98,343 papers found

Sea level change during the Quaternary is primarily a consequence of the cyclic growth and decay of ice sheets, resulting in a complex spatial and temporal pattern. Observations of this variability provide constraints on the timing, rates, and magnitudes of the changes in ice mass during a glacial cycle, as well as mor…

The biochemical and physiologic bases for clinical use of ionized calcium, magnesium, or lactate measurements are described, with emphasis on the critical care setting. Ionized calcium or magnesium are usually measured to prevent hypocalcemia or hypomagnesemia, conditions that most affect cardiovascular function. Blood…

Because of its subaerial exposure the Asal rift segment provides an exceptional opportunity to quantify the deformation field of an active rift and assess the contribution of tectonics and volcanism to rifting processes. The present topography of the Asal rift results from the tectonic dismemberment during the last 100…

A variant of the onlay island flap urethroplasty in severe hypospadias repair is described. The principles of the technique include mobilization of the urethral plate without dividing it, release of chordee, creation of a pedicle island flap on the dorsal penile skin with redundant vascularized tissue that is transpose…

The reproductive rates of about 50 species of Australian rodents were studied by calculating allometric equations for the relationships between female body weight, litter size, length of gestation and weaning periods as well as age of sexual maturity.Members of the subfamily Hydromyinae, which invaded Australia 5-10 mi…

The authors present the results of an inquiry conducted in the principal hospitals of Algeria. The number of cases of visceral leishmaniasis recorded over the last ten years (1965 to 1974) totaled 497. The disease occurs essentially in children under 5 years of age (94%); it is mainly detected in central and eastern pa…

In 1898 the first radical operation for carcinoma of the pancreas was performed by Codivilla in Bologna. Kausch followed in 1913 and Whipple perfected the technique of duodenopancreatectomy. The central position of the pancreas causes technical difficulties. Carcinoma of the head of the pancreas frequently causes icter…

OBJECTIVE: To characterize shifts from the 1960s to the first decade in the 21st century as to diagnostics, case-mix, and surgical management of pediatric patients undergoing permanent CSF diversion procedures. METHODS: One hundred and thirty-four patients below 15 years of age were the first time treated with CS…

INTRODUCTION: There has been (and still is) some controversy about the treatment of malleolar fractures with an additional fracture of the posterior malleolus (Volkmann triangle) in the last few years. Should a posterior malleolus with a fragment that is larger than 25% of the articular surface be fixed? Can long-term…

Visual snow is a persistent visual disturbance in which small dots of light appear across the visual field of both eyes, like snowfall. The condition is not widely known, but an increasing number of cases have been described in the last 5 - 6 years. Many patients have consulted a number of specialists without…

•More than 70% of all deaths in the BRICS countries are attributable to noncommunicable diseases.•There have been marked changes in physical activity levels, time use, and energy expenditure in these nations over the last 20 years.•There are marked gender differences in physical activity in 4 of th…

In the last two decades, an enormous expansion of evidence has been produced in upper airway research. When writing the first EPOS document in 2005 only 5 RCT per year were performed in the area of CRS, in 2007 this changed to 25 per year and it became even higher in the recent years. Randomized Controlled Trials (RCTs…

Applications of conducting polymers to biosensors have recently aroused much interest. This is because these molecular electronic materials offer control of different parameters such as polymer layer thickness, electrical properties and bio-reagent loading, etc. Moreover, conducting polymer based biosensors are likely…

Heart failure is a common clinical problem, affecting at least 5 million Americans. There have been substantial advances in the understanding and treatment of heart failure in the last several years. We review current concepts for the evaluation and treatment of the various manifestations of patients with heart failure…

The authors presented 6 cases of malignant neoplasms of intestine. Five of them were undergone emergency surgery, while one elective, due to complaints notified previously for a longer time. In all cases a segmental resection of intestine was done. Two patients were complementarily treated using chemiotherapeutics. Thr…

In the last 5 years we have performed 14 phase I studies in our department. Eight of these trials involved evaluation of both the clinical and the pharmacokinetic behaviour of novel anti-cancer agents. The remainder investigated various aspects of drug delivery, targetting or resistance modification with existing anti-…

A case of massive chronic fetomaternal transfusion with a loss of 500 ml blood is reported. A review of 24 cases covering the last 10 years shows that chronic fetomaternal transfusions do not lead to intrauterine dystrophy. During birth there is a danger of acute decompensation, which led to an irreversible shock and d…

The benign systemic disorders with involvement of the spleen are divided into haematologic diseases, thesaurismosis, collagenosis, morbus Boeck, infectious diseases, parasitosis and others. 4/5 of the cases are haematologic diseases of the erythrocytic, the thrombocytic and lymphatic system as well as myeloproliferativ…

In the Department of Pediatric surgery, during the last ten years, 190 patients with supracondylar fractures (second and third degree, according to Bauman's classification) have been treated. The operation was performed in only 5% of all hospitalized cases. There were only one patient with neurological and vascular com…