42,479 papers found

BACKGROUND: Silicosis is a progressive fibrotic lung disease caused by chronic inhalation of crystalline silica. Increasing evidence indicates that oxidative stress plays a central role in linking silica exposure to inflammation, tissue injury, and fibrosis. We conducted a systematic review to critically appraise the c…

BACKGROUND: Central stimulants improve core ADHD symptoms, yet day-to-day benefit and tolerability vary under sustained psychosocial or financial stress. We reviewed clinical outcomes relevant to stress-linked vulnerability and integrated mechanistic evidence on stress-sensitive prefrontal-nucleus accumbens dopamine-gl…

Cavernous malformations (CMs) are vascular lesions that can lead to seizures or hemorrhage. Although pregnancy involves hormonal and circulatory changes that might influence CM behavior, whether it increases the risk of bleeding is unclear. We performed a systematic review using PubMed/MEDLINE and Scopus of publis…

Exposure to potentially traumatic events (PTEs) during childhood and adolescence is relatively common and may result in the development of post-traumatic stress disorder (PTSD). Recent studies have demonstrated the utility of the network approach for examining PTSD symptoms. However, to date, no systematic review has f…

BACKGROUND: Montelukast, a selective leukotriene receptor antagonist, is widely used in the treatment of bronchial asthma and allergic rhinitis (AR). Although it is a well-tolerated drug, there are reports of possible central nervous system side effects, including, for example, mood changes and suicidal thoughts. There…

Cerebral cavernous malformations (CCMs) are clusters of dilated, thin-walled vascular channels that pose significant neurological risks, particularly in pediatric patients. While stereotactic radiosurgery (SRS) has been explored as a non-invasive treatment modality, its safety and efficacy in children remain incomplete…

The supratrochlear artery (STA) is one of the terminal branches of the ophthalmic artery, coursing through the medial forehead and glabellar region to supply the central upper face. Although relatively small in caliber, it holds considerable clinical importance because of its anatomical variations and its communication…

OBJECTIVE: This review aims to assess the efficacy and safety of different supplements, such as L-theanine, caffeine,L., andfor improving ADHD symptoms, to determine the most effective supplement and provide insight for medical practice. METHODS: International databases (PubMed/MEDLINE and Scopus) were searched for En…

A common hallmark of several neuropsychiatric conditions is an altered protein homeostasis. In this context, ubiquitination has emerged as one of the most important post-translational modifications, regulating various intracellular processes such as protein degradation, autophagy, protein activation, and protein-protei…

This review aimed to comprehensively summarize the role of long non-coding RNA (lncRNA) in gliomas, the most common malignant tumors in the central nervous system, and explore their potential clinical applications. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a s…

In the present study, we conducted a scoping review to provide an overview of the existing literature on the carbocyanine dye DiI, in human neuroanatomical tract tracing. The PubMed, Scopus, and Web of Science databases were systematically searched. We identified 61 studies published during the last three decades. Whil…

BACKGROUND: Clinical reasoning (CR) is a holistic and recursive cognitive process. It allows nursing students to accurately perceive patients' situations and choose the best course of action among the available alternatives. This study aimed to identify the randomised controlled trials studies in the literature that co…

BACKGROUND AND PURPOSE: Trans-spinal direct current stimulation (tsDCS) is a noninvasive stimulation technique that applies direct current stimulation over spinal levels. However, the effectiveness and feasibility of this stimulation are still unclear. This systematic review summarizes the effectiveness of tsDCS in cli…

BACKGROUND: Repeated implantation failure (RIF) is considered one of the major challenges facing clinician in assisted reproduction technologies (ART) despite the significant advances that have been made in this field. Platelet rich plasma (PRP), also known as autologous conditioned plasma, is a protein concentrate wit…

INTRODUCTION: Changes in executive functions associated with alcohol consumption are frequently found in alcohol use disorder. Neuropsychological rehabilitation can play an essential role as an effective treatment in the recovery from these deficits, leading to the maintenance of abstinence. However, there are still so…

To review preclinical and clinical data relevant to daptomycin lock therapy in catheter-related bloodstream infection (CRBSI).Systematic review in PubMed, Scopus and clinical trial registries.Preclinical data demonstrate daptomycin lock solution stability and compatibility with heparin, good biofilm penetration, bacter…

Given the relatively high frequency of central nervous system infections and considerable mor- tality and morbidity reported to be caused by herpes simplex viruses among the other viral agents, having a clear knowledge about their epidemiological profile seems necessary. This systematic review and meta-analysis aimed t…

OBJECTIVE: The aim of this study was to analyze the effect of the pharmacological treatment on the sleep patterns of children with attention deficit hyperactivity disorder (ADHD). DATA SOURCE: A high-sensitivity electronic search was performed in the following databases: Cochrane Library, MEDLINE via PubMed, LILACS vi…

OBJECTIVE: Although neuroimaging investigations have revealed significant changes in brain structure in fibromyalgia (FM) patients, these findings are inconsistent. The current study conducted a systematic review and meta-analysis of voxel-based morphometric studies in order to comprehend those alterations in brain str…

Photoelectrochemical (PEC) sensing is an emerging technological innovation for monitoring small substances/molecules in biological or non-biological systems. In particular, there has been a surge of interest in developing PEC devices for determining molecules of clinical significance. This is especially the case for mo…