98,346 papers found

In a double-blind crossover study, 16 hypertensive patients (mean age, 41 years) were randomly assigned to receive placebo or 5 mg of an extended-release formulation of isradipine for 30 days. Blood pressure and heart rate were recorded by an automatic device and hemodynamics measured by a duplex scanner and plethysmog…

INTRODUCTION: Bordetella pertussis infections have resurged globally, posing notable public health challenges, particularly in pediatric populations. Poland remains the only EU country that continues to use the whole-cell pertussis vaccine (wP) in routine immunization. This study evaluated the vaccination status and di…

OBJECTIVE: This study aimed to evaluate the knowledge and clinical awareness of local anesthetic systemic toxicity (LAST), preventive practices, knowledge of lipid emulsion therapy, and institutional availability among dentists actively practicing in Türkiye, and to examine the demographic and professional factors…

UNLABELLED: Purpose Paget' s osteosarcoma has a fearful reputation with a quoted survival of at best 5% at 5 years.We therefore reviewed our experience of 26 patients treated over the last 25 years using modern staging and limb salvage techniques to see if there had been any improvement in survival. SUBJECTS: We ident…

PURPOSE: To evaluate long-term outcomes after photorefractive keratectomy (PRK). METHODS: A retrospective follow-up study of patients who received PRK at 5.0- to 6.5-mm optical zones, using the Summit broad beam excimer laser (Summit Technology, Inc., Waltham, MA) at Odense University Hospital, Odense, Denmark, betwee…

PURPOSE: To describe the clinical outcome and late-stage findings of extensive macular atrophy with pseudodrusen-like appearance (EMAP). DESIGN: Retrospective cohort study. PARTICIPANTS: Seventy-eight patients (156 eyes) affected by EMAP. METHODS: We collected data on best-corrected visual acuity, kinetic perimetry,…

Microrefugia at high altitudes or high latitudes are thought to play an important role in the post-glacial colonization of species. However, how populations in such microrefugia have responded to climate changes in alternating cold glacial and warm interglacial stages remain unclear. Here we present evidence to indicat…

Radiofrequency (RF) ablation has gained great popularity in the treatment of Hepatocellular Carcinoma (HCC) on cirrhosis and is replacing Percutaneous Ethanol Injection (PEI) in treating 3 cm or less HCC nodules. Its necrotic effect is more predictable than that of PEI and therefore RF can achieve a longer local tumor…

INTRODUCTION: The main objective of the study was to assess return to sports in recreational athletes after arthroscopic repair of rotator cuff tear (RCT). MATERIAL AND METHODS: A retrospective single-center study included all recreational athletes operated between 2008 and 2012 for arthroscopic repair of RCT, with re…

This issue of the Journal of Neurology and Psychiatry named after S.S. Korsakov is devoted to multidisciplinary aspects of depression and suicidal behavior. This issue is devoted to the multidisciplinary aspects of the study of depressive states and suicidal behavior. Despite the great attention paid to the problem of…

BACKGROUND CONTEXT: We previously reported the preliminary results of minimally invasive anterior lumbar interbody fusion (mini-ALIF) with percutaneous pedicle screw fixation (PPF) in 2004. PURPOSE: To investigate the long-term results of mini-ALIF followed by PPF for the treatment of back and leg pain in adult isthmi…

Twenty-one patients between the ages of 8 and 12 years with 23 femoral-shaft fractures underwent dynamic compression plating (DCP) between August 1993 and February 1996. Eleven patients had isolated femoral-shaft fractures, five had associated long-bone injuries, and five had multiple organ injuries. A 4.5-mm DCP plate…

This method of treating hemorrhage from ruptured esophageal varices gives excellent results in cases usually reserved for treatment by portocaval shunts, as well as patients with the usual contraindications to shunt operations. If it is possible without transfusion, and with a single assistant, to definitely stop hemor…

BACKGROUND: Use of the antiepileptic drug vigabatrin is associated with an elevated risk of visual field loss. OBJECTIVE: To determine the frequency of, and risk factors for, vigabatrin-attributed visual field loss (VAVFL) in the setting of a large-scale, multinational, prospective, observational study. STUDY DESIGN:…

In 2009, 2 390 cases of pertussis were reported in Poland. The incidence 6.3 per 100 000 was higher, 9.5% more compared to the last year (5.7). Highest incidence 38.1 per 100 000 population was observed in 3 years old children and like last year in 10-14 age group (34.7) and among urban areas population. Of 2 390 cases…

BACKGROUND: Use of electroconvulsive therapy (ECT) may have changed during the last decades due to advances in psychopharmacology and organizational changes of psychiatric care. OBJECTIVES: To identify predictors for receiving ECT for the first time and to describe temporal trends in ECT utilization. METHODS: A regis…

In this study, we evaluated the results in four patients with nongerminomatous germ cell tumors (NGGCT) of the pineal region. All underwent radiosurgery in conjunction with surgical resection, fractionated radiotherapy or chemotherapy. Four male patients with pineal region NGGCT were treated with radiosurgery. The mean…

To clarify the environmental factors regulating the annual reproductive cycle of the female mosquitofish, Gambusia affinis, a viviparous teleost, histological changes of the ovary in natural population, and laboratory experiments were examined. The results, extending over two years, suggested that ovarian recrudescence…

INTRODUCTION: HIV/AIDS is a major global public health concern. In Pernambuco state, Brazil, the number of people living with HIV/AIDS (PLWHA) is among the highest in the country. Herein, a cross-sectional retrospective observational study was carried out with 811 PLWHA followed up at the Clinical Hospital, Pernambuco,…

PURPOSE: The purpose of this study was to report the long-term outcomes of Descemet membrane endothelial keratoplasty (DMEK) with goniosynechialysis in eyes with iridocorneal endothelial syndrome with an emphasis on the surgical technique. METHODS: This was a retrospective series of 5 eyes of 5 patients undergoing a D…