44,731 papers found

Methamphetamine (MA) abuse remains a global health challenge despite intense research interest in the development of pharmacological treatments. This review provides a summary of clinical trials and human studies on the pharmacotherapy of methamphetamine use disorder (MUD). Areas covered: We summarize published clinica…

The main focus of this narrative review is to present and discuss the most relevant clinical data about the pharmacological therapy for alcohol use disorders. By using PubMed we conducted a review of the clinical literature on drugs related to alcohol use disorders. All data are presented following the three phases of…

BACKGROUND: Non-cardiac chest pain is one of the most common functional gastrointestinal disorders. By recognising that gastro-oesophageal reflux disease (GERD), oesophageal dysmotility and oesophageal hypersensitivity are the main underlying mechanisms of NCCP, a more directed therapeutic approach has been developed.…

OBJECTIVE: To assess the effect of kidney-tonifying (KT) Chinese herbal formula for senile hypertension (SH). METHODS: A total of five databases (CENTRAL, Pubmed, CBM, CNKI, and VIP) were searched for published and unpublished randomized controlled trials (RCTs) up to November 30th, 2013. We included RCTs that confoun…

Phytol (3,7,11,15-tetramethylhexadec-2-en-1-ol), a diterpene member of long and ramified chain of unsaturated acyclic alcohols. The objective of study was to conduct a systematic review of this diterpene and its pharmaceutical applications in Nervous System diseases in humans and/or rodents. Periodicals bases, such as…

This systematic review described the criteria and main evaluations methods procedures used to classify neuropsychiatric systemic lupus erythematosus (NPSLE) patients. Also, within the evaluations methods, this review aimed to identify the main contributions of neuropsychological measurements in neuroimaging studies. A…

The current study evaluated the influence of stimulant drugs used for attention deficit and hyperactivity (ADH) on statural growth. The authors conducted a literature review collecting published articles on attention deficit hyperactivity disorder and its relationship with short stature. The source of information was t…

OBJECTIVE: To review the ways attention deficit disorder (ADD) presents in adults in primary care and to suggest treatment approaches. SOURCES OF INFORMATION: PsycINFO, PubMed, and Academic Search Elite databases were searched. Level I evidence supports the effectiveness of stimulants for treating ADD in adults, and m…

Multiple arteriovenous fistula aneurysm (AVF-An) repair is critical for maintaining access, but the optimal surgical approach (synchronous (one-stage) vs staged (two-stage)) remains uncertain. Our aim is to compare one-stage and two-stage surgical repair of multiple AVF-An regarding patency and complications. We conduc…

The evidence from the clinical studies on the influence of yoga and meditation on gut microbiota in humans has been summarized in this systematic review. Searches were conducted until November 2023 in four electronic databases: SCOPUS, PubMed, Google Scholar, and Cochrane Controlled Registry of Trials (CENTRAL) to find…

BACKGROUND AND AIMS: The popularity of herbal medicine continues to increase in modern health care practices; therefore, it is imperative to recognize and address potential risks associated with its everyday use. The Asteraceae family is one of the most extensively utilized medicinal plant families due to its abundance…

Recurrent urinary tract infections (rUTIs) present a significant clinical challenge, particularly due to the associated overuse of antibiotics and the rise in antimicrobial resistance. This systematic review evaluates the current literature on the use of intravesical therapies as an alternative treatment for rUTIs. Two…

OBJECTIVE: To review the literature on the neuropharmacology of synthetic cathinones. METHODS: A comprehensive literature search was carried out across multiple databases (mainly PubMed, World Wide Web, and Google Scholar) using relevant keywords. RESULTS: Cathinones exhibit a broad toxicological profile, mimicking t…

While the rapid growth of mobile mental health applications has offered an avenue of support unbridled by physical distance, time, and cost, the digitalization of traditional interventions has also triggered doubts surrounding their effectiveness and safety. Given the need for a more comprehensive and up-to-date unders…

The objective of this systematic review is to examine metabolic dysfunction, specifically metabolic syndrome and its components, as well as type 2 diabetes mellitus (T2DM) as it relates to individuals with a diagnosis of Autism Spectrum Disorder (ASD). We searched PubMed, Embase, Cochrane, PsychInfo, and Scopus from Ja…

is an economical and medicinal plant of wide indigenous uses including hypertension, diarrhea, respiratory ailments, stomach troubles, infertility problems, cancer, and snakebite. Despite these attributes,is largely underutilized, notwithstanding the few progresses made to date. Here, we reviewed the available findings…

PURPOSE OF REVIEW: The number of applications for peripheral nerve stimulation (PNS) in the pain management field is ever-growing. With the increasing number of clinical applications for peripheral nerve stimulation, the purpose of this article is to review the mechanism of action surrounding PNS, the recent literature…

BACKGROUND: The purpose of this literature review is to understand geographical information systems (GIS) and how they can be applied to public health informatics, medical informatics, and epidemiology. METHOD: Relevant papers that reflected the use of geographical information systems (GIS) in health research were ide…

PURPOSE: Review and discuss medications efficacious for seizure control, despite primary indications for other diseases, as treatment options in patients who have failed therapy with traditional antiepileptic drugs (AEDs). METHODS: Literature searches were conducted utilizing PubMed and MEDLINE databases employing com…

While there is no cure for autism spectrum disorder, psychopharmacologic agents are often used with behavioral and educational approaches to treat its comorbid symptoms of hyperactivity, irritability, and aggression. Studies suggest that at least 50% of persons with autism spectrum disorder receive psychotropic medicat…