11,612,200 papers found

Congenital Adrenal Hyperplasia (CAH) is a group of diseases with an autosomal recessive inheritance pattern, which are caused by a defect in the enzymes involved in steroidogenesis in the adrenal cortex. Depending on the enzyme block variant, the spectrum of clinical manifestations of CAH varies from mild symptoms to p…

BACKGROUND: Choroidal and ciliary body melanomas divide into two approximately equal groups. Local therapy cures one group while the other metastasizes and proves lethal. Monosomy 3 strongly associates with aggressive behavior. We analyzed a series of choroidal and ciliary body melanomas to describe the cellular featur…

BACKGROUND: Early risk stratification in acute ischemic stroke (AIS) is critical for guiding management and improving outcomes. The ratio of non-high-density lipoprotein to high-density lipoprotein cholesterol (NHHR) represents the equilibrium between pro-atherogenic and anti-atherogenic lipoproteins, potentially captu…

Myopia is a global public issue with a dramatically increasing incidence. Myopia is currently characterized by its earlier onset, quick development in preschool (0-5 years old), and continued progression particularly during the coronavirus-19 epidemic phase. It has been established that myopia experienced during childh…

PURPOSE: This study's objective was to investigate the effects of programs that improve adolescents' body image, using a systematic review and meta-analysis. METHODS: A literature search was performed in eleven electronic databases, using preferred reporting items for systematic reviews and meta-analysis guidelines. P…

Diabetic foot ulcer (DFU) is a common complication in the advanced stages of diabetes mellitus. DFU in these individuals cannot heal properly over time due to microcirculatory changes that hinder and stagnate the healing process. There is a wide range of therapeutic strategies for DFU, but only minimal efficacy has bee…

OBJECTIVE: Autologous adipose injection (AAI) is a recognized method for vocal fold augmentation. The study's purpose is to explore short- and long-term outcomes of AAI. METHODS: Retrospective chart review of 43 patients undergoing AAI was performed; patient perception of outcome, Voice Handicap Index (VHI), maximum p…

The mismatch between students and school furniture is likely to result in a number of negative effects, such as uncomfortable body posture, pain, and ultimately, it may also affect the learning process. This study's main aim is to review the literature describing the criteria equations for defining the mismatch between…

UNLABELLED: Relatively little is understood regarding the aetiology of bipolar disorder (BD) other than for the influence of a large genetic component on the development of the disorder and the impact of stressful life events on changes in current mood. However, amongst a range of psychiatric diagnoses, research consis…

BACKGROUND: Many patients with quiescent ulcerative colitis (UC) experience relapse. However, clinical and conventional colonoscopic signs are inadequate for predicting relapse. This study's aim was to investigate the effectiveness of magnifying colonoscopy in predicting relapse in patients with quiescent UC and to eva…

AIMS: Oral naltrexone is used in the management of both heroin and alcohol dependence. However, poor compliance has limited its clinical utility. The study's objective was to determine the period of therapeutic coverage (>or=2 ng/ml) provided by a 3.3 g naltrexone subcutaneous implant compared with existing data on 1.1…

Cancer limits survival following heart transplantation. The study's objectives were to evaluate the incidence and risk factors for cancers after heart transplantation and to assess the association between i.v. thymoglobuline induction therapy [rabbit antithymocyte immunoglobulin, (RATG)] and neoplasia. From 1982 to 200…

PURPOSE: To evaluate the safety and efficacy of phacoemulsification, primary posterior capsulorhexis (PCCC), and primary intraocular lens (IOL) implantation for uveitic cataracts. SETTING: Institutional practice. METHODS: Fifteen consecutive eyes of 13 patients with various causes of uveitis received anterior capsulo…

PURPOSE: Gliomatosis cerebri (GC) is defined as a diffusely infiltrative pattern of growth affecting at least three contiguous lobes of the brain. GC presents unique challenges in terms of surgery and radiation therapy. We evaluated the genomic determinants of GC. METHODS: In this retrospective study, we evaluated gene…

PURPOSE: The study's aim was to report prevalence estimates and age-related trends in refractive error in a clinic-based series and compare them to results from studies of a similar nature conducted since 1892. METHODS: Refractive error, patient age, and sex were collected from the files of all patients seen at the Un…

BACKGROUND: The research and development of augmented-reality (AR) technologies in surgical applications has seen an evolution of the traditional user-interfaces (UI) utilised by clinicians when conducting robot-assisted orthopaedic surgeries. The typical UI for such systems relies on surgeons managing 3D medical imagi…

Self-perceived status is considered an important antecedent of an employee's extra-role behavior. However, the relationship between self-perceived status and "proactive helping" has been neglected in previous human resource management (HRM) research. Data were collected from 214 employees and their supervisors in two w…

BACKGROUND AND OBJECTIVES: Tumor location and eloquence are two crucial preoperative factors when deciding on the optimal treatment choice in glioma management. Consensus is currently lacking regarding the preoperative assessment and definition of eloquent areas. This systematic review aims to evaluate the existing def…

BACKGROUND: Sibling bonds are often the most enduring relationship in an individual's life span. The out-of-home placement of siblings is widespread and may significantly influence children's journeys and wellbeing. OBJECTIVE: The current scoping literature review was designed to characterize and analyze the existing…

PURPOSE: To evaluate the recurrence rate of odontogenic keratocyst (OKC) after treatment with 5-fluoracil as an adjunctive therapy and to evaluate, as well, the efficacy of this medication in reducing the incidence of inferior alveolar nerve paresthesia associated with other chemotherapeutic agents. MATERIAL AND METHO…