11,609,670 papers found

INTRODUCTION: It is now clear that inflammation and cancer initiation and progression are linked. Interleukin-6 (IL-6) is a pleiotropic inflammatory cytokine with described cancer stimulatory and also cancer inhibitory properties. The study's aim was to assess the potential of circulating IL-6 as a prognostic indicator…

Because the University of Colorado (CU) School of Nursing Nursing Doctorate (ND) Program initiated an innovative nursing educational reform, emerging program evaluation challenges were addressed to ensure successful implementation and program quality. The study's purpose was to evaluate the effectiveness of the ND prof…

BACKGROUND: Postpartum sexual activity is frequently resumed earlier than is recommended in low-resource settings, endangering the health of the mother. Postpartum decision-making is heavily impacted by partner-related and cultural factors, especially in rural and patriarchal environments. Research that has been publis…

Population-based studies suggest the association between exposures to bisphenol A (BPA) and obesity. However, no human studies are available that link exposures to chlorinated derivatives of BPA with obesity biomarkers. The objective of this exploratory post hoc analysis of our cross-sectional study's dataset was to ev…

Microbiota composition in breast milk affects intestinal and respiratory microbiota colonization and the mucosal immune system's development in infants. The metabolomic content of breast milk is thought to interact with the microbiota and may influence developing infant immunity. One hundred seven Gambian mothers and t…

Japan has the world's fastest-aging population. The number of older adults living alone has increased rapidly; however, the number of people waiting for nursing care facilities is high, especially in urban areas, and home care is unavoidable. Few studies have focused on older adults living alone who require nursing car…

PURPOSE: To report the extent (how many), range (variation) and nature (qualities) of rehabilitation interventions for children living with HIV. METHOD: Electronic databases, reference lists of included articles, and grey literature were searched. Title and abstract and full text review were completed independently by…

This article critically appraises the study by Nakken et al., "Duration of Current Statin Use and Amyotrophic Lateral Sclerosis (ALS) Risk." Previous observational studies and Mendelian randomization studies examining statin use and ALS risk have reported mixed results. Millions of adults receive statins for cardiovasc…

The Mental Health Act 1983 gives the police the power to remove those persons who appear to be mentally disordered from a public place to a place of safety. Previous studies have shown conflicting results concerning its use and there have not been any previous studies in a rural area. This study is a prospective survey…

BACKGROUND: Health care professionals underestimate the recognition of delirium in emergency departments (EDs). In these settings, between 57% and 83% of cases of delirium go undetected. When delirium occurs, it causes an increase in the length of hospitalization, readmissions within 30 days, and mortality. No studies…

UNLABELLED: The study sought to examine the impact of coronavirus disease 2019 on the socioeconomic livelihoods of rural communities by focusing on the Good Hope community under Mbashe Municipality. A qualitative research methodology was employed through in-depth interviews and focus group discussions. The study sought…

Identifying the root causes of accidents and analyzing their causal relationships is a fundamental step in designing effective preventive strategies. This study aimed to uncover the root causes of mining accidents and determine the interactions among them from the perspectives of workers, supervisors, and safety office…

INTRODUCTION: Recruiting participants into research trials is essential for the advancement of scientific knowledge that depends on clinical research studies. For the field of exercise and physical activity, there is an added difficulty in recruiting participants because participants must be willing to participate in a…

AIMS: Colorectal cancer (CRC) is the third most common malignancy worldwide. Accurate pathological diagnosis and predictive abilities for treatment response and prognosis are crucial for patients with CRC. This study aims to analyse the expressions of p21 and EGFR in CRC and their relationships with clinicopathological…

Deep infiltrative endometriosis (DIE) is an enigmatic disease that typically impacts the rectovaginal septum, uterosacral ligaments, pararectal space, and vesicouterine fold but can involve the rectum, sigma, ileum, ureters, diaphragm, and other less common sites. Surgery is the treatment of choice because medical mana…

Although critical analysis of survey research is limited when reviewers and readers cannot view a study's questionnaire, access to novel questionnaires used in published research has not been systematically examined. The authors identified publications reporting the results of novel questionnaires in three medical jour…

BACKGROUND: Elevated depressive symptoms are associated with impairments, reduced quality of life, and societal economic burden. A well-established stress-vulnerability model explaining depressive symptoms is Beck's cognitive theory (Beck, 1976). An independent line of research demonstrated that a person's perception o…

During the study's first stage, 284 homeless people from crisis and long-term accommodation sites were surveyed using stratified, systematic sampling. The second stage involved a survey of a convenience sample of 100 homeless people from squats and the streets. Participants completed a questionnaire, Mantoux testing wa…

Pubertal development has been separately linked to adolescents' sleep problems and larger family functioning, but research connecting these inter-related processes remains sparse. This study aimed to examine how pubertal status and tempo were related to early adolescents' sleep and their family functioning. Using longi…

As COVID-19 spread rapidly during the early months of the pandemic, many communities around the globe anxiously waited for a vaccine. At the start of the pandemic, it was widely believed that Africa would be a significant source of infection, and thus, vaccinating African communities became a primary goal among local a…