11,356,020 papers found

Patrilineality plays a significant role in determining and confirming an individual's family membership based on their father's lineage. However, despite the importance of patrilineality in some societies, male infertility-which contributes significantly to infertility and accounts for half of all cases-has emerged as…

During the COVID-19 pandemic, hospitality employees face a tremendous amount of job stress due to the decline in revenue and close contact with people. This study has three aims: first, to analyse the status quo of organizational-climate job stress on employee wellness in the hospitality industry during COVID-19; secon…

The Landon et al and the Crowther et al papers are both prospective trials comparing planned vaginal birth after a previous cesarean section (VBAC) with elective cesarean section in women eligible for a trial of labor. With 33,000 women, the cohort studied by Landon et al in conjunction with the National Institute of C…

OBJECTIVE: Teleconsultation has become a vital component of modern healthcare delivery, within which clinical reasoning is a critical determinant of care quality, directly impacting patient outcomes. This qualitative study aimed to explore and validate the key components that constitute effective (accurate, timely and…

BACKGROUND: Science communication can provide people with more accurate information on pandemic health risks by translating complex scientific topics into language that helps people make more informed choices on how to protect themselves and others. During pandemics, experts in medicine, science, public health, and com…

MicroRNAs (miRNAs) are non-coding RNAs that play a major role in gene regulation in several diseases. MicroRNA-502-3p (MiR-502-3p) has been previously characterized in a variety of human diseases such as osteoporosis, diabetes, tuberculosis, cancers, and neurological disorders. Our studies recently explored the new rol…

This commentary offers a thoughtful discussion of the study by Wei et al. published in the journal on the role of Olfactomedin 4 (OLFM4) in incomplete intestinal metaplasia, a gastric precancerous condition. The original paper introduces OLFM4 as a novel biomarker with potential enhanced diagnostic efficacy compared to…

UNLABELLED: Obective: Although much has been studied regarding high-utilizing patients of medical services, no studies have been published regarding high-utilizing patients of integrated primary care behavioral health (PCBH) services. The primary purpose of the current study was to examine characteristics of high-utili…

OBJECTIVE: Contrary to the long-standing prerequisite of inducing selective (ie, bifidogenic) effects, recent findings suggest that prebiotic interventions lead to ecosystem-wide microbiota shifts. Yet, a comprehensive characterisation of this process is still lacking. Here, we apply 16S rDNA microbiota profiling and m…

On July 10, 1976, an explosion at a chemical plant in Seveso, Italy, released up to 30kg of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-the most potent dioxin congener. Twenty years later, the Seveso Women's Health Study (SWHS) initiated a follow-up assessment of a cohort of female Seveso residents. Researchers collecte…

OBJECTIVE: The diaphragm, an internal barrier contraceptive device, is a candidate for a female-controlled method for preventing human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs). This study's objective was to examine how women who use the diaphragm differ from women using the pill and…

The COVID-19 crisis rapidly introduced telemedicine as the predominate modality to deliver healthcare however this change has not received attention in primary care settings and the health-related impacts are unknown. The study's objective was to explore the effects of physician-led synchronous telemedicine compared to…

Various studies in the medical literature reported significant cardiovascular involvement in patients with coronavirus disease 2019 (COVID-19) pneumonia. Atrial fibrillation (AF) was identified as the most commonly observed arrhythmia complicating COVID-19 infection with an increased risk of short-term mortality. We us…

BACKGROUND: Professional misconduct undermines safe and quality care; however, little is known about its nature and influential factors. AIM: This study aimed to explain the factors influencing professional misconduct in nurses. RESEARCH DESIGN: This qualitative study was conducted using the conventional content anal…

The investigational compound BIA 10-2474, designed as a long-acting and reversible inhibitor of fatty acid amide hydrolase for the treatment of neuropathic pain, led to the death of one participant and hospitalization of five others due to intracranial hemorrhage in a Phase I clinical trial. Putative off-target activit…

BACKGROUND: Canada's drug toxicity crisis has burdened some populations disproportionately. This study identifies populations facing higher (or lower) rates of acute toxicity death (ATD) relative to a comparison group, using integrated Canadian Census Health and Environment Cohort data. METHODS: This national prospect…

This study assessed the effect of low-dose aspirin (81 mg) on thrombin generation in healthy volunteers using the calibrated automated thrombogram (CAT). This single-center prospective crossover study involved healthy volunteers, each serving as their own control. After Institutional Review Board approval and in…

OBJECTIVE: The development of evidence-based medicine has contributed to improved patient outcomes. This study aims to identify the trends in levels of evidence in otolaryngology journals over time, as represented by the 4 most widely circulated peer-reviewed otolaryngology journals. METHODS: A review of all articles…

PURPOSE: To assess the utility of virtual reality (VR) in stroke rehabilitation. METHOD: The Medline, Proquest, AMED, CINAHL, EMBASE and PsychInfo databases were electronically searched from inception/1980 to February 2005, using the keywords: Virtual reality, rehabilitation, stroke, physiotherapy/physical therapy and…

STUDY DESIGN: A literature review. OBJECTIVES: To determine the frequency of potential type II errors published in the spine surgical literature. SUMMARY OF BACKGROUND DATA: The randomized controlled trial is the strongest clinical evidence available in investigational medicine. Unfortunately, it is common for random…