98,289 papers found

PURPOSE: Systemic therapy use in the last 30 days of life (DOL) for patients with advanced cancer is a low-value medical practice. We hypothesized that systemic therapy use in the last 30 DOL increased after approval of antiprogrammed cell death protein 1 immune checkpoint inhibitors (ICIs) and has contributed to incre…

OBJECTIVES: To examine the pattern of attendance at sexually transmitted disease (STD) clinics in Britain. To compare the demographic characteristics, behaviours and attitudes of STD clinic attenders with those of non-attenders, and to assess the extent to which STD clinics are used by those with high-risk sexual lifes…

Single-room ward design has previously been associated with increased risk of inpatient falls and adverse outcomes. However, following quality initiatives, the incidence of inpatient falls has shown a sustained reduction. Benefits have also been observed in the reduction of hip fractures. However, one-year mortality tr…

The myelodysplastic syndromes (MDS) have attracted great interest during the last decade. Unfortunately there is not much material published concerning the incidence of these conditions. We present epidemiologic data on MDS based on case registration of patients in a well-defined population and as a comparison similar…

UNLABELLED: Cancer registry data obtained from the Kuwait Cancer Registry at Kuwait Cancer Control Center (KCCC) of Ministry of Health, State of Kuwait. The data covers the years 1974 to 2007. AIM OF THIS STUDY: was to estimate the magnitude of the cancer problem in Kuwait over the period 1974-2007. MATERIALS AND MET…

AIMS: Evaluation of pattern of recurrences of 290 patients with an Ewing's sarcoma family tumor (ESFT), who relapsed after adjuvant or neoadjuvant chemotherapy. METHODS: Retrospective analysis at a median follow-up of 16.6 years (range: 5-32) from the primary therapy. RESULTS: There were 378 recurrences, treated by s…

INTRODUCTION: Health needs increase in older age. This translates into higher healthcare utilisation and expenditure compared to any other age group. Much of this is driven by frailty and multimorbidity. Many older people spend their last days in hospital. The aim of this study was to explore the utilisation of healthc…

PURPOSE: To investigate the 2-year healing rate of macular edema (ME) secondary to branch retinal vein occlusion (BRVO) treated initially with intravitreal ranibizumab (IVR) and later combined with other treatment as needed, and the characteristics of refractory cases. METHODS: 130 patients (130 eyes) with BRVO-ME who…

OBJECTIVE: This study aimed to compare the curative efficacy of hemivertebra resectionthe posterior approach assisted with unilateral and bilateral internal fixation in the treatment of congenital scoliosis (CS). METHODS: In this study, 29 children (15 males and 14 females), who underwent hemivertebra resectionthe pos…

BACKGROUND: Data on the temporal trends in ideal cardiovascular health (CVH) as well as on their association with subclinical/overt cardiovascular disease (CVD) and death are limited. METHODS AND RESULTS: This study included 3460 participants attending ≥1 of 4 consecutive exams of the Framingham Heart Study (19…

The incidence of new cases of idiopathic pulmonary arterial hypertension(IPAH) is reported to be one or two per 1,000,000 of the population. The 5-year survival of patients with IPAH has improved from about 30% to 60% in Japan. The estimated prevalence of IPAH is now 10 to 20 per 1,000,000. The actual reported prevalen…

Four magnetic profiles across the Pacific-Antarctic Ridge reveal magnetic anomalies that show trends parallel with the ridge axis and symmetry about the ridge axis. The distribution of bodies that could cause these anomalies supports the Vine and Matthews hypothesis for the generation of patterns of magnetic anomalies…

OBJECTIVES: To monitor trends in under-reporting of smoking in Italy over the last two decades. METHODS: A total of 9 representative population-based surveys on smoking conducted in Italy in 1990 and annually between 2001 and 2008, covering 26,397 individuals, were studied. The number of cigarettes per day per person…

Recent paleoclimate reconstructions have challenged the traditional view that Northern Hemisphere insolation and associated feedbacks drove synchronous global climate and ice-sheet volume during the last glacial cycle. Here we focus on the response of the Patagonian Ice Sheet, and demonstrate that its maximum expansion…

BACKGROUND: This study examines last dental visit (visiting within the last 12 months, having a last visit 5 or more years ago, attending a private dental practice) and usual visit (usually visiting for a check-up, having a dentist they usually attend). METHODS: Explanatory variables include age, gender, region,…

8679 post mortem dissections have been performed in the Institute during the rescent 25 years; 563 of them have been cases of poisoning (=6.5% of totality). They were grouped for the years 1950--1965 and 1966--1975. Suicidal poisoning showed an increasing, poisoning in children a decreasing tendency during the last 25…

INTRODUCTION: Colorectal cancer (CRC) is the second leading cause of cancer deaths in the United States and the third most common malignant neoplasm worldwide. Chinese Americans are one of the ethnic minority groups who have the lowest rates of CRC screening. The purpose of this study was to describe CRC screening amon…

A procedure for assessing birth spacing goals, an important component of fertility preferences, is proposed and applied to 1993 Costa Rican data. Based on a reverse or backward survival analysis, preferred birth intervals are estimated to range between 3.5 and 4.5 years (1.5 years for the interval union to first birth)…

BACKGROUND: The long-term outcome of surgery for adolescent idiopathic scoliosis (AIS) using segmental pedicle screw constructs is sparsely described in the scientific literature. METHODS: Retrospective case series of 120 consecutive patients operated for AIS using segmental pedicle screw constructs. Age between 11 an…

Ten magnetic profiles across the mid-Atlantic ridge near 27 degrees N show trends that are parallel to the ridge axis and symmetrical about the ridge axis. The configuration of magnetic bodies that could account for the pattern supports the Vine and Matthews hypothesis for the origin of magnetic anomalies over oceanic…