98,328 papers found

BACKGROUND: Our aim was to summarize and compare relevant recommendations from evidence-based CPGs (EB-CPGs). METHODS: Systematic review of clinical practice guidelines. DATA SOURCES: PubMed, EMBase, Cochrane Library, LILACS, Tripdatabase, and additional sources. In July 2017, we searched CPGs that were published in…

BACKGROUND: Epidemiological studies have reported high levels of periodontal diseases worldwide. Over the last 40 years, Norway has introduced several measures including major financial support to reduce periodontal diseases. The aims of this study were to establish the present level of periodontal treatment, the…

BACKGROUND: Prior studies have demonstrated improved disease-specific survival of mycosis fungoides (MF) patients over the last 50 years. OBJECTIVE: To analyse patterns of survival and incidence from 1973 to 2016 and determine whether apparent improvements in MF-specific survival are due to lead-time bias rather…

BACKGROUND: Leishmaniasis is one of the neglected infectious diseases of the world. This disease largely affects individuals of low socio-economic level, mainly in developing countries. METHODS: The aim of this study was to investigate the cumulative number of cases, case fatality rate, and trend in incidence and mort…

OBJECTIVES: To explore if the Barcelona Integral Care Program for Doctors with mental disorders (PAIMM, in Catalan) has achieved its goal of enhancing earlier and voluntary help-seeking amongst sick doctors. MATERIAL AND METHODS: We conducted a retrospective chart review of 1363 medical records of physicians admitted…

PURPOSE: To evaluate a low-cost technique for single-incision laparoscopic cholecystectomy (SILC) in children with biliary dyskinesia. PATIENTS AND METHODS: Eighteen children with biliary dyskinesia underwent SILC between March and September 2010. Two 5-mm trocars and a directly introduced grasper were inserted throug…

UNLABELLED: This study aims at (1) Assessing trends in maternal mortality in kuwait (2) Define strategies for prevention. METHODS: Retrospective analysis of maternal deaths that occurred among, 55,979 live births at a tertiary hospital, between 1980 and 2009. RESULTS: There were 14 maternal deaths, and 55,979 live bi…

Mantle cell lymphoma (MCL) is a rare non-Hodgkin lymphoma (NHL) entity. The translocation between chromosomes 11 and 14 is the cytogenetics hallmark of MCL. This translocation leads to the dysregulation of the CCDN1 gene, and overexpression of cyclin D1 which promotes cell cycling. Despite a classical phenotype (CD19+,…

By today, systemic therapy for pancreatic cancer remains a huge challenge considering the last 10 years existing data. In 1997, gemcitabine emerged as a new reference treatment in advanced disease stage displaying a valuable clinical benefit rate but an overall survival limited to 6 months. In 2007, around 20 large pha…

OBJECTIVE: To determine trends in urolith composition in cats. DESIGN: Retrospective case series. SAMPLE POPULATION: 5,230 uroliths. PROCEDURES: The laboratory database for the Gerald V. Ling Urinary Stone Analysis Laboratory was searched for all urolith submissions from cats from 1985 through 2004. Submission forms…

SETTING: Five years after the last survey of drug-resistant tuberculosis in Japan, a serious new phenomenon has gradually begun to appear. A nationwide survey was conducted by the Tuberculosis Research Committee. OBJECTIVE: To determine resistance patterns to five anti-tuberculosis drugs and risk factors. DESIGN: Cul…

OBJECTIVES: The aim of this retrospective case series was to report the performance up to 5 years of an innovative surgical design (the apically incised coronally advanced surgical technique [AICAST]) for the regenerative treatment of one- or two-walled intrabony periodontal lesions. METHOD AND MATERIALS: After comple…

Changes in lifestyle can be significantly reflected in growth and development. Adaptations to reduced levels of physical activity, together with non-corresponding nutritional intakes, can result in body build and body composition changes at an early age. The present cross-sectional study aimed to evaluate the secular t…

A systematic review of the research conducted on Teaching Games for Understanding in Physical Education in the last six years (2014-2019), updating and expanding with new categories the last published review by Harvey and Jarret in 2014. Four databases were used to select those articles that included information on the…

The ArrayExpress Archive of Functional Genomics Data (http://www.ebi.ac.uk/arrayexpress) is an international functional genomics database at the European Bioinformatics Institute (EMBL-EBI) recommended by most journals as a repository for data supporting peer-reviewed publications. It contains data from over 7000 publi…

BACKGROUND: In asthma, socio-economic and health care factors may operate by a number of mechanisms to influence asthma morbidity and mortality. AIM: To determine the quality of medical care including the patient perception of the doctor-patient relationship, and the level of socio-economic disadvantage in patients ad…

AIMS: To examine the prevalence of asthma symptoms in a random population sample of New Zealand adults aged 20-44 years drawn from the general and Maori electoral rolls as phase I of an international study of asthma prevalence. METHODS: Subjects aged 20-44 years in Auckland, Hawkes Bay, Wellington and Christchurch, we…

Percutaneous transluminal coronary angioplasty (PTCA) of patients with unstable angina pectoris is an established therapy, although the rate of major complications (death, myocardial infarction, emergency coronary artery bypass operation) is higher than in patients with stable angina. This study analyzes the results of…

Sci-athon is a collaborative event for graduate students and postdoctoral scholars designed to harness diverse scientific backgrounds toward solving global issues in chemistry. The last 2 years have yielded surprisingly different versions of this annual competition.

In the 10 years thathas been published the scientific changes have been amazing, as have the changes in the culture of science.