97,510 papers found

Colorectal cancer (CRC) is the third most common cancer type in humans, the fourth most common cause of death because of cancer, and the second most common cancer type in terms of the number of individuals living with cancer 5 years after diagnosis worldwide, almost 694,000 people die from CRC annually. As it is expect…

Ten patients with Bloom's syndrome observed in Germany during the last 20 years are described. They were born between 1964 and 1986. Seven are alive at the age of 8 to 27 years. Three have died at the age of 5 years (acute leukemia), 18 years (pulmonary fibrosis and bronchiectasis), and 21 years (Hodgkin lymphoma and s…

BACKGROUND: Paliperidone palmitate 3-monthly (PP3M) is a second-generation, long-acting injectable antipsychotic formulation indicated for the maintenance treatment of adults with schizophrenia first stabilized with paliperidone palmitate 1-monthly (PP1M). This exploratorysubgroup analysis of the 52-week, phase 3b REMI…

In recent years, there has been increasing recognition that akathisia occurs not only as an acute, self-limited complication of dopamine (DA) antagonist treatment, but also as a persistent form, called tardive akathisia. We represent a retrospective analysis of clinical features and therapeutic trials in 52 cases of th…

The results of treatment of 629 previously untreated adults with acute leukemia at Memorial Hospital are reviewed. During the past 14 years, 135 adults (greater than 15 years) with acute lymphoblastic leukemia (ALL) have been treated with one of three successive multidrug-intensive treatment protocols (L2, L10/10M, and…

Over the past 10 years, increasing evidence has accumulated that heterogeneity is a feature of hematopoietic stem cell (HSC) proliferation, self-renewal, and differentiation based on examination of these properties at a clonal level. The heterogeneous behavior of HSCs reflects the operation of a complex interplay of in…

For the first two decades, leukemic chemotherapy had little impact on survival. In the past 10 years, however, remission induction therapy has generated complete remissions which last approximately one year in about half to three fourths of those treated, with a seventh in some series alive at 5 years.

On the basis of critical survey of literature data and analysis of morbidity of intestinal infections in 5 towns of Donbass for 20 years and also of studying 5148 case histories an attempt is made of rational explantation of the causes of growth during the last years of the incidence of Sonne dysentery salmonelloses, e…

BACKGROUND: Data during the last decade show that laparoscopic nephrectomy is becoming an accepted and advantageous minimally invasive alternative to the open procedure. OBJECTIVE: To evaluate the efficacy, safety and reproducibility of laparoscopic nephrectomy in a series of 110 consecutive procedures. METHODS: A to…

Aim of the study was the comparison of quality of life after multiple injury using limitations of handicaps--social roles, ICIDH (World Health Organization). The study group comprised 1259 patients in the years 1989-2003 whose degree of injuries amounted to at least 18 scores in the Injury Severity Scores. Patients wer…

PURPOSE OF REVIEW: Laparoscopic partial nephrectomy (LPN) technique has continually evolved over the last decade, resulting in better outcomes and increased popularity within the urological community. In this article, we provide an overview of the contemporary literature on LPN. RECENT FINDINGS: The technique of LPN h…

Modern vaccines-including influenza vaccine-provide a uniquely powerful and cost-effective way to prevent deadly communicable diseases from spreading. Unfortunately, since the last decade of the 20th century, influenza vaccine supply and distribution problems have steadily grown worse in the United States. Supply disru…

Despite recent advances in the last decade, invasive fungal infections are still associated with a high morbidity and mortality. Invasive fungal infections constitute severe infectious complications in patients with hematological malignancies receiving myelosuppressive chemotherapy or sustained immunosuppression after…

In 1998 further global increase in reported cases of pertussis in Poland was observed. The total number of reported cases was 2871 including 854 cases reported in 1998 which occurred in 1997. Most of the cases accumulated in first quarter of the year, with subsequent decrease in the second half of the year, to the leve…

Epidemiologic programs in Martinique during the last 10 years and particularly the last 5, have allowed the determination of the Hb S, Hb C, beta thalassemia traits frequencies. A number of rare variants have been detected during the course of these screening programs. Many of these Hb variants have been analysed at th…

A study has been carried out on the width of the seminiferous tubules, and the proportion of pre-germinal cells, in 174 stillborn children between 24 and 40 weeks of gestation, and in 146 children dying between the ages of birth and six years. There was a general diminution in the diameter of the seminiferous tubule th…

BACKGROUND: Revision knee arthroplasty with a rotating-hinge design could be an option for the treatment of instability following total knee arthroplasty (TKA) in elderly patients. PURPOSE: To evaluate the clinical and radiographic results of revision arthroplasties in TKAs with instability using a rotating-hinge desi…

In the last 25 years 268 (67%) patients were hospitalized for proper tuberculosis of the skin, and 132 (33%) for tuberculids. In the period 1983-1987 the prevalence of skin tuberculosis was 5.8 times lower than in the period 1963-1967. The frequency of the clinical forms of tuberculosis was as follows: tbc. luposa (57.…

We studied identity development during 5 years in seven deaf adolescents who attended a school for deaf children in the highest level of regular secondary education (age between 14 and 18 years), administering identity interviews every year. Identity development is conceptualized as the processes of exploration and com…

The authors report nine cases of epithelioma occuring on chronic leg ulcers of venous origin (6), or on fistula from chronic osteitis (3). Compared with the other trophic leg ulcers observed during the same period, the risk of malignant change approximatly is of 0,3 p. 100. It always concerns aged caucasian subjects (a…