5,083,489 papers found

Self-poisoning is a common method of suicide, for which various medications are used, including antidepressants. A non-systematic review of Russian-language and English-language publications, by keywords, in the databases: ELibrary.ru, PubMed, Cochrane Database of Systematic Reviews. The purpose of the review was to an…

Population-level compliance with health protective behavioral advice to prevent and control communicable disease is essential to optimal effectiveness. Multiple factors affect perceptions of trustworthiness, and trust in advice providers is a significant predeterminant of compliance. While competency in assessment and…

Here, we report a new case of botryoid Wilms' tumor, a 4-year-old boy, who was referred to us with a chief complaint of dysuria and gross hematuria. The computed tomography and radical nephroureterectomy showed that a botryoid sarcoma-like appearance occupied the right renal pelvis and extended into the bladder. Histol…

Clear cell carcinoma of the bladder is a rare tumor of the bladder. There are few reports available on this rare disease, and no cases with recurrence were reported. Here we present a case of 68-year-old woman with primary clear cell carcinoma of the bladder, who underwent repeat TUR-BT and tumor recurrence. We also re…

While the over-representation of the elderly in the breast cancer population is projected to dramatically increase within the next two decades, data on chemotherapy for elderly patients with metastatic breast carcinoma (MBC) remain very limited. The aim of the present study is to investigate whether elderly patients in…

OBJECTIVE: Cochrane reviews have the reputation for being more transparent and rigorous than other reviews. The aim of this overview was to evaluate and summarize Cochrane reviews of acupuncture for the treatment of any type of pain. METHODS: We searched the Cochrane Database and evaluated the Cochrane reviews that we…

Myeloid colony-stimulating factors (M-CSFs), which include granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF), regulate the proliferation and differentiation of myeloid cells. Their use has an important role in the treatment of hematologic malignancies. Guideline…

As the average age of a renal transplant candidate increases, the challenge of managing recipient vascular disease affecting renal allograft function will become more common. Pre-operative screening can reveal the presence of atheromatous disease that could adversely affect allograft transplantation and function, but p…

INTRODUCTION: The peritoneal cavity is the most common site of cerebrospinal fluid absorption in hydrocephalus treatment. Many distal catheter complications are the result of this type of treatment, and these have been extensively described in the neurosurgical literature. MATERIALS AND METHODS: In our study, six case…

OBJECTIVE: To explore trends in published protocols of systematic reviews (SRs) and to analyze how SRs with published protocols differ from those without. STUDY DESIGN AND SETTING: We searched PubMed up to December 31, 2016 to identify SR protocols. We also searched for the corresponding SR for each protocol published…

BACKGROUND: Despite many systematic reviews and meta-analyses examining the associations of pregnancy complications with risk of type 2 diabetes mellitus (T2DM) and hypertension, previous umbrella reviews have only examined a single pregnancy complication. Here we have synthesised evidence from systematic reviews and m…

OBJECTIVES: The aim of this study was evaluate the effect of Platelet-Rich Fibrin (PRF) in patients after mandibular third molar extraction through an analysis of the most current literature on systematic reviews and meta-analyses. DATA, SOURCES AND STUDY SELECTION: By using computer-assisted search technology, we com…

OBJECTIVE: This study aims to explore the current practice of risk of bias assessment in systematic reviews of behavioral clinical trials published in substance use journals and how assessment results were incorporated into meta-analysis. STUDY DESIGN AND SETTING: The authors searched for systematic reviews and meta-a…

CONTEXT: Some studies suggest that consumption of dairy products can aid in weight loss, while others suggest a negative effect or no effect. OBJECTIVE: An overview of systematic reviews and meta-analyses was conducted to examine the effect of dairy product consumption on changes in body composition. DATA SOURCES: PR…

INTRODUCTION: Super-refractory status epilepticus is defined as status epilepticus that persists or recurs 24 hours after anaesthetic therapy onset or after its withdrawal. It is mostly found in intensive care units and carries high mortality but good long-term prognosis for those who survive. In contrast wit…

STUDY OBJECTIVES: To assess the methodological quality of published systematic reviews (SRs) and meta-analyses (MAs) about the efficacy of oral appliances (OA) in the management of adult and pediatric sleep-disordered breathing (SDB). METHODS: SRs/MAs that evaluated the efficacy of OA therapy on the treatment of SDB i…

BACKGROUND: Sensors and digital devices have revolutionized the measurement, collection, and storage of behavioral and physiological data, leading to the new term digital biomarkers. OBJECTIVE: This study aimed to investigate the scope of clinical evidence covered by systematic reviews (SRs) of randomized controlled t…

OBJECTIVE: This umbrella review aims to comprehensively evaluate the effects of weight loss and various weight loss interventions, like bariatric surgery, dietary modifications, and physical activity, on sex hormone profiles in adults. The goal is to synthesize existing systematic reviews and meta-analyses to clarify t…

Vulvovaginal candidiasis (VVC) is one of the most common infections of the genital tract in women of reproductive age. In this umbrella review, we aim to summarize all the existing literature about different treatment strategies for vulvovaginal candidiasis. This umbrella review adhered to the PRISMA guidelines, system…

A number of research studies have indicated a potential association between COVID-19 and acute kidney injury (AKI). However, the methodologies employed and the risk estimates derived from these studies vary. Therefore, an umbrella review of systematic reviews and meta-analyses was conducted to determine the incidence o…