5,042,053 papers found

Systematic reviews seek to bring together research evidence to answer the question for the review. The reviewers usually wish to compare, contrast and, if appropriate, combine the findings of the existing research studies. However, these intentions are often thwarted by inconsistencies in the outcomes that were measure…

The aim of this article is to perform an inventory on the subject of rapid reviews.Carrying out a systematic review or health technology assessment (HTA) is costly and time-consuming. Usually, it takes between six months and one year to complete a systematic review, and at least one year to complete an HTA. Since quest…

OBJECTIVES: The objective of the study is to examine the time from publication of the protocol for a Cochrane review to publication of the Cochrane review for the entire Cochrane Database of Systematic Reviews (CDSR). STUDY DESIGN AND SETTINGS: Cochrane reviews from the CDSR published between 1995 and 2019 were assess…

Schools are identified as a key setting to influence children's and adolescents' healthy eating. This umbrella review synthesised evidence from systematic reviews of school-based nutrition interventions designed to improve dietary intake outcomes in children aged 6 to 18 years. We undertook a systematic search of six e…

Systematic Review Briefs provide a summary of the findings from systematic reviews developed in conjunction with the American Occupational Therapy Association's Evidence-Based Practice Program. Each systematic review brief summarizes the evidence on a theme related to a systematic review topic. This systematic review b…

Systematic reviews and meta-analyses are powerful tools for summarizing existing literature and combining evidence from multiple studies. These methods employ complex searches, statistical techniques, and presentation techniques with which the clinical audience may not be very familiar. This review article aims to fami…

BACKGROUND: Workplaces are an important setting to deliver programs to reduce risk factors for noncommunicable diseases (NCDs). To help decision makers understand the most current and relevant evidence regarding effectiveness of workplace programs, we conducted an umbrella review to present a comprehensive synthesis of…

RATIONALE AND AIM: Clear and logical eligibility criteria are fundamental to the design and conduct of a systematic review. This methodological review examined the quality of reporting and application of eligibility criteria in systematic reviews published in three leading medical journals. METHODS: All systematic rev…

Placebo responses to an apparently inactive intervention are of interest from a scientific perspective as they suggest possible mechanism(s) at work beyond the intervention itself. They are also of interest from a clinical trials perspective since high rates of placebo response limit the potential to demonstrate worthw…

OBJECTIVES: To support systematic reviewers new to network meta-analysis (NMA), we (1) identified and described published methods resources for conducting systematic reviews (SRs) with NMA of randomized controlled trials (RCTs); (2) mapped the resources to the typical steps for conducting NMAs; and (3) identified NMA g…

BACKGROUND: Systematic reviews (SRs) and realist reviews (RRs) are increasingly conducted in a coordinated manner with intersecting methodological processes, forming what we term hybrid review designs. However, little is known about how these hybrid reviews are conducted and structured. OBJECTIVES: This study aimed to…

INTRODUCTION AND OBJECTIVE: The number of literature reviews examining the use of social media in detecting emerging infectious diseases has recently experienced an unprecedented growth. Yet, a higher-level integration of the evidence is still lacking. This study aimed to synthesize existing systematic literature revie…

BACKGROUND: Oral care is a fundamental part of nursing but it is often performed as a routine task, often based on historic practice, and lacks an evidence base. A variety of oral care products are used in practice. AIM: To discover evidence of effective oral care products for use in hospitalised patients. DESIGN: A…

Systematic reviews provide a synthesis of evidence for a specific topic of interest, summarising the results of multiple studies to aid in clinical decisions and resource allocation. They remain among the best forms of evidence, and reduce the bias inherent in other methods. A solid understanding of the systematic revi…

This narrative review analyses the Australian Guideline (2018) for the treatment of knee osteoarthritis (KOA) developed using Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. The Guideline recommended against the use low-level laser therapy (LLLT). Why this conclusion was reached…

Objective Meeting the mental health needs of the population is a priority of the Quebec government. To do so, it is important to evaluate and improve the quality of mental health care in primary and community care settings, particularly with respect to person-centred and recovery-oriented care. The purpose of this stud…

This review highlights clinically important findings about acne treatment identified in nine systematic reviews published or indexed in the period March 2009 to February 2010. A systematic review of dietary influences on acne suggested that a possible role of dietary factors in acne cannot be dismissed, as the studies…

PURPOSE OF REVIEW: The term 'evidence-based medicine' means integrating individual clinical expertise with the best available external clinical evidence from systematic research. An important source for those who wish to practise evidence-based medicine is the systematic review. Systematic reviews, however, are not wit…