5,042,454 papers found

Documenting systematic searches promotes transparency, reproducibility, and integrity in research. In recent years, various reporting guidelines have gained widespread recognition and adoption, and some journals and funders require researchers to provide a detailed account of their search strategies. Documentation of s…

Depression is a well-known co-morbidity of cancer. A possible intervention for depression is psychological treatment defined as psychotherapy provided by a psychologist. In this narrative review we investigated the effect of psychological treatment on depression for patients with cancer. Six Cochrane reviews of 38 stud…

This clinical review on the treatment of patients with gastroparesis is a consensus document developed by the American Motility Society Task Force on Gastroparesis. It is a multidisciplinary effort with input from gastroenterologists and other specialists who are involved in the care of patients with gastroparesis. To…

Three aspects of the role of clinical evidence in guiding therapy in the field of neonatology are presented: 1) what is embodied in the concept "evidence-based medicine"? 2) the contribution of the Cochrane Collaboration and its Neonatal Review Group in summarizing and disseminating evidence, in the form of systematic…

Systematic literature reviews and meta-analyses are important research designs used to summarize and derive conclusions about the collective evidence on a focused research question in a structured, reproducible manner. The goal of this Methodology Minute is to describe how to conduct a systematic literature review and…

The systematic literature review is a powerful tool for summarizing and evaluating current knowledge related to a specific research question. Systematic reviews have many advantages over traditional narrative reviews. A meta-analysis of data from a systematic review can provide a better estimate of a treatment effect t…

AL amyloidosis presenting as a solitary mediastinal mass is a rare occurrence, with only a few cases reported in the literature. We describe a case of a man presenting with a mediastinal mass diagnosed as amyloidosis, confirmed by mass spectrometry to consist of lambda light chains. Here we review the literature and di…

The use of image quality parameters in digital mammography such as contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR) and detective quantum efficiency (DQE) has been widespread, with the intention of detector evaluation and/or quantitative evaluation of the system performance. These parameters are useful in ens…

Here, we review several articles of original research published in 2008 that concerned the toxicity of metal and carbon-based nanoparticles. Articles were selected from the MEDLINE PubMed database, all published or pre-published during 2008 and relating to nanomaterials, -particles or -structures and toxicity or health…

This review summarizes the clinical importance of 18 systematic reviews and guidelines on psoriasis published or indexed between November 2008 and October 2009. The topics covered include guidance on the use of topical, systemic and biological therapies for the treatment of psoriasis; comorbidities associated with psor…

All physicians are familiar with the type of general review articles found in many medical journals. Systematic reviews are different. They apply a strict, scientific methodology to the reviewing process to produce a review that is comprehensive, reliable, and as free from bias as possible. As a result, systematic revi…

OBJECTIVE: The aim of the study was to present the methods for a fit-for-purpose systematic review designed to assess the health effects of jet fuel exposure in military settings by synthesizing data from epidemiologic, animal toxicological, and mechanistic studies. METHODS: Methods followed the US Environmental Prote…

The aim of the present study was to train a natural language processing model to recognize key text elements from research abstracts related to hand surgery, enhancing the efficiency of systematic review screening. A sample of 1600 abstracts from a systematic review of distal radial fracture treatment outcomes was anno…

BACKGROUND: Phytosterols (PS), as a kind of plant active ingredients, have many benefits to human health. However, there is currently no comprehensive overview of the clinical evidence and an assessment of the evidence quality. PURPOSE: We conducted an umbrella review, which incorporated verification spanning a number…

INTRODUCTION: Medication errors are common events that compromise patient safety and are prevalent in all health-care settings. This umbrella review aims to systematically evaluate the evidence on contributory factors to medication errors in health-care settings in terms of the nature of these factors, methodologies an…

PURPOSE: International guidance on health-care transition has existed for over a decade; however, many unanswered questions remain. This systematic review of reviews aimed to answer the question: is a later age of transfer from pediatric to adult health care associated with improved health and health service outcomes?…

Objective - Update the last known umbrella review and summarize the available high-quality evidence from systematic reviews on the effectiveness of non-pharmacological and non-surgical interventions for patients with knee OA. Methods - The systematic reviews were identified thought electronic databases such as, MEDLINE…

Several outcome measures have been systematically implemented to be used in palliative care. However, routine use in clinical practice is not without ethical challenges, which are not commonly addressed. The objectives of this study are therefore (I) to identify the ethical challenges/issues of outcome measurement in p…

OBJECTIVES: Pooled-studies publications (PSPs) present statistical analyses of multiple randomized controlled trials without a systematic literature search or critical appraisal. We explored the characteristics of PSPs and their potential impact on a systematic review (SR). STUDY DESIGN AND SETTING: We systematically…