Systematic review of the benefits and harms of calcitriol and alfacalcidol for fractures and falls.
O'Donnell Siobhan, Moher David, Thomas Kelli, +2 more·Journal of bone and mineral metabolism
Our objective was to conduct a systematic review on the benefits and harms of calcitriol and alfacalcidol in the reduction of fracture and fall risk. Randomized controlled trials (RCTs) comparing these agents to placebo or calcium and reporting fracture and fall incidence were retrieved from MEDLINE, Embase, and the Co…