5,006,974 papers found

BACKGROUND: Although several meta-analyses have examined the association between bipolar disorder (BD) and its comorbid health outcomes, this evidence has not been comprehensively assembled. OBJECTIVE: We aimed to systematically review existing meta-analyses based on multiple physical outcomes and validate the evidenc…

BACKGROUND: Although evidence on the association between per- and polyfluoroalkyl substances (PFASs) and human health outcomes has grown exponentially, specific health outcomes and their potential associations with PFASs have not been conclusively evaluated. METHODS: We conducted a comprehensive search through th…

BACKGROUND: Urgent and emergency care (UEC) settings provide an opportunity to prevent ill-health and promote healthy lifestyles with potential to screen and deliver interventions to under-served, at-risk populations. The aim of this study was to synthesise and summarise the evidence on the effectiveness and implementa…

Fruit and vegetables (F&V) have been a cornerstone of healthy dietary recommendations; the 2015-2020 U.S. Dietary Guidelines for Americans recommend that F&V constitute one-half of the plate at each meal. F&V include a diverse collection of plant foods that vary in their energy, nutrient, and dietary bioactive c…

Open abdomen therapy is an effective method for the treatment of severe intra-abdominal infections, abdominal hypertension and other critical abdominal diseases. Bases on systematic reviews of indications, classification and staging of wounds, principles and approaches of open abdomen therapy, abdominal closure measure…

Knapp, Stohl, and Reardon's (1981) seminal work reported that some messages may be "remembered for a long time and have a profound influence on a person's life" (p. 27). While the foundational concepts of this framework have offered a meaningful contribution to memorable messages research, this article seeks to unpack…

Breakthrough pain is a distinct pain state that is common in patients with cancer pain and which is associated with significant morbidity in this group of patients. The aim of this article is to highlight important journal articles relating to breakthrough pain that have been published within the last year, including a…

BACKGROUND: The problem of missing studies in meta-analysis has received much attention. Less attention has been paid to the more serious problem of double counting of evidence. METHODS: Various problems in overstating the precision of results from meta-analyses are described and illustrated with examples, including p…

Sepsis remains a common problem in all age groups. Recently surviving sepsis campaign has taken up a worldwide initiative by publishing international guidelines 2008 with a hope to disseminate information regarding management of sepsis for all age groups. This article presents a review of recent advances as they apply…

(1) Sialorrhoea is a common condition in patients with Parkinson's disease that has a negative impact on patient quality of life. (2) Traditionally, muscarinic antagonists have been the pharmacological agents of choice for the treatment of sialorrhoea; however, these agents are frequently associated with adverse events…

Metastatic dissemination of malignant glioma is rare. Metastatic disease usually occurs within the neuraxis but extracranial spread to the liver, spleen, lung, peritoneum and lymph nodes can also occur. In most cases of metastatic disease, the patient has previously undergone a craniotomy. The prognosis is uniformly po…

One type of "ready-to-wear" theories that can bring about better nursing care outcomes regardless of their philosophical bases is situation-specific theories proposed by Im and Meleis in 1999. In this paper, some propositions for an integrative approach to the development of situation-specific theories are made. First,…

Over the last 20 years, the development of meta-analysis has been aimed at obtaining objective synthesis of the available results on specific research questions. The main achievements of meta-analysis include the application of techniques to perform systematic literature searches and to obtain unbiased selection of stu…

Although breast-conserving therapy (BCT) is an accepted alternative for the treatment of breast cancer, numerous controversies surround the selection criteria and the treatment details. A review of the literature revealed that patient selection is of critical importance. However, there is disagreement over the relative…

STATEMENT OF PROBLEM: Systematic reviews (SRs) are time-consuming and resource-intensive processes. Whether large language models (LLMs) can improve the process is unclear. PURPOSE: The purpose of this study was to evaluate the accuracy and reliability of 4 LLMs (GPT-4, Gemini, Claude, and Elicit) in performing SR tas…

BACKGROUND: Despite its wide acceptance and recommendation as an essential tool for radiation exposure optimization and the increasing influx of high-technology imaging facilities, there is still a paucity of available data on the Diagnostic reference level (DRL) of ionizing radiation radiological examinations and its…

BACKGROUND: Cognitive capacity and function affect daily activities, independence, and overall well-being across the life course. OBJECTIVE: To map and synthesise evidence on interventions that measured cognitive capacity at any life stage across the life course from Cochrane and Campbell systematic reviews. DESIGN:…

This is a protocol for a Cochrane Review (overview). The objectives are as follows: To summarise the evidence on the effects of ocular light exposure interventions on sleep, circadian rhythms, rest-activity cycles, mood, and cognitive function in older adults. To outline opportunities and challenges for developing evid…

INTRODUCTION: An association between type 2 diabetes and osteoarthritis has been postulated. The present umbrella review of systematic reviews and meta-analyses investigated possible bidirectional relationships between type 2 diabetes and osteoarthritis. METHODS: PubMed, Scopus, Web of Science, and Cochrane Library da…