42,378 papers found

The aim of this study was to evaluate the curative effects and safety of capecitabine plus oxaliplatin compared with 5-fluorouracil (5-FU) plus oxaliplatin in patients with metastatic colorectal cancer (MCRC). We searched the Cochrane Central register of Controlled Trials (CENTRAL), PubMed, Ovid, ScienceDirect, EBSCO,…

OBJECTIVE: To compare the anchorage effects of the implants and the headgear for patients with anterior teeth retraction in terms of incisor retraction, anchorage loss, inclination of maxillary incisors, positional change of maxillary basal bone, and treatment duration. MATERIALS AND METHODS: An electronic search for…

BACKGROUND: Tympanic membrane retractions are commonly managed by ENT surgeons. There is currently no consensus as to the indications, timing and options for management of this condition. OBJECTIVES: To study the effectiveness of different surgical options in the management of tympanic membrane retractions. SEARCH ST…

BACKGROUND: A meta-analysis on the survival of short implants compared to conventional implants has never been performed. Therefore, the aim of this study was to address the focused question "Is there a significant difference in survival between short (<or=8 or <10 mm) and conventional (>or=10 mm) rough-surface dental…

BACKGROUND: Pain is a common and clinically relevant symptom during chemotherapy for breast cancer, negatively affecting quality of life. Although physical exercise is recommended and considered safe during chemotherapy, it may acutely exacerbate pain while potentially reducing it in the long term. Therefore, this stud…

AIM: The purpose of this systematic review was to investigate the effects of rocker sole shoes on temporal-spatial parameters, kinematics, kinetics, plantar pressure, and electromyography (EMG) activity during walking. METHOD: A systematic search was conducted in the PubMed, Web of Science, Scopus, and Cochrane Centra…

INTRODUCTION/BACKGROUND: Neurosarcoidosis is an uncommon manifestation of systemic sarcoidosis, and isolated cranial nerve involvement is exceptionally rare; therefore, histological biopsy is essential to confirm diagnosis. Isolated trigeminal neurosarcoidosis (TNS), often radiologically mimics common tumors like schwa…

Proton pump inhibitors (PPIs) are widely prescribed in older adults, often beyond recommended durations, raising concerns about nutrient depletion. This systematic review examined the impact of long-term PPI use (&#x2265;6 months) on micronutrient status in older adults receiving polypharmacy. A comprehensive search of…

INTRODUCTION: Mobile phone text message reminders (MPTMRs) have been implemented globally to promote vaccination uptake and recall rates. This systematic review evaluated the effectiveness of MPTMRs on vaccination recall rates. METHODS: We included randomized controlled trials of caregivers of children, adolescents, o…

OBJECTIVE: To provide pooled evidence on the association between central sarcopenia and risk of mortality and/or complications among geriatric patients with moderate to severe trauma. METHODS: We conducted a systematic search in PubMed, EMBASE, and Scopus databases for relevant observational studies documenting the as…

OBJECTIVES: Cases of severe lower limb injuries that previously were amenable only to amputation can now, in certain circumstances, be managed with reconstruction. The present systematic review and meta-analysis was designed to compare the results of amputation and reconstruction in severe lower extremity injuries. ME…

OBJECTIVE: Lipid-laden macrophage index (LLMI) has been proposed as a marker for aspiration on bronchoalveolar lavage. It has also been studied as a marker for gastroesophageal reflux and other pulmonary diseases. This review aims to determine the clinical correlation between LLMI and pediatric aspiration. DATA SOURCE…

The most common cancer in women worldwide is cervical cancer. For early-stage disease the standard treatment is radical hysterectomy. One of the main issues faced by surgeons performing a radical hysterectomy is the wide variation in the terminology used to define the procedure and the nomenclature used to describe the…

INTRODUCTION: Despite the many unknowns about its exact mechanism, progesterone and progestins are being successfully used to prevent luteinizing hormone (LH) surge during ovarian stimulation for assisted reproductive technology (ART). We will review progestin primed ovarian stimulation (PPOS) protocols in comparison w…

Obesity is a complex and multifactorial disease that is strongly associated with multiple comorbidities and mortality. Weight reduction in overweight and obese patients was highly desired to minimize future complications. Meal replacement is emerging as one of the effective tools to promote weight loss. Isoflavones and…

Literature reported the effectiveness of internet-based interventions over face-to-face interaction on tobacco quitting; however, limited sample size reinforces to integrate and analyze these studies' findings to reach a single conclusion. Therefore, we evaluated the effectiveness of the internet as an intervention app…

BACKGROUND: The novel coronavirus (COVID-19) epidemic initially appeared in Wuhan, Hubei Province, China, on 31 December 2019 and was spread rapidly worldwide. Most underlying diseases reported with COVID-19 patients are diabetes, hypertension, coronary heart diseases, and cerebrovascular disease. We do not know whethe…

PURPOSE: Tracheal tube introducers and stylets remain some of the most widely used devices for aiding practitioners in performing endotracheal intubation (ETI). The purpose of this systematic review is to evaluate the efficacy of tracheal tube introducers and stylets for ETI in the prehospital setting. METHODS: A lite…

BACKGROUND: There is increasing evidence regarding the influence of the intestinal microbiota on the disease processes of various organs and systems. Dysbiosis, that is, alteration of the composition and function of the microbiota may constitute an important risk factor for the development of mental disorders, namely,…

BACKGROUND: So far, there was no consensus regarding balloon dilation time in endoscopic papillary balloon dilation (EPBD). Thus, we conducted a systematic review and meta-analysis to compare the stone removal and overall complication rates of dilation of short and long duration with EPBD. METHODS: The Cochrane Centra…