41,005 papers found

Information Retrieval (IR) plays a central role in the exploration and interpretation of integrated biological datasets that represent the heterogeneous ecosystem of life sciences. Here, keyword based query systems are popular user interfaces. In turn, to a large extend, the used query phrases determine the quality of…

BACKGROUND AND OBJECTIVES: Assess the efficacy of simplified search strategies and identify the best electronic bibliographic database for clinical trials in the field of musculoskeletal disorders and pain. METHODS: Clinical trials within selected reviews from the Cochrane Back, Musculoskeletal, and PaPaS Review Group…

BACKGROUND: One central goal of computational systems biology is the mathematical modelling of complex metabolic reaction networks. The first and most time-consuming step in the development of such models consists in the stoichiometric reconstruction of the network, i. e. compilation of all metabolites, reactions and t…

BACKGROUND: During the last two decades, there has been a significant change in the origin and impact of the world's biomedical scientific production, particularly in countries in which the investment in research accounts for an important portion of the gross national product (GNP). However, in less developed countries…

This paper describes the capabilities of DISCO, an extensible approach that supports integrative Web-based information dissemination. DISCO is a component of the Neuroscience Information Framework (NIF), an NIH Neuroscience Blueprint initiative that facilitates integrated access to diverse neuroscience resources via th…

BACKGROUND: The presentation and academic discussion of the latest scientific research is the central purpose of meetings like the annual meeting of the German Society of Neurosurgery (DGNC). The aim of this study was to investigate the publication rate of all oral and poster abstracts of the DGNC meeting 2012 held in…

BACKGROUND: It is generally believed that exhaustive searches of bibliographic databases are needed for systematic reviews of health care interventions. The CENTRAL database of controlled trials (RCTs) has been built up by exhaustive searching. The CONSORT statement aims to encourage better reporting, and hence indexin…

PURPOSE: The quality of systematic reviews relies on the inclusion of published and unpublished clinical trials. Unpublished trials often report statistically non-significant results, which if included in systematic reviews would likely alter study conclusions. This study aims to evaluate whether systematic reviews in…

INTRODUCTION: Pharmacological treatment is the first that should be taken into account in dealing with neuropathic pain, antiepileptic drugs being one of the leading options. Levetiracetam is a state of the art antiepileptic drug that has displayed antinociceptive activity in experimental models of pain and clinical ef…

To explore the information needs of rural health professionals, a retrospective study was undertaken of 1,224 document delivery requests made during the course of three outreach projects in west and central Illinois. The 547 unique journals from which the articles were requested were analyzed for frequency of request,…

OBJECTIVE: To determine the number, nature, site of publication, and feasibility of identifying randomised controlled trials relevant to primary care. DESIGN: Review of literature using three strategies: approaching journal editors, Medline search, and manual search of individual journals. SETTING: Journals containin…

The authors ask whether full-text versions of medical journals are available for searching sooner than their biblographic counterparts. The journals in question are those found in the Comprehensive Core Medical Library (CCML) from BRS Information Technologies and in Mead Data Central's MEDIS Current Journal Files. All…

Conceptual connections between users and information sources depend on an accurate representation of the content of available information sources, an accurate representation of specific user information needs, and the ability to match the two. Establishing such connections is a principal function of medical librarians.…

Since "Budapest Open Access Initiative" signed in 2002, there have been more and more open-access journals coming out on Internet, thus brining the best condition to the researchers. It has made better the phenomenon of not having enough foreign language periodicals in our country. The present author has selected part…

A powerful method of processing MEDLINE and CINAHL source data uploaded to the IBM 3090 mainframe computer through an IBM/PC is described. Data are first downloaded from the CD-ROM's PC devices to floppy disks. These disks then are uploaded to the mainframe computer through an IBM/PC equipped with WordPerfect text edit…

The compatibility of downloaded MEDLINE references with software packages designed for maintenance of personal bibliographic databases is considered. The nine packages reviewed enable one to import batches of records downloaded from one or more presentations of the MEDLINE database, online or CD-ROM; and enable the use…

Systematic literature search is a fundamental in evidence-based medicine. But systematic literature search is not yet a very well used way of retrieving evidence-based information. This article profiles a systematic literature search for evidence-based literature. It goes through the most central databases and gives an…

The paper analyses the development of the total number of journal articles indexed in the Medline database published by authors affiliated to Denmark 1989-1998 in medicine compared to the development in the European Union during the same period. The publication analysis is then compared to the citation impact of articl…