391,885 papers found

BACKGROUND: The shortage of donor hearts significantly limits heart transplantation. Innovative machine perfusion strategies have emerged to address the shortcomings of traditional static cold storage after brain death (SCS-DBD), potentially enhancing outcomes and broadening donor eligibility. We performed a systematic…

OBJECTIVES: Temporal trends in comparative meta-analyses of interventions are well-recognized in the medical literature. For studies of diagnostic test accuracy (DTA), evidence of temporal trends is growing and the importance of assessing and reporting them has been highlighted in recent guidelines on postmarket survei…

BACKGROUND: Multivariate meta-analysis (MVMA) jointly synthesizes effects for multiple correlated outcomes. The MVMA model is potentially more difficult and time-consuming to apply than univariate models, so if its use makes little difference to parameter estimates, it could be argued that it is redundant. METHODS: We…

The study compares the health impacts of various nonpharmacologic interventions on cognitive function, daily functioning, depression, and quality of life among people living with dementia.A comprehensive search was conducted across three databases-PubMed, Airiti Library, and Scopus-to identify eligible randomized contr…

We used meta-analytic statistical techniques to synthesize findings from studies that evaluated propranolol HCI for the prevention of recurrent migraine (2,403 treated patients). The modal migraine sufferer treated in these studies was a female, about 37 years of age, who suffered from common (rather than classical) mi…

Graphs are an essential part of scientific communication. Complex datasets, of which meta-analyses are textbook examples, benefit the most from visualization. Although a number of graph options for meta-analyses exist, the extent to which these are used was hitherto unclear. A systematic review on graph use in meta-ana…

We conducted a meta-analytic study to measure the risk of uterine cervical cancer in former and current smokers. A literature search from 1966 to 1988 identified 139 MEDLINE citations. Of these, five studies reported appropriate and complete data for meta-analysis. A recent study conducted by the authors was also inclu…

BACKGROUND: Degenerative spondylolisthesis (DS) is a common cause of low back pain and lumbar spinal stenosis, necessitating various surgical interventions. Traditional management includes fusion surgery, but recently decompression with or without dynamic stabilization has been explored. However, the relative efficacy…

Reviewed 87 studies of children's adjustment to physical disorders in a meta-analysis. Results indicate (a) children with such disorders show increased risk for overall adjustment problems, internalizing and externalizing symptoms; (b) risk was greatest in studies making comparisons to norms rather than to study contro…

Meta-analysis was used to cumulate the results from 633 studies of smoking cessation, involving 71,806 subjects, that reported the proportion of successful quits. Self-care methods do not appear to be as effective as formal intervention methods. Instructional programs involving physicians were not more effective than o…