42,458 papers found

Child marriage, defined as the union of a child under 18 years with an adult or another child, remains a pervasive issue globally, particularly in sub-Saharan Africa. Despite international efforts to eradicate this practice, approximately 15 million girls marry before 18 annually, infringing on their basic human rights…

BACKGROUND: Rapid population aging has increased the demand for integrated care for older adults, particularly in rural areas where older adults frequently experience chronic illness, frailty, and limited access to healthcare. Caregivers, both formal and informal, play a central role in supporting the wellbeing of olde…

BACKGROUND: Midwives are essential providers of maternal and neonatal healthcare, particularly in sub-Saharan Africa, where they play a crucial role in managing obstetric complications and improving maternal and child health outcomes. Despite their significance, limited research has explored their lived experiences in…

BACKGROUND: Risperidone, a second-generation antipsychotic with strong alpha-1 adrenergic receptor affinity, has been associated with priapism, a rare but serious urological emergency. This adverse effect remains underrecognized in psychiatric settings. We synthesized published reports on risperidone-induced priapism,…

Growth hormone deficiency (GHD) is a prevalent consequence of traumatic brain injury (TBI) that can contribute to prolonged adverse symptoms and impaired quality of life. The overlap between symptoms of GHD and chronic TBI complicates the clinical picture, highlighting the need for precise diagnostic tools. Insulin-lik…

Varicose veins are a common disease worldwide, mainly affecting adults, and are estimated to be the 7th most common reason for physician referral in the USA. There is no ideal technique for treatment of varicose veins. Several techniques have emerged in recent years: the most widely used are thermal techniques such as…

BACKGROUND: Ferroptosis is a form of programmed cell death triggered by iron-dependent lipid peroxidation. Accumulating evidence has revealed potential associations between cellular Ferroptosis and infection, inflammation, and immunity. Given the substantial literature in this field, the present study aims to comp…

PURPOSE: To evaluate five-year survival rates of metal-ceramic, veneered all-ceramic, and monolithic all-ceramic tooth-supported single crowns (SCs) and assess biological and technical complications. MATERIALS AND METHODS: A systematic search of Medline (PubMed), Embase, and CENTRAL (2014-2024) identified clinical stu…

BACKGROUND: Frailty is a prevalent geriatric syndrome associated with risk of disability, hospitalization, and mortality. Despite nutrition and exercise playing central roles in maintaining muscle mass and function, the specific effects of nutritional guidance, distinct from supplementation, remain unclear. OBJECTIVE:…

Heutagogy, or self-determined learning, is an emerging educational framework that emphasizes learner autonomy, capability development, and reflective practice. Unlike pedagogy and andragogy, heutagogy places learners in control of their learning goals, strategies, and outcomes, fostering adaptability and lifelong learn…

Longevity and healthy aging result from the complex interaction of genetic, epigenetic, microbial, behavioral, and environmental factors. The central nervous system-particularly the cerebral cortex-and the autonomic nervous system (ANS) play key roles in integrating external and internal signals, shaping energy metabol…

Data on the genetics and molecular biology of diabetes are accumulating rapidly. This poses the challenge of creating research tools for a rapid search for, structuring and analysis of information in this field. We have developed a web resource, GlucoGenes®, which includes a database and an Internet portal of gene…

INTRODUCTION: Obesity, affecting 38% of adults globally, carries economic burdens and health risks like cardiovascular disease and diabetes. Weight-loss programs often face challenges due to stigma and poor body image, impacting individuals' quality of life. Research on interventions targeting weight stigma is lacking,…

INTRODUCTION: The aim of this systematic review was to determine the best treatment alternatives for patients with maxillary lateral incisor agenesis (MLIA) by comparing orthodontic space closure, implant and tooth supported dental prostheses by assessing studies that evaluated their periodontal, occlusal (function) an…

: Physiotherapy plays a key role in managing fibromyalgia, a multifaceted disorder, through a combination of active and passive treatments. The purpose of this review is to compare the efficacy of "hands-off" treatments alone versus the combination of "hands-off" and "hands-on" therapies.: MEDLINE (PubMed), CENTRAL, an…

INTRODUCTION: Cataract is a leading cause of visual impairment and blindness, mainly affecting older adults in sub-Saharan Africa (SSA). This scoping review aims to map evidence on the prevalence, contextual factors, and management strategies for cataracts among older adults in SSA. METHOD: Four central databases (Pub…

Hypertension, defined as persistently elevated blood pressure, is a prevalent chronic condition and a significant global health issue, closely linked to cardiovascular complications, with inflammation being one of the underlying mechanisms. In hypertensive patients, C-reactive protein (CRP), an inflammatory marker, is…

INTRODUCTION: Primary health care is a key element in the structuring and coordination of health systems, contributing to overall coverage and performance. PHC financing is therefore central in this context, with variations in sufficiency and regularity depending on the "political dimension" of health systems. Research…

: This research aims to synthesize existing data on the evidence gap in scar treatment and evaluate the effectiveness of acupuncture and dry needling in treating scars and related symptoms.: The article adhered to the PRISMA 2020 statement for recommended reporting elements in systematic reviews. The inclusion criteria…

This article aims to present the overview of the situation during the coronavirus disease 2019 (COVID-19) pandemic about issues concerning the prevalence of mental disorders such as depression, anxiety, rate of suicide attempts, and long COVID (LC) infections in the general population during COVID-19 pandemic. Analysis…