392,304 papers found

BACKGROUND: Although publication bias is a concern when using meta-analysis, techniques for assessing for its potential appear to be underused in nursing. OBJECTIVES: To demonstrate several methods, both graphical and statistical, of assessing for publication bias. METHODS: Four methods are described and demonstrated…

Empirical Bayes meta-analysis provides a useful framework for examining test validation. The fixed-effects case in which rho has a single value corresponds to the inference that the situational specificity hypothesis can be rejected in a validity generalization study. A Bayesian analysis of such a case provides a simpl…

Meta-analysis is a systematic, quantitative approach to the combination of data from several clinical trials that address the same question. This analytic approach can help resolve questions that remain unclear from the results of individual trials. Meta-analysis is of particular interest in oncology because of the sma…

The overall effect of antihypertensive drug treatment has been well documented. The proportion of patients who benefit varies according to their baseline cardiovascular risk, and is small for the majority of people treated. Some investigators propose limiting the treatment target population to patients at high cardiova…

The paper discusses some of the most common criticisms to meta-analysis presented by Professor Feinstein in this Conference. As many of the points raised in his contributions are not new, a critique to them is presented in the context of the type of contribution given by systematic reviews (meta-analysis) to the analys…

Meta-analysis is a technique for summarizing the results of many studies which can allow reviewers in a particular field to arrive at a synthesis of the various findings in a more objective manner than relying on expert opinion and combine the results of these studies to arrive at an overall estimate of the magnitude o…

Bowen's disease frequently has been reported to be associated with internal malignancy, although this association has been extremely controversial. The present study uses the technique of meta-analysis to address this issue by pooling the results of the 12 studies published in the English-language literature that previ…

A meta-analysis of studies on consumer satisfaction with medical care yielded 221 studies that reported relations between satisfaction and other variables, of which 107 reported satisfaction levels for two or more aspects of medical care. A method was developed to derive the relative levels of patient satisfaction with…

The standard estimator for the log odds ratio (the unconditional maximum likelihood estimator) and the delta-method estimator for its standard error are not defined if the corresponding 2 × 2 table contains at least one "zero cell". This is also an issue when estimating the overall log odds ratio in…

We present the R package and web app statcheck to automatically detect statistical reporting inconsistencies in primary studies and meta-analyses. Previous research has shown a high prevalence of reported p-values that are inconsistent - meaning a re-calculated p-value, based on the reported test statistic and degrees…

INTRODUCTION: Meta-analysis is the cornerstone of robust biomedical evidence. OBJECTIVES: We investigated whether statistical reporting practices facilitate metabolomics meta-analyses. METHODS: A literature review of 44 studies that used a comparable platform. RESULTS: Non-numeric formats were used in 31 studies.&#x…

The current paper is a call for and illustration of a way of closing the gap between basic research and professional practice in the field of neurorehabilitation. Methodologically, single-case experimental designs and the guidelines created regarding their conduct are highlighted. Statistically, we review two data anal…

This article is the first in a series of six articles related to systematic reviews in animal agriculture and veterinary medicine. In this article, we overview the methodology of systematic reviews and provide a discussion of their use. Systematic reviews differ qualitatively from traditional reviews by explicitly defi…

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Wei SM, Zhu Y, Wei JX, Zhang CN, Shi JY, Lai HC. Accuracy of dynamic navigation in implant surgery: A systematic review and meta-analysis. Clin Oral Implants Res. 2021 Apr;32(4):383-393. doi: 10.1111/clr.13719. SOURCE OF FUNDING: Shanghai Jiao Tong University School of Medi…

AIM: Bayesian statistical methods can allow for more complete and accurate incorporation of evidence in meta-analyses. However, these methods remain under-utilized. METHODS: A scoping review was conducted to examine the proportion of biomedical meta-analyses that used Bayesian methods in the period 2005-2016. The revi…

Incretin-based therapies are normally prescribed to individuals with type 2 diabetes but has recently come under scrutiny due to the possibility of associated pancreatitis. A 2014 systematic review published in the BMJ found no increase risk of acute pancreatitis in adults with type 2 diabetes, as partly evident from t…

Meta-analytic structural equation modeling (MASEM) combines the techniques of meta-analysis and structural equation modeling for the purpose of synthesizing correlation or covariance matrices and fitting structural equation models on the pooled correlation or covariance matrix. Both fixed-effects and random-effects mod…

In the last decade, a new method has emerged called 'network meta-analysis' to take into account all randomized trials in a given clinical setting to provide relative effectiveness between different treatments, whether or not they have been compared (pairwise) in randomized controlled trials. Network meta-analyses comb…

Conventional random-effects models in meta-analysis rely on normal approximations and fixed within-study variance assumptions that are often violated in rare-event settings. When zero cells occur, Haldane-type (+0.5) corrections can further bias the estimated effects. To overcome these limitations, likelihood-based app…