11,356,020 papers found

This study assessed whether multimodal pain modalities are effective at decreasing narcotic utilization following ankle fracture surgery. A retrospective chart review of opioid-naive patients aged 18 - 65 undergoing ankle fracture surgery was performed. Patients were prescribed a multimodal pain regimen of acetaminophe…

This secondary analysis used data collected for the Korean Longitudinal Study of Aging from 2006 to 2018 to examine changes in life satisfaction among middle-aged adults living alone in South Korea. Individuals who were over 45 years of age, lived alone at the time of the first data collection wave, and responded at le…

Social frailty among older adults has become a growing concern from a public health perspective in the context of the coronavirus disease 2019 (COVID-19) pandemic. This study's aim was to investigate the influence of various aspects of social frailty in community-dwelling older adults during the COVID-19 pandemic. This…

Guided by the Theory of Planned Behaviour, this study investigates littering attitudes, social norms, and perceived behavioural control as predictors of the intention to prevent littering and actual littering prevention behaviour among residents of a developing country (Nigeria). The study employed a survey questionnai…

Virtual learning resources (VLRs) developed using immersive technologies like virtual reality are becoming popular in medical education, particularly in anatomy. However, if VLRs are going to be more widely adopted, it is important that they are designed appropriately. The overarching aim of this study was to propose g…

Thus far, data on sleep disorders among prison officers (POs) have been scarce. Research allows us to relate this problem to occupational stress, which POs experience every day. The aim of the current study was to analyze the scale, predictors, and impact of select factors on the relationship between insomnia and occup…

This study's objectives were, first, to examine the association between social engagement and the odds of taking hypertensive medications and treatment among adults in China; and second, to explore the lifestyle and psychological mechanisms underlying this association. Data were from the WHO Study on Global AGEing and…

The PLATO study evaluated the efficacy of adding ticagrelor, instead of clopidogrel, to aspirin in patients with acute coronary syndrome, which showed surprisingly positive results making the drug acceptable to regulatory agencies and specialty societies worldwide. Notwithstanding the aforementioned success, contradict…

BACKGROUND: End-of-Life Nursing Education Consortium (ELNEC) train-the-trainer workshops prepare participants to teach ELNEC content to others. In 2010, researchers in Japan developed and validated the End-of-Life Nursing Education Questionnaire (ELNEQ) to measure the impact of ELNEC workshops on participants' readines…

PURPOSE. Investigate relations between demographic characteristics and submission method, Internet or paper, when physical activity behaviors are reported. DESIGN. Observational. SETTING . Metropolitan. SUBJECTS. Adult women (N  =  918) observed weekly for 2 years (total number of weekly reports, 44,963).…

Communities That Care (CTC) is a prevention system designed to reduce adolescent substance use and delinquency through the selection of effective preventive interventions tailored to a community's specific profile of risk and protection. A community-randomized trial of CTC, the Community Youth Development Study, is cur…

The purpose of this evaluative study was to determine if elderly patients' mental health assessment scores improved after receiving specialized inpatient treatment. A random sample of 106 cases was drawn from existing medical records of patients treated during a 2-year time period in a comprehensive geropsychiatric inp…

OBJECTIVE: The aim of this study was to assess risk for developed active tuberculosis in HIV infected IDU oblation and relate with immunodeficiency degree. METHODS: Longitudinal follow-up was realized, the period of study was 9 years, in HIV seropositive IDU patients. Control group was HIV seronegative IDU. CD4+ lymph…

BACKGROUND: Students remain in a sedentary position inside classrooms for 60% to 80% of their school day. As such, research has associated students' prolonged seated posture on school furniture with their discomfort and musculoskeletal pain. The correlation between the shape of the seat surface and the zones of the bod…

BACKGROUND: Interleukin (IL)-23-induced T helper (Th) 17 pathway is involved in the pathogenesis of periodontal disease. This study's aim is to determine levels of IL-1β, IL-17A, IL-23, and lipopolysaccharide (LPS) in saliva, and to examine whether their salivary concentrations are associated with periodontal hea…

Recent shifts in global health policy have led to the implementation of mass drug administration (MDA) for neglected tropical diseases. Here we show how population genetic analyses can provide vital insights into the impact of such MDA on endemic parasite populations. We show that even a single round of MDA produced a…

INTRODUCTION: Influenza is a major cause of morbidity and mortality worldwide. Currently, licensed influenza vaccines are safe and effective. Any intervention aimed at reducing the burden of illness is worth analyzing from a clinical and economic perspective. OBJECTIVE: To assess the costs and benefits of an influenza…

BACKGROUND: Practice-based research links community-based physicians and their patients with investigators at academic institutions. In 1992, Western States Chiropractic College developed an infrastructure, the Center for Outcomes Studies, to support practice-based research. The Low Back Pain Study, undertaken in colla…

INTRODUCTION: End-stage renal disease patients are in rising trend globally, and they have been found to occur predominantly in developing countries. Many studies have been published before, within and across the countries, to know the clinicodemographic profile of end-stage renal disease patients. However, no such stu…

BACKGROUND: Although the benefits of using methodological frameworks are increasingly recognised, to date, there is no formal definition of what constitutes a 'methodological framework', nor is there any published guidance on how to develop one. For the purposes of this study we have defined a methodological framework…