44,715 papers found

The most common manifestations characterizing Sjögren's disease (SjD) are extensive ocular and oral dryness due to decreased lacrimal (keratoconjunctivitis sicca) and salivary gland function (xerostomia). Another hallmark of SjD is the presence of autoantibodies. Acinar cells in the exocrine glands express muscari…

PURPOSE: Problematic Internet Use (PIU) has been associated with emotional difficulties in childhood and adolescence. However, the directionality of this relationship remains unclear due to the lack of terminological consensus and wide variability in prevalence estimates. This systematic review aims to synthesize the l…

BACKGROUND & OBJECTIVE: The added value of lymphadenectomy is a widely debated topic, especially in cases of early-stage epithelial ovarian cancer (EOC). We present robust evidence through an updated systematic review and meta-analysis regarding the effects of lymphadenectomy on overall survival (OS) and progression-fr…

AIM: This systematic review aims to evaluate the clinical applications of infrared thermography (IRT) in rheumatic diseases (RDs), focusing on its potential as a non-invasive, cost-effective, and reliable tool for diagnosis, monitoring, and treatment to improve patient outcomes. METHODS: A systematic literature review…

BACKGROUND: Bioethics is fundamental in healthcare, guiding ethical decision-making and patient care. Translational bioethics (TB) aims to bridge the gap between ethical theories and real-world practice, including nursing. However, the concept of TB has not been clearly examined yet. Therefore, this concept analysis wa…

Benzodiazepines (BZDs) are widely used anxiolytics for treating various psychiatric conditions and for procedures requiring conscious sedation. Despite their therapeutic benefits, there is concern about their paradoxical effects, particularly the potential increase in suicidal ideation and suicide completion. This syst…

BACKGROUND: In the elderly, diagnosing and treating functional dyspepsia may be more challenging. The objectives of the study were to evaluate the prevalence and association of functional dyspepsia in adult individuals and elderly populations (especially ≥64 years) in the year 2024-2025 literature availab…

AIMS: The views of parents/caregivers about food programs in schools internationally is not well understood. This review aimed to synthesise what parents/caregivers identify as the key features of school food programs and their perspectives of these programs globally. METHODS: A mixed papers review was undertaken with…

BACKGROUND: The occupational hazards of glutaraldehyde are well known; the possibility of harm to the patients has been highlighted in the form of isolated reports only. OBJECTIVE: To synthesize evidence for contact mucosal injury or injury due to intraperitoneal instillation of glutaraldehyde following its use during…

OBJECTIVES: This study aimed to systematically categorize the available literature and offer a comprehensive overview of artificial neural network (ANN) prediction models in prosthodontics. Specifically, the present research introduces a systematic analysis of ANN aims, data, architectures, evaluation metrics, and limi…

Functional dyspepsia (FD) is a prevalent chronic digestive disorder that significantly impacts patients' quality of life. Sleep disturbance (SD) is common among FD patients, yet the relationship between SD and FD remains poorly characterized. This systematic review explores the bidirectional relationship between FD and…

INTRODUCTION: Wounds are invariably dressed postoperatively but the evidence for the timing of dressing changes is limited. This meta-analysis evaluated whether the relative risk of wound infection varies depending on when dressings are changed. METHODS: A frequentist random-effects network meta-analysis was conducted…

INTRODUCTION: Traumatic brain injury (TBI) refers to damage to brain tissue by mechanical or blunt force via trauma. TBI is often associated with impaired cognitive abilities, like difficulties in memory, learning, attention, and other higher brain functions, that typically remain for years after the injury. Lithium is…

Malnutrition among in-school children is a complex issue influenced by socio-economic, environmental, and health-related factors, posing significant challenges to their well-being and educational trajectories in developing countries. This review synthesized evidence on the multifaceted aspects of child malnutrition wit…

PURPOSE: Gut barrier dysfunction is a pivotal pathophysiological alteration in cirrhosis and end-stage liver disease, which is further aggravated during and after the operational procedures for liver transplantation (LT). In this review, we analyze the multifactorial disruption of all major levels of defense of the gut…

PURPOSE: To summarize the mechanism and the clinical applications of subthreshold laser (STL) in retinal practice. Subthreshold or "non-destructive" laser includes all types of laser treatments that produce minimal or no damage to the tissues and no visible signs after application. METHODS: A descriptive review of art…

Stroke remains one of the world's greatest causes of disability and death. Insulin resistance (IR) impairs insulin's beneficial effects on the brain and can change the course of illness in post-stroke patients. This review aims to find sufficient evidence to support the causal association of IR in ischemic stroke and w…

Neuralgia is characterized by chronic pain resulting from damage or diseases in the somatosensory system, including nerves responsible for transmitting sensory information. Current treatments for neuropathic pain, which is a type of neuralgia, have limited success rates and can cause unwanted side effects. Since 1…

BACKGROUND: This systematic review and meta-analysis aimed to synthesize the evidence on the preoperative characteristics, operative outcomes, and postoperative complications of simple and complex segmentectomy for lung cancer. METHODS: A systematic review of EMBASE (through Ovid), MEDLINE (via PubMed), and Cochrane C…

OBJECTIVE: This article aims to provide an evaluation of the psychometric properties of the instruments of oral health literacy in adults. METHODS: An electronic search for instrument studies was performed in the PubMed, PubMed Central, ScienceDirect, Scopus, EMBASE, and PsycINFO databases to find articles published u…