2,528 papers found

PURPOSE: This study aimed to provide insights into the staffing and workflow requirements for cone beam computed tomography (CBCT)-guided online adaptive radiation therapy (ART) systems to guide institutions in optimizing staffing strategies and to promote broader ART adoption. METHODS AND MATERIALS: We conducted a na…

CONTEXT: Although it is well established that caloric restriction (CR) is the primary driver of weight loss, circadian-driven metabolic benefits have been recognized as possibly enhancing the effects of CR. Time-restricted eating (TRE) has emerged as a promising approach in this context. OBJECTIVE: We conducted a syst…

OBJECTIVE: The proposed review identifies and describes the extent of Tobacco Harm Reduction (THR) strategies in Pakistan. It also examines the awareness and understanding of these strategies among healthcare professionals and tobacco users in Pakistan. INTRODUCTION: Tobacco consumption poses a significant threat to h…

To assess the psychosocial functioning concerning obsessive-compulsive symptoms (OCS) and/or obsessive-compulsive disorder (OCD) comorbidity in people with schizophrenia, schizoaffective disorder, or bipolar disorder diagnosed in a large case register database in Southeast London. Data were retrieved from the South Lon…

INTRODUCTION/OBJECTIVE: Graft stones in renal transplant recipients pose a unique challenge, finding effective interventions to ensure optimal graft function and patient well-being. Various methods of stone clearance have been described for graft stones, including percutaneous nephrolithotomy (PCNL). While PCNL is a pr…

BACKGROUND: We have shown previously that current recommendations in UK guidelines for monitoring long-term conditions are largely based on expert opinion. Due to a lack of robust evidence on optimal monitoring strategies and testing intervals, the guidelines are unclear and incomplete. This uncertainty may underly var…

BACKGROUND: Current field-directed treatments of actinic keratosis (AK), a pre-malignant condition, are often limited by severe local reactions and/or complex treatment. Tirbanibulin, a novel potent anti-proliferative synthetic agent that inhibits tubulin polymerization and Src kinase signalling, is being developed as…

BACKGROUND: Free tissue transfer for lower limb reconstruction has become a workhorse procedure for limb-salvage. Compared with other recipient sites, the lower extremity has a higher risk of microvascular complications, in particular with venous anastomosis. The study's objective is to evaluate the evidence, safety, a…

OBJECTIVE: To systematically evaluate the scientific literature for patient-reported outcome measures (PROMs) in static computer-aided implant surgery (s-CAIS). METHODS: A PICO strategy was executed using an electronic (MEDLINE, EMBASE, CENTRAL), plus manual search up to 15-06-2017 focusing on clinical studies investi…

BACKGROUND: Obesity is a worldwide epidemic in children and adolescents. Adult cohort studies have reported an association between higher body mass index (BMI) and increased leukemia-related mortality; whether a similar effect exists in childhood leukemia remains controversial. OBJECTIVE: We conducted a meta-analysis…

BACKGROUND: Active smoking increases the risk of tuberculosis (TB) infection 2 to 2.5 times and is significantly associated with recurrent TB and TB mortality. Observational studies have shown associations between smoking and poor TB treatment outcomes such as increased loss to follow-up rate, severity of disease, drug…

CONTEXT AND AIM: Asthma is a common problem in paediatric population. International treatment guidelines recognize the role of inhaled corticosteroids for asthma in young children. Inhaled fluticasone propionate is reported to have greater systemic effects like other corticosteroids. Limited data is available on safety…

AIM: Studies on the use of intrathecal baclofen (ITB) for ambulant adults with spasticity and/or dystonia of cerebral origin are scarce, and are even more limited for children and adolescents. This systematic review investigates the use of ITB to improve walking, transfer ability, and gross motor activities in ambulant…

INTRODUCTION: Case reports have been used as an educational tool in medicine for a long time, as they are usually the first kind of publications prepared by new authors. In compliance with the rules of the EBM, the evidence-based medicine, a clinical case report (which describes and analyses the manner of diagnosis and…

Clear documentation and transfer of information between health care providers is key to ensuring the delivery of high-quality patient care. Our aim was to determine how to optimize and standardize physician documentation in outpatient epilepsy clinics as well as to highlight challenges and barriers to their implementat…

Our goal was to understand the barriers and challenges to clinical translation of quantitative MR (qMR) as perceived by stakeholders in the UK. We conducted an electronic survey on seven key areas related to clinical translation of qMR, developed at the BIC-ISMRM workshop: "Steps on the path to clinical translation". B…

OBJECTIVE: This study aims to update the prognostic value of perineural invasion(PNI) in various subgroups of esophageal cancer patients. METHODS: We searched databases including PubMed, Scopus, Wiley, Web of Science, and Embase for full-text articles published in English on esophageal cancer related to PNI. The searc…

BACKGROUND AND OBJECTIVE: Early recognition and treatment of sepsis in the emergency department (ED) is important. Traditional predictive analytics and clinical decision rules lack accuracy in identifying patients with sepsis. Artificial intelligence (AI) is increasingly prevalent in healthcare and offers application p…

BACKGROUND/SIGNIFICANCE: Alcohol use carries significant morbidity and mortality, yet accurate identification of alcohol use disorder (AUD) remains a multi-layered problem for both researchers and clinicians. OBJECTIVE: To fine-tune a language model to AUD in the clinical narrative and to detect AUDs not accounted for…

We aimed to conduct a systematic review and meta-analysis to summarize the current evidence regarding the role of super-mini percutaneous nephrolithotomy (SMP), which refers to a 7-Fr nephroscope placed through a tract sized 10-14 Fr, in treating renal stones and compare its outcomes with the standard mini-percuta…