44,768 papers found

The intestinal microbiome plays a fundamental role in canine health and well-being, regulating functions, including digestion, immunity, metabolism, and behavior. Dysbiosis refers to the disruption of the balanced composition of resident commensal communities, and gut bacteria can influence behavior via neurological, m…

Gynecological cancers, such as vulvar, cervical, endometrial, and ovarian cancers, are the leading causes of morbidity and mortality among women globally. Conventional management modalities like chemotherapy, surgery, and radiotherapy have achieved limited success due to adverse side effects, resistance development, an…

Penile prosthesis (PP) infection is uncommon but serious. Laminar airflow/ultraclean ventilation (LAF/UCV) aims to reduce airborne bioburden, but its clinical impact on PP infection is unclear. We registered a protocol in PROSPERO (CRD420251128507) and followed PRISMA 2020/PRISMA-S, searching MEDLINE (PubMed), Embase (…

OBJECTIVE: To explore the influence of choline and its derivatives (betaine, phospholipids) on the occurrence and development of neural tube defects. METHODS: A narrative review of the available research evidence (including both animal and human studies), based on literature identified through structured searches of d…

The increasing worldwide problem of bacterial infections caused by multidrug-resistant Gram-negative and Gram-positive pathogens has led to consideration of intravenous fosfomycin, especially in combination antimicrobial regimens. We performed a systematic review of the evidence from comparative and non-comparative stu…

BACKGROUND: Substance use during pregnancy is a complex issue with significant implications for both maternal and foetal health. The prevalence of substance abuse among pregnant women varies across age groups and regions, and its associations with adverse developmental outcomes are well-established. Understanding the i…

OBJECTIVES: Chronic pain is a common healthcare issue among adults. It is not only correlated with structural impairments; it is also strongly influenced by psychological and social factors. This study aimed to identify risk factors for the onset of musculoskeletal chronic pain in adulthood during the periods of birth,…

BACKGROUND: Prediabetes, marked by elevated blood glucose levels below the type 2 diabetes mellitus (T2DM) threshold, is a growing public health concern due to its rising prevalence and risk of progression to diabetes and cardiovascular issues. Structured weight loss programs in primary care show promise for improving…

OBJECTIVE: Despite the high demand for speech and language therapy (SLT) for children with speech sound disorders (SSDs), accessible services remain limited. Technology-driven efforts have led to the development of systems and applications to assist children, parents, and therapists in the SLT process. AI and machine l…

Quality of nursing care (QNC) is a central concept in healthcare systems worldwide, with growing emphasis on developing reliable and contextually appropriate instruments for its assessment. Over recent decades, there has been a shift from outcome-based evaluation toward more holistic, patient-centered frameworks that c…

BACKGROUND: Infertility is a global reproductive health concern that imposes intense psychological and social burdens, particularly in cultural contexts where childbearing is integral to the construction of womanhood. OBJECTIVE: This qualitative meta-synthesis aimed to gain an in-depth understanding how women experien…

INTRODUCTION: To understand brain function, diverse approaches are pursued. The influence of movements on brain activity has been part of this research for decades. Recent advancements in electroencephalography (EEG) coupled with a shift in focus toward the effects of complex whole-body movements provided additional in…

PURPOSE: The purpose of this review is to discuss the role of fat-soluble vitamins in bone metabolism and explore whether there is a relationship between each fat-soluble vitamins in the occurrence and development of osteoporosis. METHODS: We selected several databases, including PubMed, PubMed Central (PMC), Embase,…

Self-report measures have been used as a tool to evaluate mania and depressive symptoms and aid in diagnosing bipolar disorder. The American Medical Association recommends that the evaluation reading be at a fifth- to sixth-grade level. The research literature has previously established that questionnaires regarding ot…

The prevalence of recidivism among individuals with a history of substance use and incarceration remains a significant concern for criminal justice systems worldwide. With significant social and economic ramifications, preventing people with a history of substance use from reoffending is a substantial issue. It is impe…

INTRODUCTION AND OBJECTIVE: In every society there are people who have the legal or biological status of a disabled person. There are 1.3 billion people worldwide who require assistance and support at every stage of their medical treatment and rehabilitation. Their social needs are underestimated, which reduces their q…

Restless legs syndrome is a neurological disease from the spectrum of movement disorders, with psychiatric comorbid symptoms and manifestations. Women are affected twice as often as men, and the frequency in the population is 4-10%, while during pregnancy the prevalence triples. This research was conducted as a result…

This systematic review examined the accuracy and efficiency of AI-based automated tooth segmentation methods compared to manual or ground truth techniques. A comprehensive search was conducted in MEDLINE (via PubMed), the Cochrane Central Register of Controlled Trials, ScienceDirect, SciELO, LILACS, the German National…

22q11.2 deletion syndrome (22q11.2DS) is one of the most common congenital malformation syndromes resulting from disrupted embryonic development of pharyngeal pouches. The classical triad of symptoms described by Angelo DiGeorge is frequently accompanied by hematological and immune disorders. While it is well-establish…

BACKGROUND: The choroid, a highly vascular structure within the eye, is significantly influenced by various systemic conditions. The advent of enhanced depth optical coherence tomography has improved our ability to evaluate choroidal pathophysiology. The choroidal vascularity index (CVI), a noninvasive and reliable too…