2,644 papers found

The circular code theory proposes that genes are constituted of two trinucleotide codes: the classical genetic code with 61 trinucleotides for coding the 20 amino acids (except the three stop codons {TAA,TAG,TGA}) and a circular code based on 20 trinucleotides for retrieving, maintaining and synchronizing the reading f…

OBJECTIVES: We aimed to develop and evaluate an algorithm for automatically screening citations when updating living network meta-analysis (NMA). STUDY DESIGN AND SETTING: Our algorithm learns from the initial screening of citations conducted when creating an NMA to automatically identify eligible citations (i.e., nee…

Syndromic surveillance systems that incorporate electronic free-text data have primarily focused on extracting concepts of interest from chief complaint text, emergency department visit notes, and nurse triage notes. Due to availability and access, there has been limited work in the area of surveilling the full text of…

Text generative models trained via maximum likelihood estimation (MLE) suffer from the notorious exposure bias problem, and generative adversarial networks (GANs) are shown to have potential to tackle this problem. The existing language GANs adopt estimators, such as REINFORCE or continuous relaxations to model word pr…

Here, we illustrate the clinical and technical implementation of interoperable health data for direct care from the viewpoint of practicing clinicians using examples from primary care. Interoperability allows people involved in the provision and receipt of care to seamlessly exchange and use the coded, free text and do…

BACKGROUND: The presence of dental caries impacts on children's daily lives, particularly among those living in deprived areas. There are successful interventions across the United Kingdom for young children based on toothbrushing with fluoride toothpaste. However, evidence is lacking for oral health improvement progra…

Using a continuum evolution equation, we model the growth and evolution of quantum dots in the heteroepitaxial Ge on Si(0 0 1) system in a molecular beam epitaxy unit. We formulate our model in terms of evolution due to deposition, and due to surface diffusion which is governed by a free energy. This free…

A variety of diseases, hereditary conditions, toxins and drugs may cause thrombocytopenia. Thrombocytopenia induced by ceftriaxone has been rarely reported. In this case, ceftriaxone-induced thrombocytopenia is presented in a 2-year-old girl due to rare presentation (Ref. 10). Full Text in free PDF www.bmj.sk.

AIMS: The NHS Stop Smoking Service (NHS-SSS) helps approximately half its clients to quit for 4 weeks. However, most initially successful quitters relapse within 6 months. Short message service (SMS) texting has been shown to facilitate stopping smoking. We describe the development, implementation and subsequent evalua…

BACKGROUND: In patients with hypoalbuminemia after craniotomy, total serum concentrations of valproic acid (VPA) may provide poor clinical insights, owing to saturated protein binding and increased unbound fractions. However, very few clinical laboratories routinely analyze free concentrations of the drug. The aim of t…

Quality improvement activities in healthcare are limited by the substantial time burden associated with manual clinical text review. To address this limitation within an established hospital discharge summary improvement project, we aimed to automate quality monitoring using large language models. Models were trained t…

The oxygen uptake efficiency slope (OUES) is a well-established substitute for maximum oxygen uptake ((Equation is included in full-text article.)O2 max) in submaximal exercise effort among adolescents and adults. Few studies have analyzed the exercise capacity (EC) and OUES of children aged 4 to 6 (preschoolers). Body…

PURPOSE: The purpose of this study was to enhance our understanding of factors that influence help-seeking in people with inflammatory bowel disease (IBD)-related fecal incontinence (FI), and their needs or desire for continence services. SUBJECTS AND SETTING: We conducted a survey of FI in community-dwelling people w…

BACKGROUND: Evidence suggests that modifiable risk factors which can be targeted by prevention are vascular diseases, such as diabetes, midlife hypertension (HTN), midlife obesity, midlife cholesterol, mid- and late-life depression as well as lifestyle factors such as smoking, physical inactivity, and poor diet. METHO…

BACKGROUND AND AIM: We analyzed an inclusive gradient boosting model to predict hospital admission from the emergency department (ED) at different time points. We compared its results to multiple models built exclusively at each time point. METHODS: This retrospective multisite study utilized ED data from the Mount Si…

OBJECTIVE: The research describes an extensible method of evaluating and cancelling electronic journals during a budget shortfall and evaluates implications for interlibrary loan (ILL) and user satisfaction. METHODS: We calculated cost per use for cancellable electronic journal subscriptions (n=533) from the 2013 cale…

We report a rare case of a patient with late onset of Chiari I malformation with associated syringomyelia that was successfully treated with foramen magnum decompression. Our patient is presenting initially with vertigo and gradual weakening of the left-hand gross motor ability, gradual hypesthesia. Magnetic resonance…

A thorough understanding of the longitudinal phase space (LPS) of the electron beam is of great advantage to any modern linear accelerator (linac), and of critical importance for operating a free electron laser (FEL). While a transverse deflecting structure (TDS) allows full characterization of a beam's LPS, measuremen…

BACKGROUND: Every year the scientific sessions of Annual National Conference of Indian Psychiatric Society (ANCIPS) are marked by presentation of free papers, posters, and award paper sessions, which are usually meant for presentation of new research which is not yet published. Hence, it is expected that these papers w…

BACKGROUND: Low rates of adherence to artemisinin-based combination therapy (ACT) regimens increase the risk of treatment failure and may lead to drug resistance, threatening the sustainability of current anti-malarial efforts. We assessed the impact of text message reminders on adherence to ACT regimens. METHODS: Hea…