42,421 papers found

OBJECTIVE: Epilepsy originating from the central lobule (i.e., the primary sensorimotor cortex) is a challenging entity to treat given its involvement of eloquent cortex. The objective of this study was to review available evidence on treatment options for central lobule epilepsy. METHODS: A comprehensive literature s…

OBJECTIVE: To assess patient and medication factors that contribute to metronidazole toxicity. DATA SOURCES: We searched PUBMED from 1965 through April 7, 2011, and performed a hand search of bibliographies. STUDY SELECTION: Case reports or case series reporting metronidazole-induced central nervous toxicity. DATA E…

BACKGROUND: The incidence and risk factors of peripherally inserted central catheter-related thrombosis in patients with breast cancer have not been fully elucidated. METHOD: Meta-analysis was performed by searching all studies on the incidence of peripherally inserted central catheter-associated thrombosis and risk f…

PURPOSE: To evaluate whether the application of carbon nanoparticles (CNs) in total or near-total thyroidectomy combined with central lymph node dissection (CLND) for thyroid cancer (TC) is beneficial to lymph node dissection, parathyroid, and recurrent laryngeal nerve (RLN) protection. METHODS: Relevant literatures w…

BACKGROUND: The aim of this study was to evaluate central corneal sensitivity after small incision lenticule extraction (SMILE) versus femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) for myopia. METHODS: Eligible studies were identified by systematically searching PubMed, the Cochrane Library, Embas…

BACKGROUND: Chronic pelvic pain (CPP) is a complex pain syndrome. Since its pathogenesis is still poorly understood and structural alterations in pain related brain regions may be present, there is a greater acceptance that sensitization of the central nervous system (CNS) plays an important role in the development and…

BACKGROUND: Thyroid carcinoma is the most common malignancy of the endocrine system. Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer, accounting for 70-90% of well-differentiated thyroid malignancies. Thyroid papillary microcarcinoma is a subtype of papillary carcinoma that included tumors w…

INTRODUCTION: Top-down central sensitization (TDCS), a condition in which the central nervous system amplifies and prolongs responses to peripheral stimuli, is associated with reduced quality of life, decreased work participation, increased healthcare utilization, and rising healthcare costs. This systematic review exa…

PURPOSE: Vertebral compression fractures (VCFs) are common among the elderly, causing significant morbidity, pain, and disability. This study quantitatively analyzes the vertebral height restoration via Kyphoplasty (KP) and Vertebroplasty (VP), along with the cement volume used and leakage percentage. Our meta-analysis…

INTRODUCTION: Cavernomas are vascular lesions with a genetic heritage that can be spotted on the central nervous system. Whenever these lesions are localized in eloquent regions, surgical resection is not recommended. In this type of situation, Gamma Knife stereotactic radiosurgery (GKSRS) could be a feasible option fo…

BACKGROUND: Swallowing is one of the most important activities in our life and serves the dual roles of nutritional intake and eating enjoyment. OBJECTIVE: The study aimed to conduct a meta-analysis to investigate the brain activity of swallowing. METHODS: Studies of swallowing using functional magnetic resonance ima…

BACKGROUND: To evaluate the best non-pharmacological interventions on apathy in patients with central nervous system (CNS) organic diseases. METHODS: We searched PubMed, Web of Science, Embase, Cochrane Library electronic databases, China national knowledge infrastructure, Wanfang and Chinese biomedical literature dat…

INTRODUCTION: Cancers of the central nervous system (CNS) include primary and metastatic tumors of varying cells of origin. These tumors may be benign or malignant, with incidence rates varying based on age, gender, and tumor type. While heterogeneous, all CNS tumors harbor risk of neurocognitive impairment, impairing…

INTRODUCTION: Stimulant medications, such as methylphenidate and amphetamine derivatives, and non-stimulant medications, such as atomoxetine, guanfacine, clonidine, and viloxazine, are considered the cornerstones of pharmacological treatment for attention-deficit/hyperactivity disorder (ADHD). However, a significant nu…

OBJECTIVE: Catheter-related bloodstream infections (CRBSI) or central line-associated bloodstream infections (CLABSI) occur frequently with long-term indwelling catheters. EDTA (Ethylenediaminetetraacetic acid) and other catheter lock solutions can prevent CRBSI/CLABSI. This study aimed to identify the role of EDTA loc…

STUDY OBJECTIVES: Primary mitochondrial diseases are caused by heritable or spontaneous mutations in nuclear DNA or mitochondrial DNA. Such pathological mutations are relatively common in humans and may lead to neurological and neuromuscular complication that could compromise normal sleep behavior. To gain insight into…

Post-transplantation lymphoproliferative disorders (PTLD) localized to the central nervous system (CNS) is a rare but potentially fatal side-effect of immunosuppression for organ transplantation. Till now, to the best of our knowledge, the total number of such cases reported worldwide is less than 100. In this survey,…

Streptococcus pneumoniae causes considerable global paediatric morbidity and mortality, despite the availability of safe and effective pneumococcal conjugate vaccines (PCVs). To justify the introduction of PCVs, accurate information on the burden of disease is required. Here, we present an appraisal of the pneumococcal…

To investigate the research trend and scope of prevention of central venous catheter-related bloodstream infection (CRBSI) in burn patients.The scoping review method was adopted. Pre-retrieval was carried out with search terms of ", , " and "central venous catheter, infection, catheter-related bloodstream infection, bu…

BACKGROUND: The cause of neck pain after whiplash is regarded as unknown, but Bioengineers have published studies implicating subfailure injuries of the cervical zygapophysial joints as a leading cause of pain. OBJECTIVES: A scoping review was undertaken to determine the size and nature of the evidence for subfailure…