375,956 papers found

BACKGROUND: India bears a heavy burden of iron deficiency anemia (IDA), affecting nearly 50% of the population and contributing to adverse pregnancy outcomes, accounting for 20% of maternal deaths. While IDA continues to be a major health issue in India, there is a lack of comparative data on the efficacy of Ayurvedic…

Epoxy resin-based sealers (ERBSs) are well-established in endodontics. This review evaluated whether the incorporation of nanoparticles (NP) alters their standardized physicochemical properties and further examined potential dose-response effects and the existence of a minimum effective NP weight percentage. PubMed, Sc…

This meta-analysis aimed to evaluate the efficacy and safety of various antibiotics used as definitive therapy for bacteremia caused by AmpC-producing bacteria. MEDLINE via PubMed, the Cochrane Central Register of Controlled Trials, and the ClinicalTrials.gov website were comprehensively searched to identify all releva…

OBJECTIVE: To employ a network meta-analysis methodology to compare the effects of different lifestyle interventions on weight control and blood pressure in hypertensive patients, thereby providing evidence-based guidance for nursing practice. METHODS: A systematic search was conducted across PubMed, Web of Science, t…

Delirium is a common, critical condition in adults receiving care in intensive care units, requiring effective screening tools for early detection. To systematically compare the diagnostic performance of delirium screening tools for adults receiving care in ICUs, we conducted a comprehensive search across nine database…

OBJECTIVE: Stroke frequently results in lower-limb dysfunction, severely limiting independence. This study compared the effectiveness of resistance training alone and resistance training combined with other rehabilitation modalities in improving poststroke lower-limb function. DESIGN: A systematic review and Bayesian…

Despite several small comparative clinical trials, controversy persists over the best choice of antimicrobial therapy for penetrating abdominal trauma. Some still question whether single drug regimens are as effective as the traditional combinations containing an aminoglycoside. A meta-analysis was performed to address…

OBJECTIVES: To quantitatively analyze the dentoskeletal effect of various maxillary expansion appliances on growing children and adolescents with transverse maxillary arch deficiency three-dimensionally and to establish the direct and indirect relationship of various maxillary expansion appliances. MATERIALS AND METHO…

BACKGROUND: Diabetic Foot Ulcers are a serious complication of diabetes, and the clinical treatment is challenging. In this study, network meta-analysis was used to evaluate the effect of different non-drug interventions on Diabetic Foot Ulcer healing and provide evidence to support clinical decision-making. METHODS:…

A meta-analysis of 10 randomized trials comparing steroid therapy with placebo or abstention was performed. Trials were pooled for severity of acute alcoholic hepatitis and time of analysis. Papers with survival analyses at one and three months were included. The robustness of this meta-analysis was analysed after excl…

PURPOSE: It is not clear whether indirect laryngoscopes are superior to direct laryngoscopes for nasotracheal intubation and which laryngoscopes are better for nasotracheal intubation. We sought to undertake a ranking of the effectiveness of intubation devices in patients undergoing nasotracheal intubation. METHODS: W…

Model-based meta-analysis (MBMA) utilizes aggregate data (AD) and allows integration of information from multiple studies, which may provide more statistical power to detect clinically relevant treatment effects than an individual randomized controlled trial alone. Access to individual patient data (IPD) is often limit…

BACKGROUND: Loneliness and social isolation are prevalent and persistent in cancer patients, affecting their psychosocial adjustment. Non-pharmacological interventions have been shown to be effective in previous studies; however, the most effective types of non-pharmacological interventions for this population remain u…

OBJECTIVE: To evaluate the risk of major injuries associated with Veress, open (Hasson), direct and optical abdominal entry methods in laparoscopy. METHODS: Network meta-analysis was performed using penalized logistic regression. Pairwise meta-analysis was carried-out using Bayesian binomial-normal hierarchical models…

A series of 1153 fine-needle aspiration biopsies (FNAB) of breast masses obtained during the period 1985 to 1988 in one institution was examined. The following diagnostic accuracy values were found: sensitivity, 93.0%; specificity, 92.4%; predictive positive value, 93.7%; and efficiency, 92.8%. These results were compa…

This study aimed to assess, compare, and rank the effects of different behavioral interventions on key cardiovascular risk factors in adults with type 2 diabetes. We searched PubMed, Scopus, and Web of Science up to March 2025. A random-effects network meta-analysis with a Frequentist framework was conducted to estimat…

BACKGROUND: To compare the effects of different digitally and remotely deliveredexercise interventions on glycated hemoglobin (HbA1c) in adults with type 2diabetes mellitus (T2DM) using a network meta-analysis (NMA), and to clarifythe relative effectiveness of distinct delivery models. METHODS: A systematic review and…

BACKGROUND: This study aimed to evaluate the effectiveness of non-pharmacological interventions for improving sleep quality in patients with multiple sclerosis (MS) using a systematic review and network meta-analysis. METHOD: Randomized controlled trials examining the effects of non-pharmacological interventions on sl…

INTRODUCTION: Managing postoperative pain in patients following bariatric surgery is challenging. Although transversus abdominis plane block (TAPB) and erector spinae plane block (ESPB) have proved effective for pain relief, the analgesic efficacy between them remains controversial. This network meta-analysis was condu…

Depression, a condition severely endangering individual health and societal progress, is projected by the WHO to become the leading global disease burden by 2030. Currently, three categories of therapies are employed in clinical practice: psychotherapy, pharmacotherapy, and physical therapy. The treatment strategies ut…