97,290 papers found

Several strategies and alternative therapies have been used to provide analgesia for labour pain. Over the last few years, a number of improvements have enhanced the efficacy and safety of neuraxial analgesia and ultimately have improved mothers' satisfaction with their birth experience. As labour analgesia is a field…

Anaplastic thyroid cancer (ATC) is one of the most deadly cancers in humans. Searching a PubMed database, studies published during the last 20 years, 63 publications dealing with treatment of patients were identified. Cohort studies comprised 6,609 patients with the median age 68 years (range 57-77 years). The median s…

BACKGROUND: Dementia is a terminal illness marked by progressive cognitive decline. This study characterized trajectories of functional status and health care use for people with and without dementia at the end of their life. METHODS: We used the Health and Retirement Study linked with Medicare claims to generate a se…

OBJECTIVE: Cerebrospinal fluid (CSF) markers of neurodegeneration [neurofilament light chain (NFL), total Tau (T-Tau)], tau pathology [phosphorylated tau (p-Tau)], glial cell damage or activation [glial fibrillary acidic protein (GFAP)], and brain amyloidosis [β-amyloid 1-42 (Aβ42)] are useful for diagnosis…

Purpose The benefits of annual surveillance mammography in older breast cancer survivors with limited life expectancy are not known, and there are important risks; however, little is known about mammography use among these women. Materials and Methods We used National Health Interview Study data from 2000, 2005, 2008,…

OBJECTIVE: To investigate the oral health knowledge, attitudes and behavior of urban, rural and suburban adults in Deyang, PR China, and analyze the influence of several variables on the utilization of dental services. METHODS: 1010 adults with 35-44 years old from urban, rural and suburban areas were interviewed by Q…

INTRODUCTION: Osteonecrosis of the femoral head (ONFH) is a progressive and disabling disease with severe socioeconomic burdens. In the last 30 years, a growing number of publications have reported significant advances in understanding ONFH. However, only a few studies have clarified its global trends and current statu…

BACKGROUND: Comorbidities are common in multiple sclerosis (MS); little is known in neuromyelitis optica spectrum disorders (NMOSD) or outside high-income regions. OBJECTIVE: Compare comorbidities in MS/NMOSD patients, Zambia. METHODS: Comorbidities were compared for MS/NMOSD patients from Zambia's University Teachin…

A long-term follow-up report is given on three children with stress-induced bursts of ventricular activity, occasionally proceeding to ventricular fibrillation causing syncope. All patients were treated with a beta-blocking agent as prophylaxis for 12, 10 and 6 years, respectively. Case 1 has no signs of organic heart…

For a period of 17 years a total of 377 patients have been on hemodialysis treatment--242 men (64.2 per cent) and 135 women (35.8 per cent). During the first nine years the difference between men and women was significant (71.6 and 28.4 per cent respectively), in the next 8 years however it fell--accordingly 58.6 and 4…

OBJECTIVES: To analyze the evolution of prostate cancer (PCa) in our community health area over the last years, in terms of incidence, clinical-epidemiological characteristics, and cancer-specific mortality. METHODS: Retrospective analysis of the medical records of patients with PCa in our hospital over the 1991-2003…

It is commonly thought that the longer the time since last earthquake, the larger the next earthquake's slip will be. But this logical predictor of earthquake size, unsuccessful for large earthquakes on a strike-slip fault, fails also with the giant 1960 Chile earthquake of magnitude 9.5 (ref. 3). Although the time sin…

BACKGROUND: The continuation of preventive drugs among older patients with advanced cancer has come under scrutiny because these drugs are unlikely to achieve their clinical benefit during the patients' remaining lifespan. METHODS: A nationwide cohort study of older adults (those aged ≥65 years) with solid…

PURPOSE: Studies investigating hyperostosis frontalis interna (HFI) in acromegaly are limited. We aimed to investigate HFI and the association of disease control with frontal bone thickness (FBT) in acromegaly. METHODS: Adult patients with acromegaly were grouped according to the presence of HFI on the baseline MRI: G…

OBJECTIVES: The aim of this study was to evaluate the epidemiological situation of syphilis in the Slovak Republic in the period of the past two decades. BACKGROUND: In last decade, the incidence of syphilis has decreased in European countries by 13%. However, several countries reported an increase in the trend of syp…

BACKGROUND: The safety of mental health care provided remotely via the internet, in particular, the probability of suicide after contact, is not known. METHOD: An observational cohort study of patients registered with the MindSpot Clinic an Australian national digital mental health service (DMHS), linked to the Nation…