A clinical trial of Tofranil in rheumatic pain in general practice.
Gringras M·The Journal of international medical research
A multicentre double-blind clinical trial was conducted in general practice in which imipramine (Tofranil) was added to existing standard analgesic anti-rheumatic therapy in patients suffering from osteo-arthritis, rheumatoidtero-arthritis, rheumatoid arthritis or ankylosing spondylitis. Twelve doctors admitted sixty-f…