98,289 papers found

BACKGROUND: Bacterial meningitis (BM) remains a considerable cause of morbidity. OBJECTIVES: To evaluate BM incidence rate trends in diverse age groups. METHODS: We conducted a retrospective cohort study based on the Israeli national registry. Inclusion criteria were acute admissions 2000 to 2019 with primary diagnos…

BACKGROUND: Early adiposity rebound (AR, below 5 years) is an important predictor of adult obesity. OBJECTIVES: The main purpose of this study was to explore changes in body weight and height, BMI, body fat, and AR timing in girls from Krakow within the last 3 decades. METHODS: 1,970 girls were measured in 2010. Usin…

Self-perceived psychological stress as a risk factor for coronary artery disease (CAD) was evaluated in a general population study comprising 6,935 men aged 47 to 55 years at baseline without previous myocardial infarction. In 1970 to 1973, the men answered a question about psychological stress defined as a feeling of…

Tubular renal toxicity is a side-effect of long-term therapy with nucleos(t)ide analogue(s) (NA) in chronic hepatitis B (CHB). There are no established surrogate markers in plasma of early NA-related toxicity. Neutrophil gelatinase-associated lipocalin (NGAL) is a protein produced by tubular cells following renal damag…

Histone post-translational modifications (PTMs) have been linked to a variety of biological processes and disease states, thus making their characterization a critical field of study. In the last 5 years, a number of novel sites and types of modifications have been discovered, greatly expanding the histone code. Mass s…

OBJECTIVE: To explore whether patients' pain experiences and orthodontists' assessments of their patients' pain levels are consistent and whether orthodontists are aware of their patients' use of pain medication. MATERIALS AND METHODS: Survey data were collected from 116 adolescent patients (44 male, 72 female; aged 1…

INTRODUCTION: This is a review of the epidemiology and trends of sexually transmitted infections (STIs) in Singapore from 1994 to 2003. MATERIALS AND METHODS: Data collated for both notifiable and non-notifiable STIs from 1994 to 2003 were analysed. This data consisted of STI notifications from medical practitioners i…

OBJECTIVES: Each case of a continuous series of invasive cervical cancer cases was studied with a structured review procedure conducted by an expert panel to assess the reason that it was not detected before it became invasive. METHODS: All cases of invasive cervical cancer diagnosed in a 5-year period among Connectic…

OBJECTIVE: Introduction: During last year's, Ukraine and other European countries are facing outbreaks of well-known and emergency infections. Particularly alarming is the increase in the incidence of measles, which may be the result of a sharp decline of immunization that leads to the accumulation of susceptible indiv…

OBJECTIVE: To evaluate the vaccination coverage rate of patients with JIA followed at a paediatric tertiary care centre and to determine the coverage rate for individual vaccines required as per the Quebec Immunization Protocol. METHODS: Consecutive JIA patients coming for their scheduled visit were included if they w…

In this paper, we calculate a base line of statistical data on the frequency of sexual activity at various ages of Taiwanese women. A cross-sectional study using questionnaires administered during personal interviews was conducted on more than seventeen thousand women who attended family planning clinics in the Taipei…

BACKGROUND: Manipulation under anesthesia (MUA) as treatment for idiopathic frozen shoulder increases motion, provides pain relief, and restores function, but it is unclear whether the improvements persist long term. QUESTIONS/PURPOSES: We therefore investigated whether (1) ROM was restored, (2) pain was relieved, and…

BACKGROUND: Regular recertification is mandatory to maintain board certification status in all specialties. However, the evidence that physicians' performance decreases with time since initial certification is limited. We therefore carried out a study to determine whether the frequency of antihypertensive treatment int…

OBJECTIVE: Evaluate long-term prevalence of tumor growth and need for further treatment in patients with a vestibular schwannoma treated with conservative management. STUDY DESIGN: Retrospective chart review. SETTING: Private neurotologic tertiary referral center. PATIENTS: Vestibular schwannoma patients undergoing…

Patients older than 40 years with a body-mass-index (BMI) >30 kg/m, a femoroacetabular-impingement (FAI) and little cartilage damage are a challenge for hip surgeons. Hip-arthroscopy (HAS) or conservative therapy until a total hip arthroplasty (THA) is needed are possible treatments. Our research purpose…

OBJECTIVE: To determine the relation between the detection of genital human papillomavirus (HPV) DNA and the number of new sexual partners in the last year, 1-5 years, and 5-10 years. METHODS: In a cross-sectional study, 298 women collected tampon specimens and completed self-answer questionnaires on the known risk fa…

BACKGROUND: Cup arthroplasty was used in the initial attempts to preserve the bone stock of the femoral head and neck for hip reconstruction. However, little conclusive data are available regarding its long-term survivorship. METHODS: We present a long-term survivorship analysis (mean follow-up, 19.3 years; range, 5-3…