98,323 papers found

BACKGROUND: Childhood injuries claim around a million lives around the world each year. A community-based study on childhood injuries would provide valuable information on the epidemiology of injuries. OBJECTIVE: To assess the prevalence of unintentional childhood injuries in an urban locality and determine various so…

Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most common fever syndrome in childhood. High disease activity (DA) dramatically impacts the health-related quality of life. Thus, effective and safe treatment is crucial. Colchicine might be effective, but data are still lacking. St…

INTRODUCTION: For phosphodiesterase type 5 (PDE5) inhibitors, such as sildenafil, the only approved indication in women is for pulmonary arterial hypertension. These drugs are increasingly being proposed and tested for treatment of female infertility and complications in pregnancy. However, the extent of use of PDE5 in…

We examined the presence of possible Recent refugia of Pleistocene mammalian faunas in Eurasia by analysing regional differences in the mammalian species composition, occurrence and extinction rates between Recent and Last Glacial faunas. Our analyses revealed that most of the widespread Last Glacial species have survi…

The activity of kidney transplantation at Policlinico University Hospital, now the Ca' Granda Foundation, was established by Professor Edmondo Malan, who performed the first deceased donor transplantation in Milan, Italy, in 1969. Since then, 2989 kidney transplant procedures (2760 first, 219 second, 10 third transplan…

The safety, tolerability, and pharmacokinetics of an oral solution of itraconazole and its active metabolite hydroxyitraconazole were investigated in an open multicenter study of 26 infants and children aged 6 months to 12 years with documented mucosal fungal infections or at risk for the development of invasive fungal…

BACKGROUND AND AIMS: The impact of disease progression in NAFLD on liver outcomes remains poorly understood. We aimed to investigate NAFLD progression using longitudinal liver stiffness measurements (LSM) by serial magnetic resonance elastography (MRE) and the association with liver outcomes. APPROACH AND RESULTS: All…

BACKGROUND: Due to the high transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), governments adopted preventive measures, such as social distancing and obligatory social immobilization, which negatively affected access to health services, in…

INTRODUCTION: In the last time, there is a negative dynamics of indicators of the health of the child population in Ukraine in connection with socio-economic problems. AIM: The analysis of the data of the incidence and the prevalence of diseases among the children of the Poltava region in comparison with those of Ukra…

Vibrio parahaemolyticus was discovered by Tsunesaburo Fujino after a shirasu food poisoning outbreak in 1950, but at that time the isolate was named Pasteurella parahaemolytica, not Vibrio. Although the isolate resembled Vibrio, some properties did not correspond with those of Vibrio. For example, the curved cell form…

The use of nanoparticles in stem cell research is relatively recent, although very significant in the last 5 years with the publication of about 400 papers. The recent advances in the preparation of some nanomaterials, growing awareness of material science and tissue engineering researchers regarding the potential of s…

Among the 831 students in the first and last-but-one year of medical studies, 21% were smokers, 4% occasional smokers, 63% non-smokers and 5% former smokers. There were no statistically significant difference in smoking habits between the first and fifth years of study. The different semesters did, however, reveal sign…

BACKGROUND: Up to 7.5% of tined-lead removals in patients having sacral neuromodulation (SNM) therapy are associated with a lead breakage. It is still unclear what adverse effects can be caused by unretrieved fragments. The aim of our study was to describe the lead removal technique we have been using for the last 2&#x…

The aim of our study was to evaluate the shoulder function after clavicular hook plate fixation of acute acromioclavicular dislocations (Rockwood type III) in a population group consisting exclusively of high-demand military personnel. This prospective study was carried out at a tertiary care military orthopaedic centr…

INTRODUCTION: The incidence of inflammatory bowel disease (IBD) varies widely according to geographical area and has been reported to have increased in the last few years. No data are available on the current incidence of this disease in Madrid (Spain). AIM: to determine the incidence of inflammatory bowel disease in…

BACKGROUND: In Catalonia, as in most Spanish regions, the conjugate pneumococcal vaccine is not publicly funded, except for immunocompromised or high-risk children. This study assessed current vaccine coverage in the region of Tarragona, analyzing trends in vaccine uptakes throughout the 2002-2011 period by analyzing u…

The last 2 years have marked a dramatic escalation in the level of abortion-related violence in both Canada and the US. Two physicians and two clinic workers have been murdered since 1993, and last November the violence may have moved north of the border with the shooting of Dr. Garson Romalis in Vancouver. Milan Korco…

During the last 20 years, 1,000 patients were operated on for a single cancer of the colon, 497 men and 503 women (mean age: 67 years). Resection was performed in 93% of the patients and resection with curative intent in 80% of the patients. Carcinomas located on the left colon were usually treated by segmental resecti…

In Europe, the Quaternary is characterized by climatic fluctuations known to have led to many cycles of contraction and expansion of species geographical ranges. In addition, during the Holocene, historical changes in human occupation such as colonization or abandonment of traditional land uses can also affect habitats…

PURPOSE: The objective was to evaluate the use of German health insurance claims data on medications over the last 10 years by a review of published studies. METHODS: PubMed and Scopus were searched for relevant studies published in 1998 through 2007. RESULTS: A total of 70 studies were included. Use of these data in…