97,495 papers found

The incidence rates of bronchogenic carcinoma based upon 414 cases that occurred in Olmsted County, Minnesota, over a period of 45 years are described. Histologic preparations were available for 97% of cases and were reviewed by one pathologist. The overall average annual age-adjusted rates per 100,000 person-years for…

BACKGROUND: Social isolation and loneliness are critical to the health of older adults, but they have not been well-described at the end of life. OBJECTIVES: To determine the prevalence and correlates of social isolation and loneliness among older adults in the last years of life. DESIGN: Nationally representative, c…

IMPORTANCE: In light of the promising neuroprotective properties of recombinant human erythropoietin (RHEpo), the Swiss EPO Neuroprotection Trial was started to investigate its effect on neurodevelopment in very preterm infants. The results of the primary and secondary outcome analysis did not show any effect of RHEpo…

BACKGROUND: Giant pituitary adenoma (≥4 cm) is a rare tumor whose clinical features and prognosis are not well known. AIM: To evaluate the clinical characteristics and therapeutic outcomes of giant non-functioning PA (gNFPA). PATIENTS AND METHODS: A retrospective multicenter study of gNFPA patients diagnosed i…

Acute promyelocytic leukemia (APML) is characterized by promyelocytic leukemia retinoic acid receptor alpha (PML-RARA) fusion gene resulting from at (15;17) translocation. The purpose of this study was to evaluate the clinical outcomes of patients with APML treated with a combination of all-trans retinoic acid (ATRA) a…

OBJECTIVE: The aim of this study was to investigate the effects of the February 6 earthquake on the bacteria grown in urine cultures and antibiotic resistance of patients admitted to the urology outpatient clinic. METHODS: In this study, 11,397 urine samples requested by the urology outpatient clinic between January 2…

Against the backdrop of rising STI incidence among the heterosexual population, sexually active single people are at particularly high STI transmission risk. Gaining insight into circumstances related to condoms non-use in this population is therefore important for developing effective health interventions.The national…

BACKGROUND: Hypothyroidism has been shown to contribute to enhanced atrial arrhythmogenesis, resulting in atrial fibrillation (AF) development in animal models and clinical populations. We aimed to elucidate whether high thyroid-stimulating hormone (TSH) levels are related to outcomes of catheter ablation of AF. METHO…

BACKGROUND: The superiority of autogenous conduits in infrainguinal bypass surgery is well established. At our institution, arm vein is utilized as the last autogenous option for infrainguinal bypass surgery. The aim of this study was to review the long-term outcomes of last autogenous option arm vein bypass. METHODS:…

The efficacy of extended-release felodipine in preventing ergonovine-induced myocardial ischaemia was assessed in 14 patients (12 male, two female, aged 56 +/- 7 years) with Prinzmetal's variant angina. Four of the patients had normal coronary arteries, eight had one-vessel and two had two-vessel disease. The ergonovin…

BACKGROUND: Current use of menopausal hormone therapy (HT) increases the risk of venous thromboembolism (VTE) and the formulations used may affect risk. METHODS: A total of 1,058,259 postmenopausal UK women were followed by record linkage to routinely collected National Health Service hospital admission and death reco…

OBJECTIVE: A retrospective study (2007-2012) of acute alcohol intoxication (AAI) in the paediatric Emergency Department (ED) (Hospital Sant Joan de Déu, Barcelona) demonstrated a decrease in the rates of AAI over the last two years. Aim: to determine if this decile continued during the following 5 years and to des…

OBJECTIVE: To summarize the mid-term effectiveness of Coflex non-fusion internal fixation treatment of degenerative lumbar disease. METHODS: From October 2008 to December 2010, a retrospective analysis was carried out on 39 patients (29 males and 10 females) diagnosed as degenerative lumbar disease and treated with Co…

Julia Kydd, Martin Nielsen and Andrew Waller highlight some of the key presentations given at last year's 11th International Equine Infectious Diseases Conference, which was held virtually.

In this critical review the applications of gold catalysed reactions in total synthesis during the years since our last article are reviewed. At the end of this article a literature analysis is conducted to evaluate the progress in this field.

With the 2006 hurricane season near and memories of last year's storms painfully fresh, here are 12 priorities hospitals should set in preparing for natural and other disasters.

There was a huge surprise awaiting Royal College of Midwives General Secretary Ruth Ashton at her retirement party last week. BBC social services correspondent Niall Dickson was on hand with the big red book' to say 'Ruth Ashton, this is your professional life'. Friends, family and colleagues organised the event in whi…

The extent to which the vagaries of the history of biology have influenced subsequent developments is often surprising. In particular, the early dichotomies between individual fields of enquiry have sometimes led to the disregard of important biological phenomena. The development of biological oceanography over the las…

OBJECTIVES: Resective or ablative frontal lobe surgery is an established treatment for drug-resistant frontal lobe epilepsy (FLE) in pediatric and adolescent patients, typically performed with curative intent. Emerging evidence suggests potential benefit even when used with palliative intent, though long-term outcome d…