42,426 papers found

BACKGROUND: The 2021 World Health Organization classification for brain tumors introduced several new entities and categories.Tumors of uncertain differentiation are a new subcategory that includes the intracranial mesenchymal tumor, FET-CREB fusion-positive; the CIC-rearranged sarcoma; and the Primary intracranial sar…

The study aimed to review the findings concerning the effects of exercises on Cobb angle and pain in patients suffering from cervical pain caused by thoracic kyphosis. Two investigators separately conducted a systematic review of the electronic literature from 2018 till 2022. PubMed, MEDLINE, Web of Science, Science Di…

Prucalopride is a third-generation, highly selective 5-hydroxytryptamine 4 (5-HT4) receptor agonist. Many recent studies indicate prucalopride may play an important role in various motility disorders. The aim of this study was to investigate safety and patient selection considerations when using prucalopride as gastrop…

Urbanization is an ongoing global process that is influencing and shaping individual mental health and well-being. This paper aims to provide an overview of the current literature containing state-of-the-art neuroscientific and mobile technologies that have been used to investigate the mental health implications of urb…

BACKGROUND AND AIM: The autonomic system is made of two divisions called the sympathetic and parasympathetic nervous systems and extends from the central to the peripheral nervous system for controlling homeostasis. Autonomic dysfunction, also known as dysautonomia, occurs when the nerves that control involuntary bodil…

OBJECTIVE: Treatment of a persistently painful snapping triceps and possibly snapping ulnar nerve. INDICATION: Snapping triceps. CONTRAINDICATIONS: General surgical risks. SURGICAL TECHNIQUE: Following the anterior transposition of the ulnar nerve (subcutaneously or submuscular), the snapping portion of the tri…

OBJECTIVE: Dental anxiety, fear and phobia have different etiology, response patterns, time courses, and intensities that justify a clear distinction between these constructs. Differentiation of dental anxiety, fear or phobia in practice is a critical prerequisite for developing and implementing effective treatment for…

INTRODUCTION: We reviewed literature pertaining to the current state of urological education for residents in the United States. METHODS: A literature review was performed to identify relevant manuscripts using a key word search of the PubMed® and MEDLINE® databases. Central themes of the literature were ide…

Obesity is associated with multiple comorbidities and psychosocial burdens, but often sexual dysfunction (SD) is overlooked. Bariatric surgery is the most effective treatment for morbid obesity, and its role in reversing SD is reviewed. A literature search of MEDLINE, PubMed Central, and Cochrane databases was conducte…

Uterine fibroids (UF) are common, benign gynecologic tumors, affecting one in three to four women, with estimates of up to 80%, depending on the population studied. Their etiology is not well established, but it is under the influence of several risk factors, such as early menarche, nulliparity and family history. More…

Ulcerative colitis (UC) is one of the main types of inflammatory bowel disease, which is caused by dysregulated immune responses in genetically predisposed individuals. Several genetic factors, including interleukin and interleukin receptor gene polymorphisms and other inflammation-related genes play central role in me…

Peripartum cardiomyopathy (PPCM) is a rare form of unexplained cardiac failure of unknown origin, unique to the pregnant woman with highly variable outcome associated with high morbidity and mortality. PPCM is fraught with controversies in its definition, epidemiology, pathophysiology, diagnosis and management. PPCM is…

Malignancy is considered as a pathological imbalance of tissue-cell societies, a state that emerges from tumor-host microenvironment in which host participates in induction, selection and expansion of the neoplastic cells. Invasion of these malignancies can be viewed as a derangement in the proper sorting of cell popul…

INTRODUCTION: The aim of this systematic review was to examine the effects of a lingual arch on mandibular arch dimensions when it is used as a space maintainer. METHODS: PubMed, Medline, Lilacs, Cochrane Central, and Cochrane Database of Systematic Reviews were surveyed for articles published between January 1980 and…

OBJECTIVE: To conduct a systematic review to assess and analyze the scientific evidence about the available therapies for bruxism in children. METHOD AND MATERIALS: The literature was searched using Medline, PubMed, Ovid, Biomed Central, EBSCOhost, ISI, Cochrane Library, Embase, LILACS, Scielo, Scirus, the Internet at…

BACKGROUND: In the critically ill, ischemia secondary to decreased renal blood flow (RBF) is believed to be central to the pathogenesis of acute renal failure (ARF); however, the scientific basis for this conclusion has not been systematically evaluated. METHODS: Systematic interrogation of the Pubmed database, and sc…

Thromboses in patients with hereditary bleeding disorders are uncommon. However, in some cases, the co-existence of prothrombotic risk factors may increase the likelihood of developing thrombotic complications in such patients. This review summarizes the cases of thrombosis reported in the literature and analyzes the m…

Research ethics committees occupy a central position in scientific governance, yet the literature reveals a persistent gap in structured, theoretically grounded guidelines for drafting ethical opinions. Opinions are frequently characterised by insufficient substantiation and communicative opacity, eroding researcher tr…

BACKGROUND: Microcirculation disorder is the main reason for the occurrence and development of kidney diseases. Studies have shown that endothelial cells play an important role in renal microcirculation disorders. To clarify the specific function of endothelial cells on renal microcirculation and its effect after damag…

This article outlines the history and development of Genes and Environment, the official journal of the Japanese Environmental Mutagen and Genome Society (JEMS). In the 1970s, there was growing concern about the mutagenicity of chemical substances, leading to the establishment of JEMS. The society began publishing its…