2,694 papers found

BACKGROUND AND PROBLEM STATEMENT: Neurophobia, the fear of, discomfort with, and dislike of clinical neurology, is frequently due to poor experiences in preclinical neuroscience education among medical providers. We developed, implemented, and assessed a curricular innovation using clinician-educators and team-based le…

OBJECTIVES: We conducted an updated review of the literature on pulmonary-specific ancillary therapies for pediatric acute respiratory distress syndrome (PARDS) to provide an update to the Pediatric Acute Lung Injury Consensus Conference recommendations and statements about clinical practice and research. DATA SOURCES…

OBJECTIVE: To better understand the perspectives of the 2025 urology residency applicant cohort by analyzing survey data on key aspects of the application process. METHODS: A survey consisting of 38 questions designed by the Society of Academic Urologists was distributed by American Urological Association to all appli…

BACKGROUND AND OBJECTIVES: Serious games (SGs) are increasingly used in education, although data on their use in neurology education are limited. This study evaluates SG effect on knowledge retention, subjective impression of decision making, and learner satisfaction. METHODS: Using a 6-step approach to curriculum dev…

OBJECTIVE: To examine how the pandemic affected women with pelvic dysfunction. METHODS: A Survey Monkey™ online questionnaire on how the pandemic and Covid-19 infection affected women's pelvic problems, exercise, and weight. A free text box captured their comments. RESULTS: Six hundred and forty-seven women to…

Ventricular entry during resection of periventricular gliomas may increase the risk of cerebrospinal fluid (CSF)-related complications, while optimal management of ependymal defects remains uncertain. We evaluated the feasibility, short-term safety, and postoperative imaging characteristics of onlay TachoSil® vent…

Artificial intelligence (AI) has rapidly emerged as a promising tool for delivering personalized interventions in physical activity, exercise prescription, and weight management. AI technologies may facilitate individualized recommendations, behavioral support, and lifestyle modification through adaptive digital health…

Dental cracks are a common yet diagnostically challenging condition due to their asymptomatic clinical nature and difficulty in early detection. Accurate diagnosis is essential to prevent crack progression and potential tooth loss; however, no universally accepted diagnostic method exists.To systematically evaluate the…

BACKGROUND: Temozolomide (TMZ) and other alkylating agents (ALK) yield high response rates when used in metastatic neuroendocrine tumors (NETs). Several series reported higher response rates when used in tumors with low expression of O6-Methylguanine DNA Methyltransferase (MGMT) with immunohistochemistry or promoter me…

BACKGROUND AND OBJECTIVE: Early recognition and treatment of sepsis in the emergency department (ED) is important. Traditional predictive analytics and clinical decision rules lack accuracy in identifying patients with sepsis. Artificial intelligence (AI) is increasingly prevalent in healthcare and offers application p…

Retinopathy of prematurity (ROP) is a rare proliferative ocular condition that can happen in premature babies (born preterm&#xa0;<36 weeks)&#xa0;or who weigh <1.5 kg&#xa0;at birth (low birth weight babies). ROP is a major cause of childhood blindness. It is a premature disease&#xa0;since retina vascularization is compl…

OBJECTIVES: Pressure ulcers are the most common condition among palliative care patients at home care facilities and impose a significant burden on patients, their relatives, and caregivers. Caregivers play a vital role in preventing pressure ulcers. When the caregivers are knowledgeable about preventing pressure ulcer…

We aimed to conduct a systematic review and meta-analysis to summarize the current evidence regarding the role of super-mini percutaneous nephrolithotomy (SMP), which&#xa0;refers to a 7-Fr nephroscope placed through a tract sized 10-14 Fr, in treating renal stones and compare its outcomes with the standard mini-percuta…

BACKGROUND AND OBJECTIVES: Patients with kidney failure experience depression at rates higher than the general population. Despite the Centers for Medicare and Medicaid Services' ESRD Quality Incentive Program requirements for routine depression screening for patients with kidney failure, no clear guidance exists. DES…

BACKGROUND: Arterial hypertension (HT) is common in the Russian adult population, with half of affected individuals inadequately controlled. Low adherence to medication seems likely to be a factor. We report a scoping review of studies on adherence to antihypertensive therapy (AHT) in Russia to determine the extent of…

BACKGROUND: Guidelines recommend treating patients with an internal carotid artery near occlusion (ICANO) with best medical therapy (BMT) based on weak evidence. Consequently, patients with ICANO were excluded from randomized trials. The aim of this individual-patient data (IPD) meta-analysis was to determine the optim…

BACKGROUND: In patients with inflammatory bowel disease, we strive to achieve mucosal healing, as this has been shown to decrease the risk of disease flares, hospitalization, and surgery. For this reason, we must use objective measures of mucosal healing to inform our clinical decision-making and can no longer rely on…

OBJECTIVE: Depression affects approximately 25% of epilepsy patients. However, the optimal tool to screen for depression in epilepsy has not been definitively established. The purpose of this study was to systematically review the literature on the validity of depression-screening tools in epilepsy. METHODS: MEDLINE,…

PURPOSE: Given serious concerns over the adverse effects of enzyme induction, modern nonenzyme-inducing antiepileptic drugs (AEDs) may be preferable, provided they have similar efficacy as enzyme-inducing AEDs. This is currently unclear. METHODS: Therefore, we performed a meta-analysis of the evidence to determine the…

Assessment of long-term outcomes is essential in brain surgery for epilepsy. Little information exists on long-term non-seizure outcomes after epilepsy surgery. We perform a systematic review and meta-analysis of the evidence on this topic. Our aim was to provide evidence-based estimates of antiepileptic drug, psychoso…