Metformin and health outcomes: An umbrella review of systematic reviews with meta-analyses.
Li Xue, Celotto Stefano, Pizzol Damiano, +14 more·European journal of clinical investigation
BACKGROUND: The objective was to capture the breadth of outcomes that have been associated with metformin use and to systematically assess the quality, strength and credibility of these associations using the umbrella review methodology. METHODS: Four major databases were searched until 31 May 2020. Meta-analyses of o…