Multidisciplinary treatment for central nervous system tumours with nitrosourea compounds.
Paoletti P, Robustelli della Cuna G, Knerich R, +1 more·Acta neurochirurgica
The authors report the results of a controlled clinical trial in patients with primitive and metastatic CNS tumours treated with combined therapy: surgery, radiotherapy, and chemotherapy (BCNU or CCNU). A total of 102 patients were treated, 50 with BCNU, and 52 with CCNU. The overall response (R. + P.R.) was 68% for th…