2,693 papers found

Many countries (USA, Australia, Canada, Latin America, Spain, France, SRN) have national or international systems (e.g. Networked Digital Library of Theses and Dissertations--NDLTD), which openly (NDLTD) or commercially (University Microfilm International--UMI) present up to 50% of master dissertations and doctoral the…

Palmoplantar pustulosis (PPP) is a rare, recurrent skin disorder that presents a major challenge to clinical therapy. We report a case of a 69-year-old woman with a 20-year history of psoriasis with skin manifestations and clinical and pathologic features consistent with PPP. After intolerance to apremilast and unsucce…

Systematic review has generally been accepted as an effective, more complete, repeatable, and less biased type literature review that can successfully lead to evidence-based conclusions. This study attempts to develop a framework for systematic review with guidelines on how to conduct an effective systematic review for…

This review describes the sequential learning from initial free tissue grafting reconstructive techniques to the current use of vascularized flaps. Outcomes and limitations of current endoscopic reconstructive techniques are discussed, including a systematic review of the outcomes of endoscopic endonasal techniques to…

UNLABELLED: The objective of this study was to evaluate the structure and contents of the websites of the major journals in general pediatrics. A comprehensive search of the Internet was carried out to identify all pediatric journals in English that are listed in the Scientific Citation Index. Websites of 11 journals i…

BACKGROUND: Maximizing resection while preserving function is vital in adult glioma surgery, especially in the eloquent cortex. We examined how intraoperative functional mapping-performed during awake craniotomy or under anesthesia-relates to long-term neurological, functional, and neurocognitive outcomes beyond the im…

BACKGROUND: Low back pain clinical practice guidelines consistently recommend against the routine ordering of spinal imaging; however, imaging is frequently requested in primary care, without evidence of benefit. Imaging reports frequently identify degenerative features which are likely to be interpreted as 'abnormal',…

OBJECTIVE: The aim of the presented study was to analyse the types and quantity of inquiries received at Drug Information Centre in Bratislava during the period from May 1997 to May 2006. The study analyses also the profile of the users of the latter centre with focus on the perception of drug risk, adverse drug reacti…

INTRODUCTION: Posterior urethral valves (PUV) remain the most common cause of severe congenital lower urinary tract obstruction in boys and a leading pediatric cause of chronic kidney disease (CKD) and end-stage kidney disease (ESKD). Despite decades of research, management decisions across antenatal counseling, postna…

To promote optimal healthcare delivery in type 2 diabetes mellitus (T2DM) following the outbreak of coronavirus disease 2019, adopting home-based physical activity (PA) is being seriously considered. Therefore, this study aims to outline the characteristics of exercise protocols for home-based PA and the challenges and…

Evidence to support exercise training guidelines for patients who have undergone bariatric surgery is exceedingly limited. The purpose of this preliminary study was to evaluate the feasibility of a 12-week supervised, resistance training (RT) program and its short-term effects on physical fitness and functional strengt…

BACKGROUND: Laparoscopic cholecystectomy is now accepted as a surgical procedure for acute cholecystitis when it is performed by an expert surgeon. There are several lines of strong evidence, such as randomized controlled trials (RCTs) and meta-analyses, supporting the introduction of laparoscopic cholecystectomy for p…

Rare diseases often lead to delayed diagnosis because clinical knowledge is fragmented across unstructured research, individual case reports, and heterogeneous data formats. This study presents ZebraMap, a multimodal knowledge map created to consolidate rare disease information and transform narrative case evidence int…

BACKGROUND: The exploitation of information extraction (IE), a technology aiming to provide instances of structured representations from free-form text, has been rapidly growing within the molecular biology (MB) research community to keep track of the latest results reported in literature. IE systems have traditionally…

AIMS: To explore the literature on strengths-based and culturally responsive care for pregnant individuals who use substances, and to identify the practice components and system enablers that reduce stigma, improve engagement, and support equitable outcomes. DESIGN: Narrative review with systematic features: protocoll…

Parameter-free assessment of the time-to-peak (TTP) histogram, termed 'TTP-distribution curve' (TDC), of dynamic susceptibility contrast-enhanced magnetic resonance imaging (DSC-MRI) was introduced as a robust method to evaluate cerebral perfusion. TDC-assessment works fully automatically without the need of an arteria…

OBJECTIVE: A pronounced burden is evident in individuals with asthma, with approximately half of them not adhering to their prescribed medication. Therefore, this study aimed to assess the pooled prevalence of anti-asthma medications non-adherence in Ethiopia. DATA SOURCES: A comprehensive search was conducted across…

Critical limb ischemia (CLI), a serious outcome of peripheral artery disease, is frequently associated with morbid outcomes. The available treatment modalities do not provide satisfactory results, leading to marked morbidities such as joint contracture and amputations, resulting in a high economic burden. The periphera…

INTRODUCTION AND OBJECTIVES: Bipolar disorder (BD) has been related to various cognitive dysfunctions as well as to a high prevalence of metabolic syndrome (MS), which seems to influence the cognitive performance of patients with BD. Therefore, different hypotheses have been generated to try to explain the pathophysiol…

Heart failure (HF) is a notable public health issue, and intravenous loop diuretics are frequently employed to address acute decompensated heart failure (ADHF) and alleviate symptoms of congestion. However, prolonged use of loop diuretics can lead to drug resistance, and some patients experience refractory volume overl…