381,523 papers found

The cesarean birth rate has continued to climb despite efforts to counteract this trend. A major reason for this rise is the practice of doing an elective repeat cesarean. Our study used a statistical model of meta-analysis to analyze the findings of 29 individual studies that looked at the association between the succ…

OBJECTIVES: To empirically evaluate the performance of methods for estimating odds ratios and their corresponding standard errors from continuous end point data for meta-analysis. STUDY DESIGN AND SETTING: A database of randomized controlled trials of chronic depression treatments was used. Trials that reported both c…

BACKGROUND: Community-based rehabilitation is critical for functional recovery in older adults after hip fracture, yet the optimal strategy remains uncertain. Previous reviews are limited by the pooling of heterogeneous interventions and an incomplete assessment of evidence quality. This network meta-analysis (NMA) aim…

We identified 24 modern studies of childhood exposures to lead in relation to IQ. From this population, 12 that employed multiple regression analysis with IQ as the dependent variable and lead as the main effect and that controlled for nonlead covariates were selected for a quantitative, integrated review or meta-analy…

A meta-analysis was carried out of the data from two double-blind, multi-centre studies with identical methodology which compared the effectiveness of treatment of elderly patients with zuclopenthixol and with other antipsychotic drugs. In one study, patients were treated for 4 weeks with either zuclopenthixol or melpe…

Although penicillin has been the antibiotic of choice for therapy of Group A beta-hemolytic streptococcal pharyngitis for more than four decades, reports of bacteriologic and clinical treatment failures with penicillin have increased in recent years. We conducted a meta-analysis of 19 studies to examine whether oral ce…

Abstract The aim of this meta-analysis was to compare the efficacy and safety profile of manidipine 20 mg with that of amlodipine 10 mg. A systematic research of quantitative data produced or published between 1995 and 2009 was performed. Head-to-head randomized controlled trials (RCTs) of 12 months minimum duration re…

This report presents a meta-analysis of a series of published 16PF findings which describe score profiles of nine groups of substance users/abusers, a nonuser comparison group, seven psychiatric groups, a group of criminals, and a group of gang delinquents. Analytical procedures include K Means Clustering, Cattell's rp…

Reocclusion of infarct-related coronary arteries within 2 weeks of thrombolytic therapy varies from 5% to 45% and neither clinical nor angiographic variables have been proved to be predictive of reocclusion. The goal of the present study was to evaluate whether aspirin could prevent coronary reocclusion and recurrent i…

The results are described of a meta-analysis of seven randomized trials that compared the clinical effects of the standard solution of WHO oral rehydration salts (ORS), containing 20 milligrams of glucose, and experimental ORS solutions, containing glycine, on 643 children with acute noncholera diarrhoea. The availabil…

Interpretation of the prognostic value of cranial ultrasound abnormalities in preterm infants has been hampered by the lack of a uniform approach to research, especially in the definition and classification of the abnormal appearances. Defining normality should be less controversial, but from a selected reading of the…

Using a method of literature review known as meta-analysis, 81 articles were selected describing comparative research into possible differences between two or more of the following groups: nonsuicidals, suicide ideators, first-ever attempters, nonlethal repeaters, and suicides. Differential characteristics are describe…

The relation of marital discord to the behavior problems of children was examined through a meta-analysis of the results of prior research. The sample comprised all published studies through 1988 that met criteria for the meta-analysis and that could be located through a combined computer and hand search of the literat…

Estimates of the risks associated with the use of radiologic contrast agents frequently are based on a subjective review of some of the numerous articles that have been published on the subject. We have chosen instead to synthesize the existing evidence in an objective, quantitative way by statistically combining the d…

OBJECTIVE: Clinical experience and patient-level physiological studies indicate that albuterol transiently reduces oxygen saturation, irrespective of the underlying respiratory condition causing the wheezing. Three revisions of the Cochrane review, Bronchodilators for Bronchiolitis (Review), have found that albuterol t…

Because selection of studies for a literature review influences conclusions, inclusion criteria are of utmost importance. For a meta-analysis of studies testing effects of patient education on preventive behaviors, we present the framework and concepts used for setting inclusion criteria for primary studies. We also pr…