42,344 papers found

BACKGROUND/OBJECTIVES: The detection of dental caries in the early stages, particularly on the occlusal surfaces, has become a mainstay of contemporary clinical practice. The objective of the study was to verify the accuracy of laser fluorescence for caries detection. METHODS: A comprehensive search of the MEDLINE (Pu…

BACKGROUND: The lifelong nature of autism in a child has deep implications on parents as they are faced with a range of challenges and emotional consequences in raising the child. The aim of this meta-synthesis was to explore the perspectives of parents in raising a child with autism in the childhood period to gain an…

INTRODUCTION: Several experimental and clinical studies suggest that drugs used in pediatric anesthesia may exert undesirable effects on the developing central nervous system. The objective of this review was to assess the results and conclusions of published studies on long lasting neurodevelopment disorders following…

Joint arthroplasty registries show an increased rate of aseptic loosening in uncemented acetabular components as compared to cemented acetabular components. Since loosening is associated with particulate wear debris, we postulated that uncemented acetabular components demonstrate a higher polyethylene wear rate than ce…

AIM: To survey the literature on Pediatric Emergency Medical Services (PEMS) with an aim to focus its drawbacks and emphasize the means of improvement. MATERIALS AND METHODS: Published articles selected for inclusion were based on the significance and understanding of literature search on different aspects of PEMS. To…

BACKGROUND: Persons with central neurological disorders frequently experience gait impairments which are often associated with joint hyper-resistance. To assess joint hyper-resistance, clinical assessments generally rely on passive joint rotations, yet their specific relationship with gait impairments remains unclear.…

The major therapeutic challenge in inflammatory rheumatic diseases is the persistence of pain despite good responses to specific therapies. Central sensitization, which can be assessed clinically by psychophysical measurements, including quantitative sensory testing (QST), is a widely proposed mechanism for chronic pai…

PURPOSE: Emerging evidence suggests that choroidal microcirculation and microstructural changes after verteporfin photodynamic therapy (vPDT) for chronic central serous chorioretinopathy (CSC) can be shown in detail using OCT-Angiography (OCT-A). The use of OCT-A for the examination of choriocapillaris (CC) has attract…

BACKGROUND: Calcium-binding proteins are heterogeneous proteins that act binding this ion in specific domains, performing numerous functions. OBJECTIVE: In the present review, we aim to gather principal information about S100B protein in the Central Nervous System (CNS), highlighting its particularities, mapping, func…

The effect of rituximab on primary central nervous system lymphoma (PCNSL) is controversial. We performed this meta-analysis to assess the efficacy of treatment with or without rituximab for PCNSL. We first conducted a search for qualified studies using PubMed, the Cochrane Library, and the Web of Science. The meta-ana…

ETHNOPHARMACOLOGICAL RELEVANCE: Xysmalobium undulatum, commonly known as uzara, is traditionally used as an antidiarrhoeal and to treat stomach cramps, dysmenorrhoea and afterbirth cramps. In addition, it was reportedly used to treat anxiety and other conditions relating to mental health. AIM OF THE REVIEW: To unite t…

OBJECTIVES: To analyze literature on the additional value of fetal magnetic resonance imaging (MRI) in assessing central nervous system (CNS) anomalies suspected by ultrasound. METHODS: A search was performed of PubMed, EMBASE, Cochrane library and the reference lists of identified articles. Inclusion criteria were CN…

The association between central sensitivity syndrome (CSS) and sensory processing sensitivity (SPS) demonstrates the need for assessment tools that quantify the physical and psychological alterations observed in these two conditions in order to generate multidisciplinary treatments and establish their effectiveness. Th…

OBJECTIVES: The present study aims to determine the effects of joint manual therapy (MT) on central sensitization (CS) in individuals with Chronic low back pain (CLBP). METHODS: A systematic search was performed in PubMed, Scopus, ScienceDirect, Embase/Ovid, CINHAL, CENTRAL, Web of Science and PEDRO, clinicaltrials.go…

Venous access devices can be categorized based on the termination site of the tip of the catheter into central and peripheral access devices. Selecting the type of venous access device depends on various factors, including the condition of the patient, the anticipated duration of therapy, the use of vesicant or hyperos…

BACKGROUND: Birth asphyxia leads to about 4 million neonatal deaths every year around the globe. But, the pooled prevalence of asphyxia was not yet collated in East and Central African countries. Hence, this systematic review and meta-analysis aimed to determine the pooled prevalence of perinatal asphyxia in Central an…

INTRODUCTION: The central auditory system and its maturational aspects have been a topic of interest on the raise in recent times. Cortical auditory evoked potentials (CAEP) might be a promising electrophysiological tool, applicable both in the diagnosis of central auditory processing disorders and other conditions, as…

INTRODUCTION: Central nervous system (CNS) infections are a health concern, leading to high morbidity and mortality. Community-acquired and nosocomial meningitis are distinct entities with potentially different pathogens involved. Prompt antibiotic therapy is crucial. However, challenges arise due to the emergence of m…

Central nervous system lymphoma (CNSL) presents diagnostic and prognostic challenges. The aim of this meta-analysis was to evaluate the diagnostic and prognostic value of interleukin (IL)-10 in cerebrospinal fluid (CSF) for CNSL comprehensively. PubMed and Cochrane Library databases were searched through September 2016…

BACKGROUND: Early intervention in psychosis (EIP) is a key component of youth mental health care, yet recommended models of care for individuals at clinical high risk for psychosis (CHR-P) and first-episode psychosis (FEP) remain heterogeneous across jurisdictions. No previous study has combined a formal AGREE II appra…