98,288 papers found

AIMS: People living with heart disease are at elevated risk of hospitalization during the last years of their life. The aim of this study was to describe hospitalization-related usage patterns, and associated cost burden, for patients living with heart disease in the last 6 years of their life. METHODS AND RESULTS: Th…

This meta-analysis aims to investigate the worldwide prevalence of primary angle-closure glaucoma (PACG) and its risk factors in the last 20 years.We conducted a systematic review and meta-analysis of 37 population-based studies and 144,354 subjects. PubMed, Embase, and Web of Science databases were searched for cross-…

During the last ten years, neurotoxicology has entered the mainstream of environmental toxicology as evidenced by numerous national and international conferences, formation of societies related to neurotoxicology, establishment and support of journals devoted to neurotoxicology and reliance of regulatory agencies on ne…

BACKGROUND: The importance of gender diversity is well recognized. Despite promising change in addressing gender disparity, there remains a significant gap in women's representation in urology. Worldwide, a lack of diversity has been observed at scientific meetings. This study analyses the trend in women's representati…

BACKGROUND: There is an increasing need for end-of-life care due to society's progressive aging. This study aimed to describe how hospitalizations evolve long-term and in the last months life of a cohort of deceased patients. METHODS: The study population were those who died in one year who lived in a district in sout…

Thirty-six female sheep, previously vaccinated against Bluetongue virus serotype 8 (BTV-8) using inactivated vaccines, were included in this field study. In Germany, vaccination was compulsory in 2008 and 2009, voluntary in 2010 and early 2011, and later, was prohibited in 2011. Due to their age, eighteen sheep had bee…

Elderly abuse is still a hidden problem, often underestimated. It is much more common than the data available suggest. Unfortunately, the incidence is expected to grow with the progressive increase in the elderly population in the future. The aim was to examine the available literature in the last 5 years to define the…

BACKGROUND: Although preventive health practices are extremely effective in preventing diseases and mortality, there is still a need to determine the frequency of these practices in different countries and improve these rates. The aim of this study was to evaluate preventive health practices in Turkey. METHODS: The st…

BACKGROUND AND OBJECTIVES: To compare long-term seizure control in patients with long-term VNS (vagal nerve stimulator) stimulation (VNS-on) with those who discontinued VNS after >3 years (VNS-off). METHODS: Patients with refractory epilepsy with VNS therapy for >3 years (and follow-up for >2 years after VNS discontin…

INTRODUCTION: Persistent B cell depletion is a rare complication of rituximab treatment, and its clinical implications are unknown. METHODS: This retrospective case series included patients with glomerular and autoimmune diseases who developed persistent B cell depletion (< 5 CD19CD20cells/&#x3bc;l persisting for > 2…

OBJECTIVE: To evaluate possible changes in the social, cultural and economical profile of our HIV infected patients appearing during the last five years and their potential impact on incidence, prevention, and follow-up of HIV infection. METHODS: We conduce a retrospective analysis of demographic, sociocultural, clini…

BACKGROUND/OBJECTIVE: The objective of the study was to provide current estimates of the prevalence and trends of overweight and obesity (OW+OB) in Mexican children and adolescents. SUBJECTS/METHODS: Body mass index objectively measured was analyzed for 37&#x2009;147 children and adolescents aged 0-19 years obtained i…

IMPORTANCE: Measuring health care utilization and costs before death has the potential to initiate health care improvement. OBJECTIVE: To examine population-level trends in health care utilization and expenditures in the 2 years before death in Canada's single-payer health system. DESIGN, SETTING, AND PARTICIPANTS: T…

We performed a retrospective, multicenter, open-label study to evaluate the efficacy of vagus nerve stimulation (VNS) in all patients in the Czech Republic who have received this treatment for at least 5 years (n=90). The mean last follow-up was 6.6+/-1.1 years (79+/-13 months). The median number of seizures among all…

This study was carried out to observe the trend in hormone receptors over the last 8 years in a tertiary cancer center in India. A total of 11,780 tumors analyzed for hormone receptors over the last 7 years were compared with the results of hormone receptor expression in a prior published study on 798 cases of breast c…

OBJECTIVE: The International League Against Epilepsy (ILAE) has proposed to expand the definition of remission to 10 years seizure-free with the last 5&#xa0;years off antiepileptic drugs (AEDs). We examined if a 10-year remission is needed to predict the lowest recurrence risk. METHODS: The population-based study coho…

INTRODUCTION: Osteonecrosis of the femoral head (ONFH) is a progressive and disabling disease with severe socioeconomic burdens. In the last 30 years, a growing number of publications have reported significant advances in understanding ONFH. However, only a few studies have clarified its global trends and current statu…

OBJECTIVE: To estimate effectiveness of tickborne encephalitis (TBE) vaccination by time interval (<5, 5-10 and 10+years) postvaccination. DESIGN: A retrospective, matched case-control study PARTICIPANTS: Cases-all adult (age 18-79) TBE cases in Switzerland reported via the national mandatory disease reporting surveil…

I have performed total knee arthroplasty (TKA) using patient- specific instrumentation (PSI) (TRUMATCH&#xae; Personalized Solutions, DePuy Synthes Joint Reconstruction, Warsaw, Indiana) since July 2009. Since that time, I have performed over 600 of these procedures, all at the same hospital and all using the same perso…

PURPOSE/BACKGROUND: The favorable effect of clozapine on psychotic symptoms in patients with treatment-resistant (TR) schizophrenia (SCZ) in short-term studies is well established. However, prospective studies of the long-term outcome of clozapine treatment on psychopathology, cognition, quality of life, and functional…