97,488 papers found

BACKGROUND: Asbestos-related malignant pleural mesothelioma is one of the most lethal tumor types. The advent of antimetabolite treatment as pemetrexed, introduced in the early 2000s, may have increased survival on a population basis. In this study, we have analyzed population-based incidence and survival data over the…

BACKGROUND: Over the last two decades, the epidemiology, treatment strategy and mortality rate for congenital diaphragmatic hernia have changed. OBJECTIVES: To retrospectively analyze our experience with CDH of the last 22 years. METHODS: We reviewed the charts of all infants suffering from CDH between 1985 and 2007.…

BACKGROUND: A software based tool has been developed (Optem) to allow automatize the recommendations of the Canadian Multiple Sclerosis Working Group for optimizing MS treatment in order to avoid subjective interpretation. METHODS: Treatment Optimization Recommendations (TORs) were applied to our database of patients…

BACKGROUND AND OBJECTIVES: During the past few decades, females had been making conscious decision to have antenatal checkup from skilled health care provider due to improved education which had played a vital role to enhance their awareness regarding the importance of this comprehensive health service. The objective w…

On 19 March 2020, California put in place Stay-At-Home orders to reduce the spread of SARS-CoV-2. As a result, decreases up to 50% in traffic occurred across the South Coast Air Basin (SoCAB). We report that, compared to the 19 March to 30 June period of the last 5 years, the 2020 concentrations of PMand NOshowe…

Among about 400 patients with active arthritis and/or enthesitis who were referred to our department within the last two years, 140 of them were strongly suspected as having psoriatic arthritis by a comprehensive diagnostic procedure and after consulting specialists from dermatology, orthopedics, and radiodiagnostics a…

BACKGROUND: Treatment of cavernomas remains a challenge in surgically inaccessible regions. The purpose of this study was to evaluate outcomes after gamma-knife surgery (GKS) for these patients. MATERIALS AND METHODS: A retrospective review of 100 patients treated between 2003 and 2011 was conducted in order to evalua…

The importance of exercise in the elderly is widely recognized, but data on performances and drop-out in short running contests are lacking. This hinders stimulation and coaching of elderly persons in active aging. The aim of the study was to determine age-related changes in running performance in the most popular Dutc…

CONTEXT: The number of authors per article has increased markedly in recent years. Little is known about the hierarchical order of authorship and its change over time. OBJECTIVE: To assess the change in number and profile of authors of original articles published over a 20-year period in BMJ. It was hypothesized that…

OBJECTIVES: Determine frequency of remissions, relapses, and pharmacoresistance over two decades. Develop a composite measure of seizure control over that time. METHODS: Community-based cohort of children with newly diagnosed epilepsy prospectively followed for up to 21 years with frequent calls and periodic medical r…

BACKGROUND: Hip fracture patients have, in several studies, been shown to have excessive mortality. There is, however, a lack of mortality data, in comparison to incidence data, from the last decade in particular. OBJECTIVE: To study short- and long-term mortality in a population-based cohort of hip fracture patients…

OBJECTIVES: Hepatitis C virus (HCV) infection continues to be a major public health concern in China. There is little information available in the literature about age- and sex-specific HCV incidence trends. The goal of this study was to examine recent trends in HCV incidence rates in Hunan, China, according to age and…

BACKGROUND: Failure after total knee arthroplasty (TKA) may be related to emerging technologies, surgical techniques, and changing patient demographics. Over the past decade, TKA use in Korea has increased substantially, and demographic trends have diverged from those of Western countries, but failure mechanisms in Kor…

OBJECTIVE: By surveying a multiple sclerosis (MS) population, we tested the hypothesis that influenza vaccine uptake would not meet public health targets and that vaccine misconceptions would contribute to lower than desired uptake. METHODS: In spring 2020, we surveyed participants in the North American Research Commi…

BACKGROUND: Our aim was to summarize and compare relevant recommendations from evidence-based CPGs (EB-CPGs). METHODS: Systematic review of clinical practice guidelines. DATA SOURCES: PubMed, EMBase, Cochrane Library, LILACS, Tripdatabase, and additional sources. In July 2017, we searched CPGs that were published in…

BACKGROUND: Prior studies have demonstrated improved disease-specific survival of mycosis fungoides (MF) patients over the last 50 years. OBJECTIVE: To analyse patterns of survival and incidence from 1973 to 2016 and determine whether apparent improvements in MF-specific survival are due to lead-time bias rather…

BACKGROUND: Leishmaniasis is one of the neglected infectious diseases of the world. This disease largely affects individuals of low socio-economic level, mainly in developing countries. METHODS: The aim of this study was to investigate the cumulative number of cases, case fatality rate, and trend in incidence and mort…

OBJECTIVES: To explore if the Barcelona Integral Care Program for Doctors with mental disorders (PAIMM, in Catalan) has achieved its goal of enhancing earlier and voluntary help-seeking amongst sick doctors. MATERIAL AND METHODS: We conducted a retrospective chart review of 1363 medical records of physicians admitted…

BACKGROUND: Many western European carnivore populations became almost or completely eradicated during the last ~200 years, but are now recovering. Extirpation of wolves started in Finland in the 19th century, and for more than 150 years the population size of wolves has remained small. To investigate historic…

PURPOSE: To evaluate a low-cost technique for single-incision laparoscopic cholecystectomy (SILC) in children with biliary dyskinesia. PATIENTS AND METHODS: Eighteen children with biliary dyskinesia underwent SILC between March and September 2010. Two 5-mm trocars and a directly introduced grasper were inserted throug…