42,360 papers found

OBJECTIVE: Although obesity is shown to be a risk factor for epithelial ovarian cancer, its role as a prognostic factor has been remained inconclusive. In this study, available evidences on this matter to date have been assembled for a meta-analysis to determine the effect of obesity on the survival of patients with ep…

This article reviews the current status of robotic-assisted radical prostatectomy (RARP) with outcome analysis. The published English literature (PubMed) database was searched extensively for major publications and large series on RARP. The search was carried out over the preceding 3-year period. Selected series were t…

OBJECTIVES: This study was designed to document the state of open access (OA) in the biomedical field in 2005. METHODS: PubMed was used to collect bibliographic data on target articles published in 2005. PubMed, Google Scholar, Google, and OAIster were then used to establish the availability of free full text online f…

OBJECTIVE: To conduct a comprehensive systematic review and high-quality meta-analysis to determine whether prophylactic drain placement reduces adverse bleeding events in thyroid surgery. DATA SOURCES: MEDLINE (OVID and PubMed), CENTRAL, CDSR, ACP Journal Club, DARE, EMBASE, PREMEDLINE, OLDMEDLINE, CINAHL, BIOSIS Pre…

BACKGROUND: This article provides a summary of the current status of the HIV/AIDS epidemic in Latin America, as well as an outline of the diverse responses to it. METHODS: A search of international databases (Pubmed and ISI-Web of Science), regional databases (Scielo and Lilacs), regional and national documents and UN…

OBJECTIVES: There is much controversy surrounding the diagnosis and treatment of patients with bipolar II disorder (BP II). To address the growing need to find effective treatment strategies for patients with BP II, this article identifies and summarizes available published evidence specific to the pharmacotherapy of B…

BACKGROUND: Uterine fibroids are a prevalent gynecologic condition traditionally associated with heavy menstrual bleeding and pelvic pressure. However, emerging evidence suggests that large uterine fibroids may also contribute to venous thromboembolism (VTE) by causing mechanical compression of pelvic veins and the inf…

OBJECTIVES: This article proposes a specific program of sequences of combinations of movements (SCM) based on motor development stages (MDS) to optimize the sports performance of elite professional athletes (EPAs). DESIGN: Narrative literature review. METHOD: Information on MDS, including biomechanical, physiological…

BACKGROUND: Hexavalent chromium (Cr (VI)) is a known neurotoxin and environmental contaminant. Despite its recognition, the underlying mechanisms by which Cr (VI) induces neurological damage remain insufficiently explored. The complexities of the Central Nervous System (CNS), including the Blood Brain Barrier (BBB) and…

INTRODUCTION: Oligodendrocyte progenitor cells (OPCs) are responsible for the generation of myelinating oligodendrocytes and are essential for myelination and repair of the central nervous system (CNS). In past decades, many methods have been presented for the reliable isolation and culture of OPCs to facilitate resear…

This systematic review analysed the analgesic efficacy of low-level laser therapy (LLLT) compared to conventional drug therapy and placebo for postoperative pain in endodontics. PubMed, PubMed Central, Scopus, LILACS, SciELO, Virtual Health Library, Embase and Open Gray were searched. Clinical trials assessing pain int…

Fibromyalgia (FM) and irritable bowel syndrome (IBS) often occur together. Patients with FM and IBS present similar symptoms, such as pain and fatigue; this leads to a delay in diagnosis and management. This systematic review explored the shared pathophysiology of these conditions in adults, focusing on the r…

PURPOSE: Problematic Internet Use (PIU) has been associated with emotional difficulties in childhood and adolescence. However, the directionality of this relationship remains unclear due to the lack of terminological consensus and wide variability in prevalence estimates. This systematic review aims to synthesize the l…

BACKGROUND & OBJECTIVE: The added value of lymphadenectomy is a widely debated topic, especially in cases of early-stage epithelial ovarian cancer (EOC). We present robust evidence through an updated systematic review and meta-analysis regarding the effects of lymphadenectomy on overall survival (OS) and progression-fr…

AIM: This systematic review aims to evaluate the clinical applications of infrared thermography (IRT) in rheumatic diseases (RDs), focusing on its potential as a non-invasive, cost-effective, and reliable tool for diagnosis, monitoring, and treatment to improve patient outcomes. METHODS: A systematic literature review…

BACKGROUND: Bioethics is fundamental in healthcare, guiding ethical decision-making and patient care. Translational bioethics (TB) aims to bridge the gap between ethical theories and real-world practice, including nursing. However, the concept of TB has not been clearly examined yet. Therefore, this concept analysis wa…

Benzodiazepines (BZDs) are widely used anxiolytics for treating various psychiatric conditions and for procedures requiring conscious sedation. Despite their therapeutic benefits, there is concern about their paradoxical effects, particularly the potential increase in suicidal ideation and suicide completion. This syst…

BACKGROUND: In the elderly, diagnosing and treating functional dyspepsia may be more challenging. The objectives of the study were to evaluate the prevalence and association of functional dyspepsia in adult individuals and elderly populations (especially ≥64 years) in the year 2024-2025 literature availab…

AIMS: The views of parents/caregivers about food programs in schools internationally is not well understood. This review aimed to synthesise what parents/caregivers identify as the key features of school food programs and their perspectives of these programs globally. METHODS: A mixed papers review was undertaken with…

BACKGROUND: The occupational hazards of glutaraldehyde are well known; the possibility of harm to the patients has been highlighted in the form of isolated reports only. OBJECTIVE: To synthesize evidence for contact mucosal injury or injury due to intraperitoneal instillation of glutaraldehyde following its use during…