2,589 papers found

BACKGROUND: The volume of digital data in health care is continually growing. In addition to its use in health care, the health data collected can also serve secondary purposes, such as research. In this context, clinical data warehouses (CDWs) provide the infrastructure and organization necessary to enhance the second…

BACKGROUND: Clinical trials are one of the most important sources of evidence for guiding evidence-based practice and the design of new trials. However, most of this information is available only in free text - e.g., in journal publications - which is labour intensive to process for systematic reviews, meta-analyses, a…

A variety of diseases, hereditary conditions, toxins and drugs may cause thrombocytopenia. Thrombocytopenia induced by ceftriaxone has been rarely reported. In this case, ceftriaxone-induced thrombocytopenia is presented in a 2-year-old girl due to rare presentation (Ref. 10). Full Text in free PDF www.bmj.sk.

BACKGROUND: Metastasectomy is performed on a select cohort of patients with advanced and/or recurrent bone and soft tissue sarcomas because of the potential for long term relapse free and overall survival associated with the procedure. However, the evidence supporting metastasectomy is difficult to summarize without a…

Broad absorption signatures from alkali metals, such as the sodium (Na I) and potassium (K I) resonance doublets, have long been predicted in the optical atmospheric spectra of cloud-free irradiated gas giant exoplanets. However, observations have revealed only the narrow cores of these features rather than the full pr…

Accurate organ segmentation is essential for clinical tasks such as radiotherapy planning and disease monitoring. Recent foundation models like MedSAM achieve strong results using point or bounding‑box prompts but still require manual interaction. We propose DescriptorMedSAM, a lightweight extension of MedSAM th…

The rapid growth of smartphone ownership and broadband access has created new opportunities to reach smokers with cessation information and support using digital technologies. These technologies can both complement and be integrated with traditional support modalities such as telephone quitlines and 1-on-1 clinical ces…

Fatty Acid Oxidation disorders represent an expanding group of inborn errors of metabolism. Clinical manifestations include episodic encephalopathy, hypoketotic hypoglycemia, Reye like episodes, hepatic, muscular, cardiac affection and sudden death. Analysis of urinary organic acids and plasma fatty acids of 44 clinica…

Online medical text is full of references to medical entities (MEs), which are valuable in many applications, including medical knowledge-based (KB) construction, decision support systems, and the treatment of diseases. However, the diverse and ambiguous nature of the surface forms gives rise to a great difficulty for…

We report two rare cases of patients presenting with unusual symptoms, which led to the diagnosis of a germ cell tumor. Metastatic germ cell tumor of testis involving the gastrointestinal tract and causing the occult gastrointestinal bleeding is described in the first case. The second patient is reported to have limbic…

Systematic reviews (SRs) contribute to implementing the 3Rs in preclinical research. With the ever-increasing amount of scientific literature, SRs require increasing time investment. Thus, using the most efficient review tools is essential. Most available software tools aid the screening process; tools for data extract…

The authors describe the incidence of postoperative complications after the surgical removal of third molars, most common postoperative complications and their symptoms as well as risk factors leading to greater incidence of postoperative complications (Ref. 17). Full Text (Free, PDF) www.bmj.sk.

The aim of our study is to show the clinical potential of laparoscopic treatment of pericardial effusions. In spite of the small number of the patients we want to bring to attention the benefit of this mininvasive procedure. The laparoscopic fenestration is indicated when the pericardial effusion persists after unsucce…

Haemophiliac pseudotumors are usually observed in the diaphysis of long bones. Pseudotumors due to psoas muscle hematoma are rare and surgical management is difficult. Surgical treatment of these lesions is usually associated with high morbidity and mortality rate. Here, we present a case with iliopsoas haemophiliac ps…

OBJECTIVE: The aim of this study was to determine differences between PBL as compared to modified PBL with special focus on acquiring EBM principles. METHODS: Two groups consisted of total 152 students (139 respectively). The use of EBM principles means integrating individual expertise with the best available external…

BACKGROUND: Schizophrenia is a leading cause of disability, and a shift from facility- to community-based care has been proposed to meet the resource challenges of mental healthcare in low- and middle-income countries. We hypothesized that the addition of mobile texting would improve schizophrenia care in a resource-po…

Invited for this month's cover is the Quantum Chemistry group (ALGC) of the Free University of Brussels (VUB) in collaboration with the Molecular Design and Synthesis (MolDesignS) group of the KU Leuven. The image shows how a variety of computational techniques, such as density functional theory, molecular dynamics, an…

Pulmonary artery dissection and aneurysms ruptures are rare events, occasionally reported as a cause of sudden death. We report a 27-year-old man who was admitted to the hospital with history of a loss of consciousness and died soon after resuscitation was performed. On autopsy macroscopic examination, 2500 ml partiall…

BACKGROUND: Conversational chatbots are an emerging digital intervention for smoking cessation. No studies have reported on the entire development process of a cessation chatbot. OBJECTIVE: We aim to report results of the user-centered design development process and randomized controlled trial for a novel and comprehe…

During the flight of birds, it is often possible to notice that some of the primaries and covert feathers on the upper side of the wing pop-up under critical flight conditions, such as the landing approach or when stalking their prey (see Fig. 1) . It is often conjectured that the feathers pop up plays an aerodyna…