42,421 papers found

BACKGROUND: The effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in menopausal and postmenopausal women are not well characterized and may differ from other patient populations, given their different hormone profiles. Current research evaluating the effects of GLP-1RAs on weight loss, cardiovascular mark…

OBJECTIVES: Melioidosis is increasingly recognized in India, but available evidence remains fragmented across small reports. We aimed to synthesize national case-based data to describe the clinical spectrum and identify factors associated with mortality. METHODS: We systematically searched PubMed, Embase, and Web of S…

OBJECTIVE: This review presents an integrative framework of the "Mastication-Respiration Axis," proposing that the masticatory and respiratory systems interact to form a functional axis essential for the development and maintenance of cognitive health in brain circuits. DESIGN: We narratively synthesized studies ident…

We reviewed usage of nanomaterials and nanotechnology in otolaryngology. The literature search in this narrative review used Google, Google Scholar, PubMed, EBSCO, Proquest Central, Proquest Central, Web of Science and Scopus at Kırıkkale University. We searched for "Nanomaterials," "nanotechnology," "otola…

INTRODUCTION: Obstructive sleep apnea (OSA) is a common and serious breathing disorder. Several pathophysiological factors predispose individuals to OSA. These factors are quantifiable, and modifiable pharmacologically. AREAS COVERED: Four key pharmacotherapeutic targets are identified and mapped to the major determin…

BACKGROUND: One of the rare neuroinflammatory disorders is Neuromyelitis optica spectrum disorder (NMOSD) which involves the central nervous system (CNS), and develops by various etiologies. There is evident that viral infections could cause neurological disorders. In this regard, novel coronavirus (COVID-19) triggers…

Several studies in both multiple sclerosis (MS) and experimental autoimmune encephalitis (EAE) have shed light on the vascular mechanisms contributing to MS pathogenesis. The dysregulation of the hemostatic pathways revealed to play a pivotal role. Here, we review the numerous findings providing evidence on the involve…

PURPOSE: To compare the clinical results of standard corneal cross-linking (SCXL) with transepithelial corneal cross-linking (TECXL) in progressive keratoconus using a meta-analysis. METHODS: PubMed, EMBASE, and Cochrane Central Register of Controlled Trials were searched up to June 2020 to identify relevant studies.…

INTRODUCTION: Pregnant women are heavy users of Internet and this has an impact on their medical follow-up. The purpose of this study is to highlight the ethical issues related to the use of the Internet by women in their medical care.Methode: Through a systematic literature review conducted on PubMed/Medline, Web of S…

The favourable safety profile and ubiquitous nature of melatonin has led to an increase in its use in various clinical settings in adults and children. We performed a systematic review of published studies on the use of melatonin for anaesthetic indications in paediatric patients. To identify relevant articles, PubMed,…

. Pediatric traumatic brain injury (TBI) is associated with physical and psychobehavioral impairment in children. Effective rehabilitation programs postinjury are critical for children with TBI. Virtual reality (VR) has been increasingly adopted for brain injury rehabilitation. However, scientific synthesis is lacking…

OBJECTIVE: To identify the major risk factors for primary open-angle glaucoma (POAG) in individuals of African descent. METHODS: We searched PubMed for relevant articles, with results spanning April 1947 to present. All abstracts were reviewed and, where relevant to POAG and race, articles were catalogued and analyzed…

In recent years, Internet-delivered treatments have been largely used for pain monitoring, offering healthcare professionals and patients the ability to interact anywhere and at any time. Electronic diaries have been increasingly adopted as the preferred methodology to collect data related to pain intensity and symptom…

MOTIVATION: Anatomical entities ranging from subcellular structures to organ systems are central to biomedical science, and mentions of these entities are essential to understanding the scientific literature. Despite extensive efforts to automatically analyze various aspects of biomedical text, there have been only few…

STUDY DESIGN: Literature review. OBJECTIVE: To study the progress that has been made in neural plasticity for the past few decades. SETTING: United Kingdom/China. METHODS: An electronic search of relevant publications through PubMed was conducted using two key words: 'axonal regeneration' and 'neural plasticity'. Th…

BACKGROUND: Multiple line of clinical and experimental evidence demonstrates that both acute, moderate, and chronic, excessive alcohol use result in various abnormalities in the functions of the immune system. METHODS: Medline and PubMed databases were used to identify published reports with particular interest in the…

BACKGROUND: We evaluate the evidence that depression, anger, hostility, and anxiety are related to risk for the metabolic syndrome, focusing as well on its components of central adiposity and insulin resistance. In addition, we identify possible moderators of these associations and summarize plausible underlying biobeh…

Research on central nervous system tumors (CNSTs) has a significant impact on the diagnosis and prognosis of patients. Currently, CNSTs are classified according to the schema proposed by the World Health Organization (WHO), which considers clinical, histopathological, and molecular characteristics, highlighting the imp…

OBJECTIVE: To compare the differences in recurrence rates and surgical complications between thyroidectomy alone and thyroidectomy combined with central neck dissection as initial treatments to differentiated thyroid cancer and evaluate the clinic significance of central neck dissection for these patients. METHODS: Th…

BACKGROUND: Methylphenidate is a central nervous system stimulant commonly used in the treatment of attention deficit hyperactivity disorder (ADHD). While it is known to improve sustained attention, its effects on individuals without clinical conditions remain controversial. This integrative review investigates the imp…