5,082,504 papers found

BACKGROUND: There is a push to make clinical decision making more evidence based and patient oriented. However, current systematic reviews are limited by the lack of consideration of generalizability. OBJECTIVE: To develop a guide for investigators (systematic reviewers) on how to adapt the methodology of a systematic…

BACKGROUND: A quality assessment tool for diagnostic accuracy studies, named QUADAS, has recently been developed. Although QUADAS has been used in several systematic reviews, it has not been formally validated. The objective was to evaluate the validity and usefulness of QUADAS. METHODS: Three reviewers independently…

INTRODUCTION: Access to musculoskeletal healthcare services in Sub-Saharan Africa is inadequate. As osteoarthritis is the most prevalent chronic osteoarticular disease globally, it's essential to understand its social and economic impact, as well as the determinants of inequities in access to healthcare services in Sub…

INTRODUCTION: The global burden of malnutrition is compounded by the challenges of obesity and sarcopenia, a combination known as sarcopenic obesity. This condition, defined by increased fat mass alongside declining muscle mass and function, poses significant health risks, including metabolic dysregulation and cardiova…

OBJECTIVE: This systematic review will aim to evaluate the effectiveness of telemedicine interventions compared with traditional or in-person care in improving medication adherence and clinical outcomes among adult patients with tuberculosis in low- and middle-income countries. INTRODUCTION: Tuberculosis remains a maj…

INTRODUCTION: Traumatic brain injury (TBI) is a leading cause of mortality and disability worldwide. In the USA, individuals who racially identify as African American or Black experience disproportionately higher rates of TBI and sustain worse prognosis compared with White patients; however, this population continues t…

BACKGROUND: Nasopharyngeal carcinoma (NPC) is the fourth-most-prevalent cancer in both Indonesia and Asia. Globally, an estimated 133,354 cases and 80,008 deaths were attributed to NPC in 2020. Early diagnosis plays a key role in managing NPC. Molecules found in bodily fluids, such as saliva, contain compounds (includi…

INTRODUCTION: International labor migrants form a significant part of the global workforce, particularly in the Gulf Cooperation Council (GCC) countries, which host around 11% of the world's migrant workforce. This high concentration presents unique challenges in healthcare access and delivery. This systematic review a…

OBJECTIVE: This review will investigate the effect of edible marine seaweed on plasma glucose in healthy, at-risk, and type-2 diabetic individuals. INTRODUCTION: Edible marine seaweed has potential as a dietary supplement for individuals with varying glycemic status, including healthy individuals, those at risk of dia…

OBJECTIVE: This scoping review aims to map the existing literature on physical activity-based interventions for the management of dementia and cognitive impairment in sub-Saharan Africa. INTRODUCTION: Dementia and cognitive impairment are growing public health concerns in sub-Saharan Africa, where the number of affect…

INTRODUCTION: Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are effective methods carried out widely in patients with end-stage hip and knee osteoarthritis (OA). Despite the trend towards shared decision-making in surgical decisions, patients often struggle to fully participate due to a lack of informa…

BACKGROUND: According to the 2018 bundle guidelines of the Surviving Sepsis Campaign, many emergency departments and intensive care units currently adopt the hour-1 bundle as a standard practice for sepsis management. However, recent studies on the hour-1 bundle for sepsis treatment have yielded inconsistent results, r…

BACKGROUND: Foodborne and waterborne illnesses affect over four million Canadians annually and pose a preventable burden on the nation's healthcare system. Climate change can increase the risk of such illnesses by increasing the likelihood of exposure to contaminants. As climate change progresses, it is imperative to b…

BACKGROUND: Self-reported health is a widely used health indicator in surveys and questionnaires. The measure gained attention when research identified its association with mortality in the 1970s and 1980s. The measure is also associated with morbidity and other health outcomes such as the utilisation of health service…

BACKGROUND: Equity, diversity and inclusion (EDI) in the healthcare field are crucial in meeting the healthcare needs of a progressively diverse society. In fact, a diverse healthcare workforce enables culturally sensitive care, promotes health equity and enhances the understanding of various needs and patients' viewpo…

OBJECTIVE: This review aims to synthesize the experiences of informal caregivers of people with dementia in low- and middle-income countries (LMICs). INTRODUCTION: Globally, the burden of dementia is increasing disproportionately in LMICs. Informal caregivers play a vital role and face multiple challenges in LMICs, ev…

INTRODUCTION: Physical activity and exercise are crucial to counteract physical and cognitive decline in old age. Home-based exergame training can be a solution to overcome physical inactivity. This systematic review aims to provide a comprehensive overview of home-based exergame interventions and evaluate their effect…

INTRODUCTION: Public policymakers are increasingly engaged in participatory model building processes, such as group model building. Understanding the impacts of policymaker participation in these processes on policymakers is important given that their decisions often have significant influence on the dynamics of comple…

INTRODUCTION: Reproductive coercion (RC) describes behaviours that interfere with an individual's reproductive autonomy and decision-making. RC can be a form of intimate partner violence and overlaps with other forms of gender-based violence, such as sexual violence. Health settings are well placed to identify and inte…