5,081,904 papers found

AIM: Isolated colon lipomas are rare benign tumors. We herein conducted a systematic review of the literature to identify clinical characteristic, diagnostic and treatment options. MATERIALS AND METHODS: A search for relevant studies was conducted in Scopus, Embase and Medline databases until the end of May 2014. The…

BACKGROUND: Gynecologic cancers are associated with long-term physical and psychological challenges. Physical activity (PA) and exercise are increasingly recognized as important components of cancer care. However, no umbrella review has synthesized evidence across gynecologic cancers. This review aims to evaluate the e…

INTRODUCTION: There is a growing clinical recognition that a significant proportion of patients with gender dysphoria have concurrent autism spectrum disorder (ASD). AIM: The purpose of this review is to systematically appraise the current literature regarding the co-occurrence of gender dysphoria and ASD. METHODS: A…

BACKGROUND: Multiple review systems have been established within medicine and psychology to evaluate and disseminate research findings to clinical practice. PURPOSE: Within this article, five evidence-based review systems are reviewed to inform the development or the use of an evidence review system for the behavioral…

A number of new biological markers are being studied as predictors of disease or adverse medical events among those who already have a disease. Systematic reviews of this growing literature can help determine whether the available evidence supports use of a new biomarker as a prognostic test that can more accurately pl…

BACKGROUND: Cultural and linguistic minorities are at a higher risk of poorer health, poorer health outcomes, and poorer quality of care, in part due to a lack of access to healthcare services. Inequities in access to healthcare services have been found in several Deaf populations and are associated with poorer physica…

Reporting guidelines can be used to encourage standardised and comprehensive reporting of health research. In light of the global commitment to health equity, we have previously developed and published a reporting guideline for equity-focused systematic reviews (PRISMA-E 2012). The objectives of this study were to expl…

This article is part of the series "How to prepare a systematic review of economic evaluations (EES) for informing evidence-based healthcare decisions", in which a five-step approach is proposed. Areas covered: This paper focuses on the selection of relevant databases and developing a search strategy for detecting EEs,…

Persistent androgen signaling is functionally significant in castration-resistant prostate cancer (CRPC) and it is actually considered a validated therapeutic target. Residual intra-tumoral androgens compensate for the effects of androgen ablation, activating the androgen receptor (AR), AR-mediated gene expression and…

BACKGROUND: Systematic reviews cataloguing the barriers to and facilitators of various outcomes are increasingly popular, despite criticisms of this type of review on philosophical, methodological, and practical grounds. The aims of this review are to appraise, analyze, and discuss the reporting and synthesis practices…

BACKGROUND: This study aims to synthesize knowledge about the role of the public's participation in the definition, prioritization, rationalization, monitoring or control of policies, plans, governance, investment/disinvestment, and design of health services. METHODS: Review of review articles (narrative or systematic…

STUDY DESIGN: Method guidelines for systematic reviews of trials of treatments for neck and back pain. OBJECTIVE: To help review authors design, conduct and report systematic reviews of trials in this field. SUMMARY OF BACKGROUND DATA: In 1997, the Cochrane Back Review Group published Method Guidelines for Systematic…

INTRODUCTION: Suicide remains a critical global public health issue, with approximately 800,000 deaths annually. Despite various prevention efforts, suicide rates are rising, highlighting the need for more effective strategies. Traditional suicide risk assessment methods often fall short in accuracy and predictive capa…

BACKGROUND: Nurses leaving their jobs and the profession are an issue of international concern, with supply-demand gaps for nurses reported to be widening. There is a large body of existing literature, much of which is already in review form. In order to advance the usefulness of the literature for nurse and human reso…

BACKGROUND: Systematic reviews of literature are increasingly important in healthcare. While reviewers are expected to follow reporting guidelines, inconsistencies may be observed in presentation of reviews, potentially detracting from the credibility of findings. Predetermined eligibility criteria are fundamental to t…

AIMS AND OBJECTIVES: To analyse systematic review articles published in the top 10 nursing journals to determine the quality of the methods employed within them. BACKGROUND: Systematic review is defined as a scientific research method that synthesises high-quality scientific knowledge on a given topic. The number of s…

INTRODUCTION: Individual participant data (IPD) systematic reviews and meta-analyses are often considered to be the gold standard for meta-analysis. In the ten years since the first review into the methodology and reporting practice of IPD reviews was published much has changed in the field. This paper investigates cur…

The objective of the study was to evaluate and summarize the evidence from systematic reviews and meta-analyses regarding the efficacy and safety of Aidi injection combined with chemotherapy in the treatment of cancer patients. PubMed, EMBASE, Web of Science, Cochrane Library, China National Knowledge Infrastructure, C…

Motivation is a well-established predictor of recovery for addictive behaviors. Treatments aimed at changing substance use and gambling frequently employ motivational enhancing strategies, based in the principles of Motivational Interviewing (MI). Evidence for these approaches across addictive behaviors does not always…