5,042,053 papers found

OBJECTIVE: The current systematic review summarizes reviews on effects of formalized peer support work in clinical psychiatric settings in order to obtain an up-to-date picture of the current state of evidence. METHODS: Search in five electronic databases for relevant literature reviews regarding effects of peer suppo…

INTRODUCTION: There is a growing clinical recognition that a significant proportion of patients with gender dysphoria have concurrent autism spectrum disorder (ASD). AIM: The purpose of this review is to systematically appraise the current literature regarding the co-occurrence of gender dysphoria and ASD. METHODS: A…

The capability of Large Language Models (LLMs) to support and facilitate research activities has sparked growing interest in their integration into scientific workflows. This paper aims to evaluate and compare against human researchers the performance of 6 different LLMs in conducting the various tasks necessary to pro…

BACKGROUND: Telemetry monitoring in patients with low-risk chest pain continues to be highly used despite a 2011 literature review and recommendations by the Clinical Practice Committee (CPC) of the American Academy of Emergency Medicine that did not find quality data to support its use. OBJECTIVE: To update the medic…

AIM: Isolated colon lipomas are rare benign tumors. We herein conducted a systematic review of the literature to identify clinical characteristic, diagnostic and treatment options. MATERIALS AND METHODS: A search for relevant studies was conducted in Scopus, Embase and Medline databases until the end of May 2014. The…

INTRODUCTION: Outcome measures are being widely used by health services to assess the quality of health care. It is important to have a battery of useful performance indicators with high validity and feasibility. Thus, the objective of this study is to perform a review of reviews in order to identify outcome indicators…

Persistent androgen signaling is functionally significant in castration-resistant prostate cancer (CRPC) and it is actually considered a validated therapeutic target. Residual intra-tumoral androgens compensate for the effects of androgen ablation, activating the androgen receptor (AR), AR-mediated gene expression and…

OBJECTIVES: To describe and compare, through a scoping review, emerging knowledge synthesis methods for integrating qualitative and quantitative evidence in health care, in terms of expertise required, similarities, differences, strengths, limitations, and steps involved in using the methods. STUDY DESIGN AND SETTING:…

AIMS AND OBJECTIVES: To analyse systematic review articles published in the top 10 nursing journals to determine the quality of the methods employed within them. BACKGROUND: Systematic review is defined as a scientific research method that synthesises high-quality scientific knowledge on a given topic. The number of s…

INTRODUCTION: Individual participant data (IPD) systematic reviews and meta-analyses are often considered to be the gold standard for meta-analysis. In the ten years since the first review into the methodology and reporting practice of IPD reviews was published much has changed in the field. This paper investigates cur…

Systematic review is typically viewed in the health sciences as the most objective--that is, rigorous, transparent, and reproducible--method for summarizing the results of research. Yet, recent scholarship has shown systematic review to involve feats of interpretation producing less certain, albeit valuable, results. W…

Systematic review (SR) and meta-analysis (MA) have potential to contribute substantially to environmental health (EH) risk assessment and policy-making, provided study questions are clear and methods sound. We undertook a systematic review of the published epidemiological literature for studies using both SR and MA exa…

This study aimed to systematically verify the available systematic reviews and meta-analyses of Low-level laser therapy (LLLT) in diabetic foot ulcer (DFUs) to identify the effects and optimal parameters of LLLT in the management of DFUs. This umbrella review was written according to the Preferred Reporting Items for S…

BACKGROUND: Understanding which factors influence participation in physical activity is important to improve the public health. The aim of the present review of reviews was to summarize and present updated evidence on personal and environmental factors associated with physical activity. METHODS: MEDLINE and EMBASE wer…

OBJECTIVES: To review the evidence on public involvement in the systematic review process in health and social care; to examine the different methods, levels and stages of involving the public; to synthesise the contributions of the public, as well as the identified tensions, facilitating strategies and recommendations…

Dietary supplementation with omega-3 polyunsaturated fatty acids from fish and plant sources is commonly prescribed as a non-farmacological alternative to improve brain functions and slow down the progression of dementia. This use is mostly based on findings of preclinical studies which established the role of omega-3…

Suicide is a major public health concern and, with recent societal changes, such as economic and technological changes, there may be emerging protective factors that mitigate suicide risk that are unrecognized in emergency healthcare. This systematic review aims to identify protective factors for suicide that can feasi…

OBJECTIVES: To identify and appraise empirical studies on publication and related biases published since 1998; to assess methods to deal with publication and related biases; and to examine, in a random sample of published systematic reviews, measures taken to prevent, reduce and detect dissemination bias. DATA SOURCES…

OBJECTIVE: To demonstrate the application of the modified Ottawa method by establishing the update need of a systematic review with focus on the caries preventive effect of GIC versus resin pit and fissure sealants; to answer the question as to whether the existing conclusions of this systematic review are still curren…

OBJECTIVE: To evaluate the effectiveness of brief interventions in the primary health care setting to decrease alcohol consumption in non-alcoholic adult drinkers. METHOD: Systematic review of systematic reviews and meta-analyses of randomized clinical trials published in English and Spanish and indexed in EMBASE, MED…