97,503 papers found

BACKGROUND: Insulin has traditionally been viewed as a 'last resort' in the treatment of type 2 diabetes. However, accumulating evidence on the benefits of early insulin initiation brings this traditional viewpoint into question. Increasing recognition of the importance of insulin therapy in type 2 diabetes has also ra…

OBJECTIVE: To Investigate the cervical cancer patients' knowledge and situation concerning cervical cancer screening and explore the connection of cervical cancer screening status and clinical stage at diagnosis of cervical lesions. METHODS: Questionnaires were done for the cervical cancer patients who went to Peking…

This paper is a continuation of the author's study published in 1975. The teeth of the school children included in the study were first examined in 1952, re-examined in 1972 and subsequently at 5-year intervals. Children in the village of Salo had drinking water with a high fluride content and those in the village of S…

Northern forests are important ecosystems for carbon (C) cycling and lakes within them process and bury large amounts of organic-C. Current burial estimates are poorly constrained and may discount other shifts in organic-C burial driven by global change. Here we analyse a suite of northern lakes to determine trends in…

Hypertension has emerged as important public health problem in India. During the later half of the last century, epidemiological studies in India reported that hypertension (diagnosed by systolic blood pressure (BP) ⩾160 and/or diastolic BP ⩾95 mm Hg) increased from about 1% in 1950's to 15%…

The Punung Fauna is a key component in the biostratigraphic sequence of Java. It represents the most significant faunal turnover on the island in the last 1.5 million years, when Stegodon and other archaic mammal species characteristic of earlier Faunal stages were replaced by a fully modern fauna that included rainfor…

In a retrospective study we tried to define the diagnostic value of different x-ray studies in 43 histologically proved acoustic neuromas. We divided the examinations into such which definitely confirmed a clinical suspicion i.e. formed the last preoperative studies, and into others, which only increased the clinical s…

In the past 9 years, 1,196 patients whose lower extremity was threatened because of infrainguinal arteriosclerosis have been treated at Montefiore Hospital. In the last 6 years, limb salvage was attempted in 679, or 90% of 755 patients. Femoropopliteal (318), small vessel (204) and axillopopliteal (29) bypasses were us…

During the past 10 years the authors have treated 17 patients on their department because of got stuck or injury-causing rectal foreign bodies. In 12 cases swallowed, in 3 cases "per anum"-placed up foreign bodies were observed, in 2 cases penetrating anorectal injury caused by the foreign body. In 9 cases after succes…

During the last 5 years a continuous increase of the number of intoxications with the analgesic paracetamol has been realized. Most cases were due to attempted suicides whereas few cases resulted from accidental overdosing to small children. In the latter case two to threefold overdoses often caused serious intoxicatio…

This study examined the efficiency of walking with a backpack load as a method for improving physical fitness. Forty-four subjects (average age, 18.8 years) marched at a speed of 5 km/hr for 30 minutes a day, five days a week. Thirty-two subjects walked for 3 weeks with a 3-kg backpack load; 6 subjects marched for 4 we…

OBJECTIVES: To identify factors associated with progressive anisometropia after bilateral intraocular lens (IOL) implantation in patients with pediatric cataract. METHODS: Clinical and standardized questionnaire data were collected for Sixty-eight patients with pediatric cataract (136 eyes) who underwent bilateral IOL…

While 2021 ended with the world engulfed in the COVID-19 Omicron wave, 2022 has ended in almost all countries, except China, with COVID-19 being likened to the flu. In this context, the U.S. Food and Drug Administration (FDA) has authorized only 37 new drugs this year compared to an average of 52 in the last four years…

BACKGROUND: Oxidative hair dyes are an important source of chemical exposure and a major risk factor for the development of occupational and non-occupational allergic contact dermatitis (ACD) worldwide. OBJECTIVE: To identify the frequency of common allergens associated with occupational and non-occupational ACD to ha…

This study aimed at assessing the association of breastfeeding with maternal body mass index (BMI), waist circumference, fat mass index, fat free mass index, android/gynoid fat ratio and bone mineral density. In 1982, the maternity hospitals in Pelotas, Rio Grande do Sul State, Brazil, were daily visited and all live b…

BACKGROUND: Gait and function may deteriorate with time in patients with spastic diplegia. Single-event multilevel surgery often is performed to either improve gait or prevent deterioration. However it is unclear whether the presumed gait improvements are durable. QUESTIONS/PURPOSES: We therefore determined whether (1…

OBJECTIVE: To assess the outcome of stereotactic radiosurgery (SRS) for patients with benign skull base tumors and trigeminal-related facial pain. METHODS: We undertook a retrospective review of 31 consecutive patients (25 women, 6 men) with benign skull base tumors and trigeminal pain who underwent SRS between 1991 a…

OBJECTIVES: A cross-sectional study over a period of 30 years was used to investigate the development of overweight and obesity in school children. Of particular interest is the question of whether the overweight epidemic is continuing to increase, as often postulated, or whether a stagnation point or the start of a re…

INTRODUCTION: The major advances in neonatal intensive care have made less useful the Waterston's criteria for esophageal atresia (EA) and/or tracheoesophageal fistula (TEF), and other prognostic classifications have been reported. The aim of this study was to determine the influence of various parameters on the outcom…

cN-II is a cytosolic 5'-nucleotidase with preference for IMP and GMP over AMP. The enzyme has been extensively studied over the last 20-30 years both for its enzymatic activity, structure, role in nucleotide metabolism and in cell biology, as well as in diseases. With the aim of highlighting the complexity of th…