5,010,811 papers found

The International Liaison Committee on Resuscitation has initiated a continuous review of new, peer-reviewed, published cardiopulmonary resuscitation science. This is the second annual summary of International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommenda…

BACKGROUND: The promotion of health equity, the absence of avoidable and unfair differences in health outcomes, is a global imperative. Systematic reviews are an important source of evidence for health decision-makers, but have been found to lack assessments of the intervention effects on health equity. The Preferred R…

OBJECTIVE: To report on the progress of an ongoing research collaboration on magnetic resonance imaging (MRI) in juvenile idiopathic arthritis (JIA) and describe the proceedings of a meeting, held prior to Outcome Measures in Rheumatology (OMERACT) 12, bringing together the OMERACT MRI in JIA working group and the Heal…

Consensus methods are increasingly being used in healthcare research, particularly for formulating policy and strategic directions. This paper by Elizabeth Halcomb, Patricia Davidson and Laura Hardaker discusses the issues central to the planning and conduct of the consensus development conference, and offers practical…

The European Society of Mastology (Eusoma) is committed in writing and diffusing guidelines on Breast Cancer, aiming at harmonising the quality of Breast Cancer care throughout Europe. To achieve this Eusoma organises scientific meetings, "workshops" or "Consensus meeting", inviting European experts from the different…

OBJECTIVE: To clarify the grading of recommendations assessment, development and evaluation (GRADE) definition of certainty of evidence and suggest possible approaches to rating certainty of the evidence for systematic reviews, health technology assessments, and guidelines. STUDY DESIGN AND SETTING: This work was carr…

BACKGROUND: Around 16% of adults have symptoms of overactive bladder (OAB; urgency with frequency and/or urge incontinence), with prevalence increasing with age. Anticholinergic drugs are commonly used to treat this condition. This is an update of a Cochrane Review first published in 2002 and last updated in 2006. OBJ…

Delivery room resuscitation guidelines evolved in the late 1980s in the United States, based largely on clinical experience with some supportive experimental evidence. Subsequently over time, there has been an increasing emphasis toward the practice of evidence-based medicine. Despite difficulties in conducting researc…

Despite a large number of published randomized prospective controlled clinical trials the indications for perioperative parenteral and enteral nutrition support remain controversial. This article reviews the reports of several recently published consensus conference reports and prospective randomized controlled trials…

Obesity is a chronic non-communicable disease; that significantly impacts cardiovascular health via related conditions such as hypertension, diabetes, and coronary artery disease. Bariatric surgery provides effective weight loss, however exercise's cardiometabolic benefits post-surgery remain underexplored. To gain dee…

INTRODUCTION: Bone marrow aspirate concentrate (BMAC) is increasingly used in orthopaedics for its regenerative potential. As clinicians rely on systematic reviews and meta-analyses to guide clinical decision making, concerns remain regarding methodologic rigor and reporting bias (spin). This study evaluated the preval…

PURPOSE: This guideline aimed to make evidence-based clinical practice guidelines for the primary treatment of temporomandibular disorders (TMDs) for general practitioners who do not specialize in TMD. REVIEW PROCESS: Following the principles of evidence-based medicine, a systematic review and network meta-analysis (N…

BACKGROUND: Meta-analyses of the voluminous scientific literature on the impact of very preterm (VPT, <32&#x2009;weeks' gestation) birth on cognition find a marked deficit in intelligence quotient (IQ) among children born VPT relative to term-born peers, but with unexplained between-study heterogeneity in effect size.…

: Consequences due to infection with SARS-CoV-2 virus can have a direct impact on skeletal muscle, due to the fact that both cardiac and skeletal muscle tissue show robust ACE2(angiotensin-converting enzyme 2) expression, suggesting a potential susceptibility to SARS-CoV-2 infection in both types of tissues. From the a…

Introduction: Armed conflicts affect the mental health of children and adolescents. Their outcomes in these populations have been documented identifying vulnerability and significant biopsychosocial damage as the most common factors. Objective: To identify and synthesize the mental health consequences of armed conflict…

Hepatitis C virus and chronic kidney disease are major public health issues all over the world and controversy persists regarding the role of Hepatitis C as a risk factor for the development of chronic kidney disease in the adult general population. Numerous studies found a relationship between positive anti-HCV antibo…