preferred. Optimal protocols remain uncertain due to variation in exercise types and combinations. This study compar…

Although several dozen studies on individualized instruction in dental education have been conducted over the past 30 years, little has been done to summarize quantitatively these studies. The present investigation used Glass' techniques of meta-analysis to integrate statistically findings from 34 comparative studies o…

PURPOSE: For pediatric primary vesicoureteral reflux (VUR), there are several treatments but a ranking based on comparative efficacy and safety remains unclear. This network meta-analysis aims to rank the effectiveness and safety of multiple treatments for pediatric primary vesicoureteral reflux (VUR). The treatments e…

In primary studies, psychotherapy researchers frequently search for mediator and moderator variables that can help them understand the relationship between treatment and outcome. Yet a review of past psychotherapy meta-analyses revealed that none examined the possible role of mediator variables; and although all of the…

During the 1980's social cognitive theory has evolved as an explanation of human behavior. One of this theory's component constructs, self-efficacy, has received increasing attention as an antecedent to health related outcomes. The results of a meta-analysis examining studies which employed the construct of self-effica…

BACKGROUND AND OBJECTIVE: Benign prostatic hyperplasia (BPH) represents a common condition in aging males. For prostates exceeding 80 g, robotic-assisted simple prostatectomy (RASP) and transurethral prostate enucleation have emerged as leading treatments. This study aimed to comprehensively compare outcomes between th…

In the first part the statistical methods of meta-analysis are discussed. Meta-analysis is considered as a statistical tool for quantitatively summarizing the results of clinical trials with comparable aims (treatments) and designs. Meta-analysis can be based on the significance probabilities or effect values. The last…

The objective of this study is to investigate the strength of the epidemiological evidence for a relationship between smoking and cervical cancer by analysis of recent literature. I conducted a meta-analysis of all eligible case-control studies published in English from 1977 to July 1990, with the primary intent of exa…

Recent studies have reported upper gastrointestinal tract bleeding in 5-25% of intensive care unit (ICU) patients with severe stress despite the use of antacids and/or H2-antagonists. To evaluate the efficacy of this regimen, a meta-analysis of all prospective studies on the prevention of stress bleeding, available fro…

Endoscopic hemostatic therapy for upper gastrointestinal bleeding is gaining widespread acceptance despite often conflicting results of randomized controlled trials. To examine the effect of endoscopic therapy in acute nonvariceal upper gastrointestinal hemorrhage, a meta-analysis was performed using a computerized sea…

The efficacy of fish oil in decreasing restenosis following percutaneous transluminal coronary angioplasty (PTCA) remains controversial despite seven published reports of randomized trials involving 951 patients. We performed a meta-analysis to determine whether these trials, viewed in aggregate, demonstrate a signific…

The physics, physiology, and pathology of electrical conductivity of milk are described. Based on a meta analysis, the use of electrical conductivity as a mastitis detection tool is discussed. Most reports were based on subclinical mastitis data. The gold standards of the different reports are discussed. With an overal…

BACKGROUND: This study aimed to synthesize evidence on the relative effectiveness of antimalarial drugs used as chemoprevention of malaria in pregnancy (MIP) using network meta-analysis (NMA). METHODS: Searches for eligible studies were made in multiple electronic databases, including PubMed. Randomized controlled tri…

In this meta-analysis of 34 clinical studies on attachment the hypothesis is tested that maternal problems such as mental illness lead to more deviating attachment classification distributions than child problems such as deafness. A correspondence analysis on 21 North American studies with normal subjects produced a ba…

This meta-analysis evaluates outcomes in patients undergoing bioprosthetic aortic valve replacement (bAVR), comparing different antithrombotic strategies. We conducted a systematic search through May 2024. A standard meta-analysis compared outcomes between patients who received anticoagulation therapy (AC) and those wh…

BACKGROUND: Projections for major health outcomes are crucial for decision-making to enable early interventions. Pooling results from meta-analyses with estimates based on individual participant data can reduce uncertainty and improve generalizability. However, current methods for meta-meta-analyses of nonlinear functi…

Two recent meta-analyses have generated evidence for child and adolescent psychotherapy effects. However, critics note that such meta-analyses often include studies with methodological shortcomings which might invalidate their results. In the present study, we explored whether the results of the most extensive child/ad…

Publication bias can result from the propensity of researchers to document what is unusual. This can distort the inferences drawn in systematic reviews. To measure the distortion, it has been suggested that a second analysis be done; using weights proportional to the size of the population from which the samples are dr…